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211.

Effect of Prostaglandins D2, E2 and I2 on the Regulation of KATP Channel Activity in Rat Cardiac Myocytes

Jeong-MinJu, Seung-YeolNah, Jae-HaKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 7 507-512 (6 pages)

Jeong-MinJu, Seung-YeolNah, Jae-HaKim 저
...
- 3,000원
ATP-sensitive K⁢ channel (KATP channel) was investigated in isolated single rat ventricular cardiac myocytes using the patch clamp technique. PGD2, PGE2 and PGI2 did not affect KATP channel activity in the inside-out patch, but increased channel activity in a dose-dependent manner when the channel activities were attenuated by the administration of 100 μM ATP to the internal solution in the inside-out patch. Channel activations by the prostaglandins were abolished by 50 μM glibenclamide,...
212.

Temporal Changes in Neuronal Activity of the Bilateral Medial Vestibular Nuclei Following Unilateral Labyrinthectomy in Rats

ByungRimPark, MoonYoungLee, MinSunKim, SungHoLee, HanJoNa, NamYongDoh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 4 481-490 (10 pages)

ByungRimPark, MoonYoungLee, MinSunKim, SungHoLee, HanJoNa, NamYongDoh 저
...
- 3,000원
To investigate the changes in the responses of vestibular neurons with time during vestibular compensation, the resting activity and dynamic responses of type I and II neurons in the medial vestibular nuclei to sinusoidal angular acceleration were recorded following unilateral labyrinthectomy (ULX) in Sprague-Dawley rats. The unitary extracellular neuronal activity was recorded from the bilateral medial vestibular nuclei with stainless steel microelectrodes of 3∼5 MΩ before ULX, and 6, 24,...
213.

Effects of Carnosine and Related Compounds on Monosaccharide Autoxidation and H2O2 Formation

BeomJunLee, KyungSunKang, SangYoonNam, JaeHakPark, YongSoonLee, YoungWonYun, MyungHaingCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 3 251-261 (11 pages)

BeomJunLee, KyungSunKang, SangYoonNam, JaeHakPark, YongSoonLee, YoungWonYun, MyungHaingCho 저
...
- 4,000원
The effects of carnosine and related compounds (CRCs) including anserine, homocarnosine, histidine, and β-alanine on monosaccharide autoxidation and H2O2 formation were investigated. The incubation of CRCs with D-glucose, D-glucosamine, and D, L-glyceraldehyde at 37oC increased the absorption maxima at 285 nm, 273 nm, and 290∼330 nm, respectively. D, L-glyceraldehyde was the most reactive sugar with CRCs. The presence of copper strongly stimulated the reaction of carnosine and anserine with...
214.

Magnesium Suppresses the Responses of Dorsal Horn Cell to Noxious Stimuli in the Rat

HongKeeShin, JinHyukKim, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 1 237-244 (8 pages)

HongKeeShin, JinHyukKim, KeeSoonKim 저
...
- 3,000원
Magnesium ion is known to selectively block the N-methyl-D-aspartate (NMDA)-induced responses and to have anticonvulsive action, neuroprotective effect and antinociceptive action in the behavioral test. In this study, we investigated the effect of Mg2⁢ on the responses of dorsal horn neurons to cutaneous thermal stimulation and graded electrical stimulation of afferent nerves as well as to excitatory amino acids and also elucidated whether the actions of Ca2⁢ and Mg2⁢ are...
215.

Regulation of Magnesium Release by cAMP during Chemical Hypoxia in the Rat Heart and Isolated Ventricular Myocytes

JinShangKimAntonioScarpa 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 8 59-68 (10 pages)

JinShangKimAntonioScarpa 저
...
- 3,000원
Chemically induced hypoxia has been shown to induce a depletion of ATP. Since intracellular free Mg2⁢ ([Mg2⁢]i) appears to be tightly regulated following cellular energy depletion, we hypothesized that the increase in [Mg2⁢]i would result in Mg2⁢ extrusion following hormonal stimulation. To determine the relation between Mg2⁢ efflux and cellular energy state in a hypoxic rat heart and isolated myocytes, [Mg2⁢]i, ATP and Mg2⁢ content were measured by...
216.

The Effects of Intracellular Monocarboxylates on the ATP-sensitive Potassium Channels in Rabbit Ventricular Myocytes

NariKim, JinHan, Eui-YongKim, Won-KyungHo, YungE.Earm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 6 581-589 (9 pages)

NariKim, JinHan, Eui-YongKim, Won-KyungHo, YungE.Earm 저
...
- 3,000원
or permeabilized attached (open-cell) patch-clamp technique at room temperature. Intracellular application of acetate, formate and pyruvate led to an inhibition of channel activity, whereas intracellular application of lactate increased channel activity. These effects were reversible upon washout. Analysis of single channel kinetics showed that monocarboxylates did not affect open-time constant and close-time constant. These results suggest that monocarboxylates participate in modulating KATP...
217.

Renal Handling of Sodium and Potassium in Cadmium Exposed Rats

YungKyuKimYangSaengPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 12 503-510 (8 pages)

YungKyuKimYangSaengPark 저
...
- 3,000원
exposure on renal Na⁢ and K⁢ transports were studied in rats. During the course of cadmium treatment (2 mg Cd/kg/day, s.c. injections for 3 weeks) renal tubular transports of Na⁢ and K⁢ were evaluated by lithium clearance technique. During the early phase (first week) of cadmium treatment, urinary Na⁢ excretion decreased drastically and this was due to an increased Na⁢ reabsorption both in the proximal and distal nephrons. During the late phase (third week) of...
218.

Altered Renal Nitric Oxide System in Experimental Hypertensive Rats

EunSukYang, JongUnLee, DaeGillKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 7 455-460 (6 pages)

EunSukYang, JongUnLee, DaeGillKang 저
...
- 3,000원
The present study was aimed at investigating whether the development of hypertension is related with an altered expression of nitric oxide synthases (NOS) in the kidney. By Western blot analysis, the expression of bNOS and ecNOS isoforms was determined in the kidney of deoxycorticosterone acetate (DOCA)-salt and two-kidney, one clip (2K1C) rats. In DOCA-salt hypertension, the expression of both bNOS and ecNOS was decreased, along with tissue contents of nitrites. In 2K1C hypertension, the...
219.

Effects of Prostaglandin E2 on the Spontaneous Contractions and Electrical Activities of the Antral Circular Muscle in Guinea-pig Stomach

JongYoonKim, SungJoonKim, TongMookKang, SangJinLee, JaeYeoulJun, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 11 361-368 (8 pages)

JongYoonKim, SungJoonKim, TongMookKang, SangJinLee, JaeYeoulJun, InsukSo, KiWhanKim 저
...
- 3,000원
an intracellular recording technique. To elucidate the underlying mechanism for its effect on contractility, ionic currents were also measured using a whole-cell patch clamp method. The basal tone by PGE2 was variable, whereas the magnitude of phasic contractions was reduced (19.0⁑2.1%, n=19). The resting membrane potentials were hyperpolarized (⁣4.4⁑0.5 mV, n=10), and plateau potentials were lowered (⁣2.9⁑0.5 mV, n=10). In most cases, however, the initial peak...
220.

Depression of Ca2+ Influx in Complement C5a-stimulated Neutrophils by Calmodulin Inhibitors

DongSukHam, HyunHoKim, EunSookHan, ChungSooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 14 109-117 (9 pages)

DongSukHam, HyunHoKim, EunSookHan, ChungSooLee 저
...
- 3,000원

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