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Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis
Ju-HyungPark, GeunMookPark, Jin-KyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 5 335-340 (6 pages)
Here, we investigated the role of zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, on angiogenesis using human umbilical vein endothelial cells (HUVECs). Zerumbone inhibited HUVECs proliferation, migration and tubule formation, as well as angiogenic activity by rat aorta explants. In particular, zerumbone inhibited phosphorylation of vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1, which are key regulators of endothelial cell function... -
Low Non-NMDA Receptor Current Density as Possible Protection Mechanism from Neurotoxicity of Circulating Glutamate on Subfornical Organ Neurons in Rats
WoneeChong, SeongNamKim, SeongKyuHan, SoYeongLee, PanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 13 177-181 (5 pages)
The subfornical organ (SFO) is one of circumventricular organs characterized by the lack of a normal blood brain barrier. The SFO neurons are exposed to circulating glutamate (60∼100 μM), which may cause excitotoxicity in the central nervous system. However, it remains unclear how SFO neurons are protected from excitotoxicity caused by circulating glutamate. In this study, we compared the glutamate-induced whole cell currents in SFO neurons to those in hippocampal CA1 neurons using the patch... -
The Stimulatory Effect of Essential Fatty Acids on Glucose Uptake Involves Both Akt and AMPK Activation in C2C12 Skeletal Muscle Cells
SoYeonPark, MinHyeKim, JoungHoonAhn, SuJinLee, JongHoLee, WonSikEum, SooYoungChoi, HyeokYilKwon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.3 9 255-261 (7 pages)
of its downstream molecules, acetyl-CoA carboxylase (ACC) was markedly induced by EFA, but not OA. In addition, EFA-stimulated 2-NBDG uptake was significantly inhibited by the pre-treatment of a specific AMPK inhibitor, adenine 9-β-D-arabinofuranoside (araA). These data suggest that the restoration of suppressed insulin signaling at PA-induced insulin resistant condition and AMPK activation are involved at least in the stimulatory effect of EFA on glucose uptake in C2C12 skeletal muscle cells. -
p66shc Adaptor Protein Suppresses the Activation of Endothelial Nitric Oxide Synthase in Mouse Embryonic Fibroblasts
SangKiLee, YoungShinKim, CukSeongKim, SookJinSon, DaeGoonYoo, KwonHoLee, SangDoLee, JinBongPark, ByeongHwaJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.3 7 155-160 (6 pages)
Among the Shc proteins, p66shc is known to be related to oxidative stress responses and regulation of the production of reactive oxygen species (ROS). The present study was undertaken to investigate the role of p66shc on endothelial nitric oxide synthase (eNOS) activity in the mouse embryonic fibroblasts (MEFs). When wild type (WT) or p66shc (/) MEFs were transfected with full length of eNOS cDNA, the expression and activity of eNOS protein were higher in the p66shc... -
한국 일반 인구에 있어 식사특성, 성격특징 및 기타 정신병리의 상관관계에 대한 연구
이영호, 이민규, 박세현, 손창호, 정영조, 홍성국, 이병관, 장필립, 윤애리 대한신경정신의학회 신경정신의학 17 Pages
대한신경정신의학회 신경정신의학 1999, 제 38권 제 1호 6 77-93 (17 pages)
연구목적: 한국 일반 인구를 대상으로 식사특성과 성격특징간의 상관관계와, 우울경향성 및 건강염려증 경향성과 식 사특성 그리고 성격특징간의 상관관계를 알아 보아 1) 식사 장애의 문제가 성격 장애의 문제와 마찬가지로 병리의 정도에 따라 연속성을 보이는 일련선상의 문제이며, 2) 성격의 특징 중 특정한 성격특징이 식사특성 상의 문제 즉, 식사 장애에 특이한 핵심 병리의 형성과 직접 관련이 있고, 3) 우울경향이나 건강염려증과 같 은 비특이적인 일반 정신병리는 다른 성격 특징과의 상호작용을 통해 식사 문제를... -
수온변화와 Epinephrine에 의한 자라의 심맥관계 및 신장기능의 변화
김선희(Kim, Suhn-Hee), 조경우(Cho, Kyung-Woo), 설경환(Seul, Kyung-Hwan), 고규영(Koh, Gou-Young) 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1987, 제 21권 제 2호 5 201-210 (10 pages)
수온변화에 따른 심맥관계 및 신장기능의 변화와 생체실험을 통한 온도에 의한 adrenoceptor의 변형을 알아보기 위해, 무마취 자라에서 18℃에서 25℃로 수온을 증가시 나타나는 혈압, 심박동수 및 신장기능의 변화를 관찰하고, epinephrine 1 ug/kg과 10 ug/kg을 상이한 온도에 노출된 자라의 정맥내 투여하여 나타나는 효과를 비교하였다. 1) 18℃에서 25℃로 수온을 증가시킴에 따라 심박동수는 현저히 증가하여 일정하게 유지되었으나, 혈압 및 혈장 renin 활성도는 변화하지 않았다. 온도증가에 의해 뇨량, 사구체여과율 및 전해질... -
IsIsolation and Characterization of Airborne Mushroom Damaging Trichoderma spp. from Indoor Air of Cultivation Houses Used for Oak Wood Mushroom Production Using Sawdust Mediaolation and Characterization of Airborne Mushroom Damaging Trichoderma spp. from
Jun Young Kim, Hyuk Woo Kwon, Dong Hyeung Lee, Han Kyu Ko, Seong Hwan Kim 한국식물병리학회 The Plant Pathology Journal 10 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 6호 13 674-683 (10 pages)
Some species of the Trichoderma genus are reported as the major problem in oak wood mushroom production in Korea. In spite of economic loss by the fungi, scientific information on airborne Trichoderma species is not much available. To generate information for disease management development we analyzed airborne Trichoderma. A total of 1,063 fungal isolates were purely obtained from indoor air sampling of cultivation houses used for oak wood mushroom using sawdust media. Among the obtained... -
Pathogenic Diversity of Ascochyta rabiei Isolates and Identification of Resistance Sources in Core Collection of Chickpea Germplasm
Somayeh Farahani, Reza Talebi, Mojdeh Maleki, Rahim Mehrabi, Homayoun Kanouni 한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 4호 4 321-329 (9 pages)
Ascochyta blight caused by Ascochyta rabiei (Pass.) Lab. (Telomorph: Didymella rabiei) (Kov.) is one of the most important fungal diseases in chickpea worldwide. Knowledge about pathogen aggressiveness and identification resistance sources to different pathotypes is very useful for proper decisions in breeding programs. In this study, virulence of 32 A. rabiei isolates from different part of Iran were analyzed on seven chickpea differentials and grouped into six races based on 0-9 rating scale... -
Efficacy of Newer Molecules, Bioagents and Botanicals against Maydis Leaf Blight and Banded Leaf and Sheath Blight of Maize
한국식물병리학회 The Plant Pathology Journal 5 Pages
한국식물병리학회 The Plant Pathology Journal 2018, 34권 2호 5 121-125 (5 pages)
of chemicals, botanicals and bioagents for the management of MLB and BLSB under field condition for two seasons Kharif 2014 and 2015. Five molecules (propiconazole 25 EC, hexaconazole 25 EC, carbendazim 50 WP, mancozeb 75 WP and carbedazim 12 WP + mancozeb 63 WP), two bioagents i.e. Trichoderma harzianum and T. viridae and three botanicals namely azadirachtin, sarpagandha and bel pathar were tested for their efficacy against MLB. Eight newer fungicides viz., difenconazole 250 SC, hexaconazole 5... -
Inheritance of Pigeonpea Sterility Mosaic Disease Resistance in Pigeonpea
한국식물병리학회 The Plant Pathology Journal 7 Pages
한국식물병리학회 The Plant Pathology Journal 2014, 30권 2호 10 188-194 (7 pages)
A comprehensive study was conducted using PPSMV resistant (BSMR 736) and susceptible (ICP 8863) genotypes to develop a segregating population and understand the inheritance of PPSMV resistance. The observed segregation was comparable to 13 (susceptible): 3 (resistant). Hence, the inheritance was controlled by two genes, SV1 and SV2, with inhibitory gene interaction.


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