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131.

산소유리라디칼이 뇌조직 미크로좀분획의 Na+-K+-ATPase 활성도에 미치는 영향

오세문(Sae Moon Oh)손영숙(Young Sook Son), 최길수(Kil Soo Choi), 임정규(Jung Kyoo Lim), 정명희(Myung Hee Chung) 대한약리학회 대한약리학잡지 14 Pages

대한약리학회 대한약리학잡지 1982, 제 18권 제 2호 1 1-14 (14 pages)

오세문(Sae Moon Oh)손영숙(Young Sook Son), 최길수(Kil Soo Choi), 임정규(Jung Kyoo Lim), 정명희(Myung Hee Chung) 저
...
- 4,300원
중추신경계의 혈관폐쇄 또는 충격손상에 의한 허혈병소에서 진행되는 병리적 변화에 산소유리라디칼이 중요한 역할을 할 것으로 시사되고 있다. 저자는 산소유리라디칼이 뇌조직에 미치는 영향 중 특히 신경세포 정지막전위 유지에 중요한 Na+-K+-ATPase의 활성도에 미치는 영향을 관찰하기 위하여 산틴산화효소 반응계와 뇌조직미크로좀을 이용하여 본 연구를 시행하였다. 미크로좀분획(microsomal fraction)을 산틴과 산틴산화효소와 함께 반응시켰을 때, 분획의 Na+-K+-ATPase의 활성도는 현저한 불활성화를 보인 반면, Mg++-ATPase의...
132.

Isolation and Characterization of Endosome Subpopulation in Chinese Hamster Ovarian Cells

Suh, Duk-Joon, Park, Mi-Yeon, Jung, Dong-Keun, Bae, Hae-Rahn 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 2 197-208 (12 pages)

Suh, Duk-Joon, Park, Mi-Yeon, Jung, Dong-Keun, Bae, Hae-Rahn 저
...
- 4,100원
Endosomes lower their internal pH by an ATP-driven proton pump, which is critical to dissociation of many receptor-ligand complexes, the first step in the intracellular sorting of internalized receptors and ligands. Endosomes are known to exhibit n great range of pH values that can vary between 5.0 and 7.0 within a single cell although the factors that regulate endosomal pH remain uncertain. To evaluate the morphological and topological differences of endosomes in the different stages, confocal...
133.

Effects of Insulin and IGFs on Phosphate Uptake in Primary Cultured Rabbit Renal Proximal Tubule Cells

Han, Ho-Jae, Park, Kwon-Moo 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 7 63-76 (14 pages)

Han, Ho-Jae, Park, Kwon-Moo 저
...
- 4,300원
The aim of present study was to characterize phosphate uptake and to investigate the mechanism for the insulin and insulin-like growth factor(IGF) stimulation of phosphate uptake in primary cultured rabbit renal proximal tubule cells. Results were as follows : 1. The primary cultured proximal tubule cells had accumulated 6.68±0.70 nmole phosphate/mg protein in the presence of 140 mM NaCl and 2.07±0.17 nmole phosphate/mg protein in the presence of 140 mM KCl during a 60 minute uptake period....
134.

Electrophysiological Responses of δ -Opioid Receptor Expressed on HEK293 Cells

Kim, Jin-Hyuk, Koh, Young-Ik, Chin, He-Min, Lee, Yong-Sung, Cho, Yeul-Hee, Kim, Kee-Soon 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 12 301-308 (8 pages)

Kim, Jin-Hyuk, Koh, Young-Ik, Chin, He-Min, Lee, Yong-Sung, Cho, Yeul-Hee, Kim, Kee-Soon 저
...
- 3,000원
of the transformed HEK293 cells with 1 mM 8-bromo-cyclic AMP, DPDPE failed to increase the voltage sensitive outward currents. On the other hand, naloxone completely abolished DPDPE-activated voltage sensitive outward current in the transformed HEK293 cells. The results of present study suggest that in the transformed HEK293 cells an activation of the δ-Opioid receptors by an opioid agonist DPDPE increases the voltage-sensitive potassium current as a result of decrement in cyclic AMP level.
135.

Phorbol Ester-Induced Periodic Contraction in Isolated Rabbit Jugular Vein

Ryu, Jae-Cheol, Jung, Dong-Keun, Lee, Sang-Ho 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 4 225-232 (8 pages)

Ryu, Jae-Cheol, Jung, Dong-Keun, Lee, Sang-Ho 저
...
- 3,000원
The present study was conducted to evaluate the effect of phorbol 12,13-dibutyrate (PDBu) on the contraction of rabbit jugular vein in vitro. PDBu concentrations of greater than 10 nM induced a periodic contraction which was composed of rapid contraction, plateau and slow relaxation. The frequency of periodic contraction increased as PDBu concentration increased. The PDBu-induced contraction was inhibited by staurosporine (100 nM), it was not changed by tetrodotoxin (1 μM). In Ca2+-free...
136.

Effects of Insulin and IGFS on Growth and Functional Differentiation in Primary Cultured Rabbit Kidney Proximal Tubule Cells -Growth and membrane transport-

Han, Ho-Jae, Park, Kwon-Moo, 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 1 191-202 (12 pages)

Han, Ho-Jae, Park, Kwon-Moo, 저
...
- 4,100원
The purpose of this study was to compare effects of insulin and IGFs on growth, apical membrane enzyme activities and membrane transport systems of primary cultured rabbit kidney proximal tubule cells. Results were as follows: 1. Insulin and IGF-I produced significant growth stimulatory effects at 5 X 10-10M. IGF-II(5 X 10 -10 M) did not stimulate significant cell growth. 2. Insulin stimulated the phosphorylation of a 97 KD protein. It was difficult to determine whether this band represents...
137.

Effect of Cyclic Nucleotides on Phorbol Ester-Induced Contraction in Rabbit Carotid Artery

Jung, Dong-Keun, Woo, Jae-Suk, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 4 39-50 (12 pages)

Jung, Dong-Keun, Woo, Jae-Suk, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 저
...
- 4,100원
This study was designed to clarify the action of cyclic nucleotides, cyclic AMP and cyclic GMP, on phorbol 12,13-dibutyrate (PDBu)-induced contraction in rings isolated from rabbit carotid artery. Arterial rings, 2 mm in width, were myographied isometrically in an isolated organ bath. PDBu produced slowly developing, sustained contraction in rabbit carotid artery, in a dose dependent manner, which was independent of extracellular Ca2+ PDBu-induced contraction was relaxed by staurosporine, which...
138.

Rapid Measurement of NH3 and Weak Acid Permeation Through Liposomes and Renal Proximal Tubule Membranes

Bae, Hae-Rahn, Suh, Duck-Joon, Lee, Sang-Ho 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 11 203-214 (12 pages)

Bae, Hae-Rahn, Suh, Duck-Joon, Lee, Sang-Ho 저
...
- 4,100원
of nonionized formic acid and initial rate of flux of formic acid in liposome, and the slope coincided with the value of permeability coefficient of formic acid measured in pH 7.0. These results show that techniques of stopped-flow and epifluorescence microscopy with entrapped fluorophore provide the precise method of measurement of very rapid transport of nonelectrolytes through membranes with the advantages of instantaneous mixing effect, good resolution time and easy manipulation.
139.

Contribution of Bulk Flow to Transport Mechanisms of the Membranes Surrounding Amniotic Fluid in the Rabbit

Lim, Young-Cheol, Lee, Sang-Jin, Sung, Ho-Kyung 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 8 79-90 (12 pages)

Lim, Young-Cheol, Lee, Sang-Jin, Sung, Ho-Kyung 저
...
- 4,100원
the present study is to assess the contribution of bulk flow to the regulatory mechanism of amniotic fluid volume and its ionic concentration in the membranes surrounding the amniotic fluid. For quantitative assessment, we prepared 4 kinds of artificial amniotic fIuids (isotonic isovolumetric, hypotonic isovolumetric, isotonic hypervolumetric and hypotonic hypervolumetric ones) by replacing 70% of amniotic fluid of pregnant rabbits with water or normal Tyrode solutions. Isoosmotic saline of 0.5...
140.

Ventilatory Responses to Continuous Negative Pressure Breathing(CNPB) in Awake Dogs

Cha, Eun-Jong, Goo, Yong-Sook 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 1호 4 37-50 (14 pages)

Cha, Eun-Jong, Goo, Yong-Sook 저
...
- 4,300원
Ventilatory responses to inhaled CO2 were measured during continuous negative pressure breathing (CNPB) in awake dogs. End expiratory lung volume (EELV) decreased linearly with pressure level during CNPB (correlation coefficient= 0.81, p<0.005) during air breathing. When CNPB was applied during 5% CO2 inhalation, the decrease in EELV was not significantly different (p<0.5) from that during air breathing. As a result of a lowered EELV, tidal volume (VT) significantly decreased by 22% and...

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