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Contractile Effects of Hemoglobin-Free Human Cerebrospinal Fluid on Isolated Porcine Cerebral Arteries
YungHongBaik, SeonYoungKang, HyunKook, SangKeunChyung, YoungJohngKook, SamSukKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 7 193-199 (7 pages)
elucidate the mechanism involved in the cerebral vascular spasm following subarachnoid hemorrhage (SAH), the effects of the cerebrospinal fluid (CSF) obtained from the SAH patients on the resting tension and its influence on the contractile responses to various vasoactive agents and to hypoxia were investigated in isolated porcine cerebral arteries. All the CSFs containing hemoglobin (Hb) produced contraction and some Hb-free CSFs also elicited contraction. When the Hb-free CSF was separated by... -
Influence of Glucocorticoids on Cholinergic Stimulation-Induced Catecholamine Secretion from the Rat Adrenal Medulla
Dong-YoonLim, Jae-JoonLee, Oh-SeongGweon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 5 173-184 (12 pages)
The present study was undertaken to examine the influence of glucocorticoids on the secretory responses of catecholamines (CA) evoked by acetylcholine (ACh), DMPP, McN-A-343, excess K+ and Bay-K-8644 from the isolated perfused rat adrenal gland and to clarify the mechanism of its action. The perfusion of the synthetic glucocorticoid dexamethasone (10-100 ՌM) into an adrenal vein for 20 min produced a dose-dependent inhibition in CA secretion evoked by ACh (5.32 mM), excess K+ (a... -
타액분비 및 선혈류 조절에 대한 내인성 산화질소의 역할
김원재, 남상채, 김미원 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 22 809-816 (8 pages)
vasodilation and salivation induced by chorda stimu1ation or administration of various vasodilators were examined in anesthetized cats. Effect of L-NAME on K+ efflux induced by carbachol was also examined using the excised submandibular slice in vitro. In the submandibular slices, acetylcholine(lO 5 molfL) or vasoactive intestinal polypeptide(VIP, 10 5 molfL) increased N02 contents, which was prevented by pretreatment with L-NAME. Salivary secretion in response to the chorda stimulation(3 V,... -
기관근의 수축성에 대한 말초성 Benzodiazepine 수용체의 역할
류한영, 최형철, 최은미, 손의동, 이광윤, 김원준, 하정희 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 18 769-774 (6 pages)
Involvement of Peripheral Benzodiazepine Receptor on the Contractility of Canine Trachealis Muscle. Han Young Rhyu\ Hyung Cheol Choi, Eun Mee Choi, Uy Dong Sohn, Kwang Youn Lee, Won Joon Kim, and Jeoung Hee Ha Department of Phannacology, College of Medicine, Yeungnam University, Taegu 705-035 and lDepartment of Chest Surgery, College of Medicine, Ajou University, Suwon 422- 849, Korea -
비-혈관평활근에서 새로운 K+ 동로 개방제인 SKP-450의 약리 학적 작용의 특성 -Levcromakalim의 작용과 비 교
홍기환, 박지영, 김현희, 유성은 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 17 759-767 (9 pages)
In Vitro Pharmacological Characteristics of SKP-450, A Novel K+ Channel Opener, in Non-Vascular Smooth Muscles in Comparison with Levcromakalim. Ki Whan HongI, Ji Young Park\ Hyun Hee Kim\ and Sung-Eun Y002 lDepartment of Pharmacology, College of Medicine, Pusan National University, Pusan, 602-739; and 2Korea Research Institute of Chemical Technology, Daejeon, Korea In the present study, we characterized the non-vascu1ar smooth musc1e relaxant effects of a novel benzoyran derivative,... -
Effect of UV Irradiation and Rebamipide on the Blood Flow and Viability of Rabbit Skin Flap
Eung-JooSuh, Hyoung-ChulChoi, Uy-DongSohn, Jeoung-HeeHa, Kwang-YounLee, Won-JoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 14 581-589 (9 pages)
This study was undertaken to examine the effects of ultraviolet light (UVL) and rebamipide on the cutaneous blood flow and tissue survival on rabbit skin flap. In a random bipedicle flap, Laser Doppler Flowmetry (LDF) was employed to measure the blood flow of flap (BFF). Wound Margin Strength (WMS) measured by force transducer and Light microscophy were used for evaluation of tissue viability. Single exposure to UVL increased the BFF gradually for more than 15 hours, and decreased the... -
Nitric Oxide Prevents the Bovine Cerebral Endothelial Cell Death Induced by Serum-Deprivation
ChulHoonKimYoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 6 515-521 (7 pages)
by serum- deprivation in bovine cerebral endothelial cells in this study. Addition of TNFα, which are inducer of iNOS, prevented serum-deprivation induced cell death. Increased expression of iNOS was confirmed indirectly by nitrite measurement. When selective iNOS inhibitors were treated, the protective effect of TNFα on cell death was partially blocked, suggesting that iNOS expression was involved in controlling cell death. Exogenously added NO substrate (L-arginine) and NO donors (sodium... -
신경세포가 별아교세포의 아교섬유성 산단백질 표현에 미치는 영향 Effect of Glial-neuronal Cell Co-culture on GFAP Expression of Astrocytes
배형미, 박정선, 연동수, HyungmiBae, JungsunPark, DongsooYeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.3 7 285-296 (12 pages)
strong GFAP and vimentin. In Western blot analysis, total GFAP and vimentin contents in co-cultured astrocytes were lower than those of primary cultured astrocytes. After glutamate exposure of glial-neuronal co-culture, GFAP and vimentin contents in astrocytes were increased to the level of primary cultured astrocytes. These results suggest that neuronal cell decrease GFAP expression in co-cultured astrocytes and hippocampal neuronal-glial co-culture can be used as a reactive gliosis model in... -
일측 전정기관 손상 흰쥐에서 동측의 내측 전정신경핵 활동성에 대한 전정기관의 전기자극 효과
이문영, 김민선, 박병림 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.3 5 263-273 (11 pages)
6 and 24 hours in rats receiving ULX. After ES, animals that showed the recovery of vestibular symptoms by counting and comparing the number of spontaneous nystagmus were selected for recording resting activity of type 1, 11 neurons in the medial vestibular nuclei (MVN) of the lesioned side. And then the dynamic neuronal activities were recorded during sinusoidal rotation at a frequency of 0.1 Hz and 0.2 Hz. The number of spontaneous nystagmus was significantly different 24 hours (p< 0.01) of... -
Platelet-Activating Factor Enhances Interleukin-1 Activity by Alveolar Macrophages Inhibition by PAF Specific Receptor Antagonists
JiheeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 10 201-208 (8 pages)
of mediators generated and released from activated phagocytes. In this study, the effect of PAF on interleukin-1(IL-1) activity by rat alveolar macrophages(AM) was examined using thymocyte proliferation assay in the supernate of sample obtained after 24 hr culture. When AM were cultured with PAF alone, no change in IL-1 activity was observed. However, the combined addition of PAF and muramyl dipeptide(MDP) or lipopolysaccharide(LPS) to AM cultures markedly enhanced IL-1 activity by 2-3 fold...


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