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151.

Indole, Indole-3-calbinol 및 Benzofuran이 간장 microsome과 cytosol의 약물대사 효소 활성도에 미치는 영향

차영남(Young-Nam Cha), 정진호(Jin-Ho Chung), David C. Thompson, Henry S. Heine 대한약리학회 대한약리학잡지 11 Pages

대한약리학회 대한약리학잡지 1985, 제 21권 제 1호 1 1-11 (11 pages)

차영남(Young-Nam Cha), 정진호(Jin-Ho Chung), David C. Thompson, Henry S. Heine 저
...
- 4,000원
이물질(xenobiotics) 대사에 관여하는 간장 microsome과 cytosol 효소 활성에 indole, indole-3-carbinol 및 benzofuran이 미치는 영향을 검색하기위하여 마우스에 이들 약물을 각각 5 mmole/kg씩 10일간 투여하여 다음 몇 가지의 성적을 얻었다. Benzofuran은 microsome 효소인 aniline hydroxylase, 7-ethoxycoumarin O-deethylase, p-nitrophenol UDPGA-transferase, epoxide hydrolase와 cytosol 효소인 glutathione S-tranferase, NADH : quinone reductase, UDP-glucose dehydrogenase의 활성도를 증가시켰다. 그러나...
152.

산소유리라디칼이 뇌조직 미크로좀분획의 Na+-K+-ATPase 활성도에 미치는 영향

오세문(Sae Moon Oh)손영숙(Young Sook Son), 최길수(Kil Soo Choi), 임정규(Jung Kyoo Lim), 정명희(Myung Hee Chung) 대한약리학회 대한약리학잡지 14 Pages

대한약리학회 대한약리학잡지 1982, 제 18권 제 2호 1 1-14 (14 pages)

오세문(Sae Moon Oh)손영숙(Young Sook Son), 최길수(Kil Soo Choi), 임정규(Jung Kyoo Lim), 정명희(Myung Hee Chung) 저
...
- 4,300원
중추신경계의 혈관폐쇄 또는 충격손상에 의한 허혈병소에서 진행되는 병리적 변화에 산소유리라디칼이 중요한 역할을 할 것으로 시사되고 있다. 저자는 산소유리라디칼이 뇌조직에 미치는 영향 중 특히 신경세포 정지막전위 유지에 중요한 Na+-K+-ATPase의 활성도에 미치는 영향을 관찰하기 위하여 산틴산화효소 반응계와 뇌조직미크로좀을 이용하여 본 연구를 시행하였다. 미크로좀분획(microsomal fraction)을 산틴과 산틴산화효소와 함께 반응시켰을 때, 분획의 Na+-K+-ATPase의 활성도는 현저한 불활성화를 보인 반면, Mg++-ATPase의...
153.

Phorbol Ester-Induced Periodic Contraction in Isolated Rabbit Jugular Vein

Ryu, Jae-Cheol, Jung, Dong-Keun, Lee, Sang-Ho 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 4 225-232 (8 pages)

Ryu, Jae-Cheol, Jung, Dong-Keun, Lee, Sang-Ho 저
...
- 3,000원
The present study was conducted to evaluate the effect of phorbol 12,13-dibutyrate (PDBu) on the contraction of rabbit jugular vein in vitro. PDBu concentrations of greater than 10 nM induced a periodic contraction which was composed of rapid contraction, plateau and slow relaxation. The frequency of periodic contraction increased as PDBu concentration increased. The PDBu-induced contraction was inhibited by staurosporine (100 nM), it was not changed by tetrodotoxin (1 μM). In Ca2+-free...
154.

Effects of Lemakalim, a Potassium Channel Opener, on the Contractility and Electrical Activity of the Antral Circular Muscle in Guinea-Pig Stomach

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 4 37-50 (14 pages)

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 저
...
- 4,300원
Synthetic potassium channel openers (KCOs) are agents capable of opening K-channels in excitable cells. These agents are known to have their maximal potency in the smooth muscle tissue, especially in the vascular smooth muscle. Much attention has been focused on the type of K-channel that is responsible for mediating the effects of KCOs. As the KCO-induced changes are antagonized by glibenclamide, an KATP (ATP-sensitive K-channel) blocker in the pancreatic β-cell, KATP was suggested to be the...
155.

Effect of Various Divalent Ions on the Calcium Current of Adrenal Medullary Chromaffin Cells in the Rat

Kim, Jun, Leem, Chae-Hun, Kim, Sang-Jeong 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 2호 2 113-122 (10 pages)

Kim, Jun, Leem, Chae-Hun, Kim, Sang-Jeong 저
...
- 3,000원
It is well known that chromaffin cells of adrenal medulla secrete catecholamine in response to sympathetic nerve activation and the influx of Ca2+ through the voltage dependent Ca2+ channels (VDCC) in the cell membrane do a major role in this secretory process. In this study, we explored the effect of divalent cations on VDCC of rat chromaffin cells. Rat (Sprague-Dawley rat, 150-250 gm) chromaffin cells were isolated and cultured. Standard giga seal, whole cell recording techniques were employed...
156.

A Novel Therapeutic Measure for Metabolic Acidosis with Amino Acids

Kim, Jun, Goo, Yong-Sook, Kim, Sang-Jeong, Park, Sang-Chul, Koh, Chang-Soon 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 1호 9 89-98 (10 pages)

Kim, Jun, Goo, Yong-Sook, Kim, Sang-Jeong, Park, Sang-Chul, Koh, Chang-Soon 저
...
- 3,000원
In hypoxic tissue conditions, pyruvate can not enter the Krebs cycle and lactic acid, produced from pyruvate, accumulates to induce lactic acidosis. Pyruvate, However, can also be converted to alanine by glutamate pyruvate transaminase, that could be enhanced by glutamate. Therefore, it would be a fundamental measure to treat the lactic acidosis in tissue hypoxic conditions when one can convert the accumulated lactic acid, through pyruvate, to alanine. To test the above hypothesis, we induced a...
157.

Physiology is Not an Appendage of Anatomy Illustrated with Deterministic Chaos -Annual Review Lecture, October 11, 1991-

Partridge, Lloyd D. 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 1호 1 1-14 (14 pages)

Partridge, Lloyd D. 저
...
- 4,300원
158.

Mechanisms of Contraction Induced by Sodium Depletion in the Rabbit Renal Artery

Kim, Se-Hoon, Chang, Seok-Jong, 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1991, 제 25권 제 2호 6 159-170 (12 pages)

Kim, Se-Hoon, Chang, Seok-Jong, 저
...
- 4,100원
In the rabbit renal artery, mechanisms of contraction by sodium depletion were investigated. The helical strips of isolated renal artery were immersed in the Tris-buffered salt solution. The contractions were recorded isometrically using a strain-gauge transducer. Na-free solution (Na was substituted by Li, choline or sucrose) produced contractions which were dependent on the nature of the Na substitutes. Na-free solution (choline) produced the contraction in ouabain-pretreated artery (Na loaded...
159.

Calcium Balance in the Heart -Annual Review Lecture, October 13, 1990-

Noble, Denis 대한생리학회 대한생리학회지 16 Pages

대한생리학회 대한생리학회지 1991, 제 25권 제 1호 1 1-16 (16 pages)

Noble, Denis 저
...
- 4,500원
160.

내측 편도핵의 위산분비 촉진작용에서 미주신경의 역할

김명석(Kim, Myung-Suk), 조양혁(Jo, Yang-Hyeok), 윤신희(Yoon, Shin-Hee), 한상준(Hahn, Sang-June), 이덕주(Rhie, Duck-Joo), 김정진(Kim, Chung-Chin) 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1989, 제 23권 제 2호 14 393-400 (8 pages)

김명석(Kim, Myung-Suk), 조양혁(Jo, Yang-Hyeok), 윤신희(Yoon, Shin-Hee), 한상준(Hahn, Sang-June), 이덕주(Rhie, Duck-Joo), 김정진(Kim, Chung-Chin) 저
...
- 3,000원

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