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211.

Effect of the Inhibition of PLA2 on Oxidative Lung Injury Induced by Interleukin-1㄁

YoungManLee, HyunGugCho, Yoon-YubPark, Jong-KiKim, YoonJeongLee, Won-HarkPark, TeoanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 10 617-628 (12 pages)

YoungManLee, HyunGugCho, Yoon-YubPark, Jong-KiKim, YoonJeongLee, Won-HarkPark, TeoanKim 저
...
- 4,100원
In order to understand the pathogenetic mechanism of adult respiratory distress syndrome (ARDS), the role of phospholipase A2 (PLA2) in association with oxidative stress was investigated in rats. Interleukin-1㄁ (IL-1, 50 ㄍg/rat) was used to induce acute lung injury by neutrophilic respiratory burst. Five hours after IL-1 insufflation into trachea, microvascular integrity was disrupted, and protein leakage into the alveolar lumen was followed. An infiltration of neutrophils was...
212.

Increased Activity of Large Conductance Ca2+-Activated K+ Channels in Negatively-Charged Lipid Membranes

JinBongParkPanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 15 529-539 (11 pages)

JinBongParkPanDongRyu 저
...
- 4,000원
a distance of 8∼9 Å from the membrane surface. In addition, similar insulation distance (7∼9 Å) of channel mouth from the bilayer surface charge was predicted by a 3-barrier-2-site model of energy profile for the permeation of K⁢ ions. In conclusion, despite the differences in structure and fluidity of phospholipids in bilayers, the activities of maxi K channels in two charged membranes composed of PS or PI were strikingly similar and larger than those in bilayers of PE. These results...
213.

Protective Mechanism of Nitric Oxide and Mucus against Ischemia/ Reperfusion-Induced Gastric Mucosal Injury

HyeyoungKim, KwangsooNam, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 13 511-519 (9 pages)

HyeyoungKim, KwangsooNam, KyungHwanKim 저
...
- 3,000원
This study investigated the role of nitric oxide on the oxidative damage in gastric mucosa of rats which received ischemia/reperfusion and its relation to mucus. Nitric oxide synthesis modulators such as L-arginine and NG-nitro-L-arginine methyl ester, and sodium nitroprusside, a nitric oxide donor, were injected intraperitoneally to the rats 30 min prior to ischemia/reperfusion which was induced by clamping the celiac artery and the superior mesenteric artery for 30 min and reperfusion for 1...
214.

Comparison of Inodilator Effect of Higenamine, YS49, YS51, Tetrahydroisoquinoline Analogs, and Dobutamine in the Rat

Won-SeogChong, Young-SooLee, Young-JinKang, Duck-HyungLee, Jae-ChunRyu, HyeSookYun-Choi, Ki-ChurlChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 7 323-330 (8 pages)

Won-SeogChong, Young-SooLee, Young-JinKang, Duck-HyungLee, Jae-ChunRyu, HyeSookYun-Choi, Ki-ChurlChang 저
...
- 3,000원
Tetrahydroisoquinoline (THI) alkaloids can be considered as cyclized derivatives of simple phenylethylamines. Many of them, especially with 6,7-disubstitution, demonstrate a relatively high affinity for catecholamines. Present study examines the pharmacological action of limited series of THI, using rats' isolated atria and aorta. In addition, a [3H] prazosin displacement binding study with THI compounds was performed, using rat brain homogenates to investigate whether these probes have...
215.

Comparison of Somatostatin and Morphine Action on the Responses of Wide Dynamic Range Cells in the Dorsal Horn to Peripheral Noxious Mechanical and Heat Stimulation in Cats

SungJunJung, YoungInChoi, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 3 155-163 (9 pages)

SungJunJung, YoungInChoi, JunKim 저
...
- 3,000원
The purpose of present study was to compare the effects of somatostatin (SOM) and morphine (Mor) on the responses of wide dynamic range (WDR) cells to peripheral noxious stimulation. Single neuronal activity was recorded with a carbon-filament electrode at the lumbosacral enlargement of cat spinal cord. After identifying WDR cells, their responses to peripheral noxious mechanical or thermal stimuli were characterized and the effects of SOM and Mor, applied either iontophoretically or...
216.

Ca2+ Signalling in Endothelial Cells Role of Ion Channels

BerndNilius, FelixViana, MasahiroKamouchi, CristinaFasolato, JanEggermont, GuyDroogmans 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 1 133-145 (13 pages)

BerndNilius, FelixViana, MasahiroKamouchi, CristinaFasolato, JanEggermont, GuyDroogmans 저
...
- 4,200원
217.

Effect of UV Irradiation and Rebamipide on the Blood Flow and Viability of Rabbit Skin Flap

Eung-JooSuh, Hyoung-ChulChoi, Uy-DongSohn, Jeoung-HeeHa, Kwang-YounLee, Won-JoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 14 581-589 (9 pages)

Eung-JooSuh, Hyoung-ChulChoi, Uy-DongSohn, Jeoung-HeeHa, Kwang-YounLee, Won-JoonKim 저
...
- 3,000원
This study was undertaken to examine the effects of ultraviolet light (UVL) and rebamipide on the cutaneous blood flow and tissue survival on rabbit skin flap. In a random bipedicle flap, Laser Doppler Flowmetry (LDF) was employed to measure the blood flow of flap (BFF). Wound Margin Strength (WMS) measured by force transducer and Light microscophy were used for evaluation of tissue viability. Single exposure to UVL increased the BFF gradually for more than 15 hours, and decreased the...
218.

Effect of Panax ginseng on Latency of Passive Avoidance Response and Neuronal Damage of Hippocampus

So-HyunCho, Sang-HyunChoi, Jae-WonChoi, Dong-HoonKim, Kyung-HoShin, Yeon-SookChun, Boe-GwunChun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 1 345-353 (9 pages)

So-HyunCho, Sang-HyunChoi, Jae-WonChoi, Dong-HoonKim, Kyung-HoShin, Yeon-SookChun, Boe-GwunChun 저
...
- 3,000원
The effects of crude saponin (SAP) and alkaloid (ALK) fractions of Panax ginseng C.A. Meyer on the detrimental effects of electroconvulsive shock (ECS) and scopolamine on passive avoidance response (PAR) were studied in male Sprague-Dawley rats, referring their effects on the neuronal injury and plasticity of hippocampus in response to electrolytic lesion of left entorhinal cortex (ECL). The detrimental ECS effect on PAR was attenuated by pre- and post-treatments with SAP and ALK, respectively,...
219.

Platelet-Activating Factor Enhances Interleukin-1 Activity by Alveolar Macrophages Inhibition by PAF Specific Receptor Antagonists

JiheeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 10 201-208 (8 pages)

JiheeLee 저
...
- 3,000원
It is becoming increasingly clear that the inflammatory reaction can be ascribed to a complex array of mediators generated and released from activated phagocytes. In this study, the effect of PAF on interleukin-1(IL-1) activity by rat alveolar macrophages(AM) was examined using thymocyte proliferation assay in the supernate of sample obtained after 24 hr culture. When AM were cultured with PAF alone, no change in IL-1 activity was observed. However, the combined addition of PAF and muramyl...
220.

Effect of Hemorrhage on mRNA Expressions of Renin, Angiotensinogen and AT1 Receptors in Rat Central and Peripheral Tissues

MiKyungLee, HakryulJo, Kyung-SoonKim, Eun-KyoungYang, Won-JungLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 5 151-159 (9 pages)

MiKyungLee, HakryulJo, Kyung-SoonKim, Eun-KyoungYang, Won-JungLee 저
...
- 3,000원
In an attempt to investigate whether hemorrhage affects the gene expression of the renin-angioteusin system (RAS) components in the brain and peripheral angiotensin-generating tissues, changes in mRNA levels of the RAS components in response to hemorrhage were measured in conscious unrestrained rats. Wistar rats were bled at a rate of 3 ml/kg/min for 5 min, and then decapitated 7 h after hemorrhage. Levels of mRNA for renin, angiotensinogen and angiotensin II-AT1 receptor subtypes (AT1A and...

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