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201.

Pharmacological Action Mechanism(s) of Vasodilator Effect of Calcitonin Gene-related Peptide in Rat Basilar Arteries

임병용(Byung Yong Rhim), 홍선화(Sun Hwa Hong), 김치대(Chi Dae Kim), 이원석(Won Suk Lee), 김동헌(Dong Heon Kim), 홍기환(Ki Whan Hong) 대한약리학회 대한약리학잡지 12 Pages

대한약리학회 대한약리학잡지 1996, 제 32권 제 1호 5 39-50 (12 pages)

임병용(Byung Yong Rhim), 홍선화(Sun Hwa Hong), 김치대(Chi Dae Kim), 이원석(Won Suk Lee), 김동헌(Dong Heon Kim), 홍기환(Ki Whan Hong) 저
...
- 4,100원
did not exert any effect on the K+ (90 mM)-induced contraction and increase in [Ca2+]i, Further, [Ca2+]i-force relationships were determined by plotting the ratio of F340/F380 ([Ca2+]i) as a function of the force induced by U46619, and the results were compared with those obtained in the presence of CGRP. The curves obtained in the presence of CGRP (30 and 100 nM) were significantly moved to downward without right shift of the curves suggesting that CGRP inhibited the U46619-induced contraction...
202.

Cellular Mechanism of Nicotine-mediated Intracellular Calcium Homeostasis in Primary Culture of Mouse Cerebellar Granule Cells

김원기(Won-Ki Kim), 배영숙(Young-Sook Pae) 대한약리학회 대한약리학잡지 10 Pages

대한약리학회 대한약리학잡지 1996, 제 32권 제 1호 2 13-22 (10 pages)

김원기(Won-Ki Kim), 배영숙(Young-Sook Pae) 저
...
- 3,000원
involvement of glutamate in nicotine-mediated calcium responses. Fluorometric studies using fura-2 showed two phases of nicotine-evoked [Ca2+]i rises: the initial rising phase and the later plateau phase. Interestingly, the NMDA receptor antagonists and GPT appeared to inhibit only the later plateau phase of nicotine-evoked [Ca2+]i rises. The present results imply that nicotine mediated 45Ca2+ uptake and [Ca2+]i rises are attributed to the calcium fluxes through both nAchRs and NMDA receptors in...
203.

Effect of Ischemic Preconditioning on the Oxygen Free Radical Production in the Post-ischemic Reperfused Heart

박종완(Jong-Wan Park), 김영훈(Young-Hoon Kim), 엄창섭(Chang-Sub Uhm), 배재문(Jae-Moon Bae), 박찬웅(Chan-Woong Park), 김명석(Myung-Suk Kim) 대한약리학회 대한약리학잡지 10 Pages

대한약리학회 대한약리학잡지 1994, 제 30권 제 3호 6 321-330 (10 pages)

박종완(Jong-Wan Park), 김영훈(Young-Hoon Kim), 엄창섭(Chang-Sub Uhm), 배재문(Jae-Moon Bae), 박찬웅(Chan-Woong Park), 김명석(Myung-Suk Kim) 저
...
- 3,000원
The protective effect of ischemic preconditioning (PC) on ischemia-reperfusion injury of heart has been reported in various animal species, but without known mechanisms in detail. In an attempt to investigate the cardioprotective mechanism of PC, we examined the effects of PC on the myocardial oxidative injuries and the oxygen free radical production in the ischemia-reperfusion model of isolated Langendorff preparations of rat hearts. PC was performed with three episodes of 5 min ischemia and...
204.

Evidence for Excitatory Input to Ventral Spinocerebellar Tract Neurons Mediated by Motoneuron Collaterals

Kim, Jong-Hwan, Shim, Dae-Moo 대한생리학회 대한생리학회지 70 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 12 117-186 (70 pages)

Kim, Jong-Hwan, Shim, Dae-Moo 저
...
- 9,900원
This study evaluated the hypothesis that motoneuron collaterals modulate the excitability of ventral spinocerebellar tract neurons. In acute cats, 128 ventral cerebellar tract cells were studied extracellularly to determine the effects of ventral root stimuli. The majority of the cells responded to ventral root stimulation with either short or long latency increases in spike discharge. In many cells with sufficient spontaneous activity ventral root stimulation also evoked a long lasting...
205.

Effect of Blood Pressure on the Endothelium-Dependent Contraction in Rat Aorta

Jeon, Byeong-Hwa, Kim, Hoe-Suk, Kim, Se-Hoon, Chang, Seok-Jong 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 3 21-32 (12 pages)

Jeon, Byeong-Hwa, Kim, Hoe-Suk, Kim, Se-Hoon, Chang, Seok-Jong 저
...
- 4,100원
To investigate the mechanisms of increased endothelium-dependent contraction by acetylcholine in hypertensive rats, the relationship between endothelium-dependent contraction by acetylcholine and blood pressure was studied in spontaneously hypertensive rats (SHR), one-kidney, one clip Goldblatt hypertension (1K,1C-GBH) rats, and Wistar-Kyoto rats (WKY). SHR were treated orally with enalapril or nicardipine in order to prevent development of hypertension or suppress the developed hypertension....
206.

Effect of Blood Pressure on Contractility of Vascular Smooth Muscle and Endothelium-Dependent Relaxation

Suh, Suk-Hyo, Park, Yee-Tae, Lee, Dong-Chul, Seo, Pil-Won, Kim, Ki-Whan 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 10 279-290 (12 pages)

Suh, Suk-Hyo, Park, Yee-Tae, Lee, Dong-Chul, Seo, Pil-Won, Kim, Ki-Whan 저
...
- 4,100원
which the blood pressures (BPs) of symmetric regions (right and left upper extremities) are significantly different and 2) to test the effect of BP per se on the contractility and endothelium-dependent relaxation of vascular smooth muscle. Rabbits were anesthetized with sodium pentobarbital and ventilated with room air via animal respirator. The transverse aorta was exposed through the left second intercostal space and the lumen of the aorta was narrowed partially by ligation using 3-0 silk and...
207.

Effect of Preconditioning Ischemia on Endothelial Dysfunction Produced by Ischemia-Reperfusion in Rabbit Coronary Artery

Suh, Suk-Hyo, Park, Yee-Tae, Kim, Woong-Heum, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 5 51-60 (10 pages)

Suh, Suk-Hyo, Park, Yee-Tae, Kim, Woong-Heum, Kim, Ki-Whan 저
...
- 3,000원
This study was designed to test whether or not 1) ischemia-reperfusion attenuates endothelium-dependent relaxation of coronary arteries and 2) preconditioning protects the arterial endothelium from ischemia-reperfusion injury. In anesthetized open chest rabbits, branches of the left circumflex artery were exposed to different combinations of the experimental conditions; ischemia (15 minutes), ischemia (15 minutes)-reperfusion (10 minutes), preconditioning ischemia, and pre-conditioning fellowed...
208.

Effect of Cyclic Nucleotides on Phorbol Ester-Induced Contraction in Rabbit Carotid Artery

Jung, Dong-Keun, Woo, Jae-Suk, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 4 39-50 (12 pages)

Jung, Dong-Keun, Woo, Jae-Suk, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 저
...
- 4,100원
contraction was relaxed by staurosporine, which suggests that PDBu-induced contraction is mediated by protein kinase C (PKC). 45Ca2+ uptake by rabbit carotid artery was increased by PDBu during depolarization, but not in control. Isoproterenol and sodium nitroprusside (SNP) relaxed phenylephrine-induced contraction. However, SNP but not isoproterenol relaxed the contraction induced by PDBu. Acetylcholine relaxed PDBu-induced contraction in the presence of the endothelium. 8-bromo-cyclic AMP, a...
209.

Effect of Cyclic GMP on the Calcium Current in Rabbit Ventricular Myocytes

Han, Jin, Leem, Chae-Hun, Ahn, Chul-Soo, So, In-Suk, Kim, Eui-Yong, Ho, Won-Kyung, Earm, Yung-E 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 2호 4 151-162 (12 pages)

Han, Jin, Leem, Chae-Hun, Ahn, Chul-Soo, So, In-Suk, Kim, Eui-Yong, Ho, Won-Kyung, Earm, Yung-E 저
...
- 4,100원
In order to investigate the effect of intracellular cyclic GMP on calcium current the whole-cell patch clamp technique with internal perfusion method was used in isolated ventricular myocytes of the rabbit. Cyclic GMP, 8-bromo-cyclic GMP, cyclic AMP, isoprenaline and forskolin were perfused into cells and their effects on calcium current were analysed by applying depolarizing step pulses of + 10 mV in amplitude far 300 msec from holding potential of - 40 mV. Not only cyclic AMP (100 μM) but...
210.

Effect of Dopamine on the Ca2+-dependent K+ currents in Isolated Single Gastric Myocytes of the Guinea-pig

Rhee, Poong-Lyul, Lee, Sang-Jin, Kim, Sung-Joon, So, In-Suk, Hwang, Sang-Ik, Kim, Ki-Whan 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 2호 3 139-150 (12 pages)

Rhee, Poong-Lyul, Lee, Sang-Jin, Kim, Sung-Joon, So, In-Suk, Hwang, Sang-Ik, Kim, Ki-Whan 저
...
- 4,100원
not changed by dopamine. 3) The voltage-operated inward Ca2+ current was not influenced by dopamine. 4) The Ca2+-dependent K+ outward current, which might reflect the changes of intracellular calcium concentration, was enhanced by dopamine. This effect was abolished by phentolamine. 5) The enhancing effect of dopamine on the Ca2+ -dependent K+ current disappeared with heparin which is known to block the action of InsP3. From these results, it is suggested that dopamine acts via InsP3-mediated...

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