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221.

Rat적출심방 운동성에 대한 Prostaglandin F2 alpha와 Ouabain작용의 비교

이광윤(Kwang Youn Lee) 대한약리학회 대한약리학잡지 11 Pages

대한약리학회 대한약리학잡지 1984, 제 20권 제 1호 7 55-65 (11 pages)

이광윤(Kwang Youn Lee) 저
...
- 4,000원
PGE2α의 rat적출심방에 대한 작용을 ouabain의 작용과 비교하여 다음과 같은 결과를 얻었다. PGE2α의 양성변력성작용은 ouabain의 작용에 비해 potency가 강하고 efficacy는 낮았다. Ouabain은 PGE2α의 양성변시성작용과 유사한 양성변시성 경향을 나타내었는데 이 점에 대해 추후의 탐구가 요구된다. PGE2α(3 × 10-8M)의 작용은 저칼슘농도(1.4mM)에서 ouabain(3 × 10-3M)보다 현저히 (≤0.05 ~ p≤0.00)강하게 나타났고, medium내에 첨가되는 Ca++에 대하여도 보다 예민하게 반응하였다. 저칼륨 medium(2.8mM) 또는 medium내...
222.

백서(白鼠) 뇌조직(腦組織)에서 Morphine의 Saturable Binding에 미치는 전해질(電解質)의 영향(影響)

고복현(Bok-Hyun Ko), 채수완(Soo Wan Chae), 조규박(Kyu Park Cho) 대한약리학회 대한약리학잡지 12 Pages

대한약리학회 대한약리학잡지 1982, 제 18권 제 2호 4 33-44 (12 pages)

고복현(Bok-Hyun Ko), 채수완(Soo Wan Chae), 조규박(Kyu Park Cho) 저
...
- 4,100원
전해질농도(電解質濃度)를 달리하고 morphine, naloxone 또는 morphine+naloxone을 가(加)하거나 가(加)하지 않은 modified Krebs-Henseleit bicarbonate buffer용액(溶液)에 흰쥐의 뇌절편(腦切片)을 incubate하여 저온처리(低溫處理)와 media내(內) 전해질조성(電解質組成)이 (3H)-morphine의 saturable binding에 미치는 영향(影響)을 관찰(觀察)하여 다음과 같은 성적(成績)을 얻었다. 1) 저온처리(低溫處理)는 (3H)-morphine의 saturable binding을 현저(顯著)히 증가(增加)시켰고, maximal saturable binding은 증가(增加)시키나...
223.

Enhanced Vasorelaxation Response to Cromakalim in Spontaneously Hypertensive Rats

Kim, Se-Hoon, Oh, Yeong-Seon, Kim, Hoe-Suk, Jeon, Byeong-Hwa, Chang, Seok-Jong 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 2 11-20 (10 pages)

Kim, Se-Hoon, Oh, Yeong-Seon, Kim, Hoe-Suk, Jeon, Byeong-Hwa, Chang, Seok-Jong 저
...
- 3,000원
and normotensive Wistar-Kyoto rats (WKY). 1. Cromakalim relaxed the aortic ring contracted by 10-7 M norepinephrine (NE) dose-dependently, and this relaxant response to cromakalim was blocked by 10-5 M glybenclamide. 2. Cromakalim also relaxed the contraction induced by high K+-solution or 10 mM tetraethylammonium dose-dependently. However, the relaxant response to cromakalim was decreased by raising the K+ concentration. 3. SHR aorta exhibited myogenic tone in resting state which was inhibited...
224.

Contractile and Electrical Responses of Guinea-pig Gastric Smooth Muscle to Bradykinin

Kim, Chul-Soo, Jun, Jae-Yeoul, Kim, Sung-Joon, So, In-Suk, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 5 233-242 (10 pages)

Kim, Chul-Soo, Jun, Jae-Yeoul, Kim, Sung-Joon, So, In-Suk, Kim, Ki-Whan 저
...
- 3,000원
a triphasic contractile response (transient contraction-transient relaxation-sustained contraction) and this response was unaffected by pretreatment with neural blockers (tetrodotoxin, atropine and guanethidine) or with apamin. Bradykinin induced hyperpolarization of resting membrane potential and enhanced the amplitude of slow waves and spike potentials. The enhancement of spike potentials was blocked by neural blockers. Both the bradykinin-induced contractions and changes in membrane potential...
225.

Effects of α1-Adrenergic Receptor Stimulation on Intracellular Na+ Activity and Twitch Force in Guinea-Pig Ventricular Muscles

Chae, Soo-Wan, Gong, Q.Y., Wang, D.Y., Lee, Chin-O. 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 2 203-216 (14 pages)

Chae, Soo-Wan, Gong, Q.Y., Wang, D.Y., Lee, Chin-O. 저
...
- 4,300원
The effects of α1-adrenergic receptor stimulation on membrane potential, intracellular Na+ activity, and twitch force were investigated in ventricular muscles from guinea-pig hearts. Action potentials, intracellular Na+ activity, and twitch force of ventricular papillary muscles were measured simultaneously under various experimental conditions. Stimulation of the α1-adrenergic receptor by phenylephrine produced variable changes in action potential duration, a slight hyperpolarization of the...
226.

The Action of Ginkgo Bibloba Extract in the Isolated Rabbit Corpus Cavernosum

Chung, Woo-Sik, Choi, Young-Deuk, Park, Young-Yo, Hah, Jong-Sik 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 6 61-68 (8 pages)

Chung, Woo-Sik, Choi, Young-Deuk, Park, Young-Yo, Hah, Jong-Sik 저
...
- 3,000원
of the smooth muscle endothelium or by pretreatment with a NO scavenger, pyrogallol (10-4 M) or the guanylate cyclase inhibitor, methylene blue (10-4 M). Pretreatment with EGb (3 mg/ml) inhibited PHE- (5 X 10-6 M) or KCI- (20 and 40 mM) induced contraction of muscle strip. In calcium-free high potassium solution EGb depressed the basal tone of the depolarized muscle strip and inhibited calcium-induced contraction when 2 (10-4 M) was added. These results suggest that EGb relaxes rabbit corpus...
227.

Properties of Single K+ Channels of Skeletal Muscle Incorporated into Planar Lipid Bilayer

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 대한생리학회 대한생리학회지 16 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 2 13-28 (16 pages)

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 저
...
- 4,500원
a prominent conductance substate. The first K+ channel was identified as the large Ca2+-activated K+ (BK) channel because the open-state probability was increased with depolarization (e-fold change per 10.6±3.5 mV, n=8) and internal Ca2+ (half-activation at 16.7±3.8 mV, n=8, pCa 4) and its conductance was large (247±4.9 pS, n=24 in 0.1 M KCI). Lifetime distributions of open- and closed-states could be fitted with single exponentials of several milliseconds. The mean open- and closed-lifetimes...
228.

Calcium Current in the Unfertilized Egg of the Hamster

Haan, Jae-Hee, Cho, Soo-Wan, Yang, Young-Sun, Park, Young-Geun, Park, Hong-Gi, Chang, Gyeong-Jae, Kim, Yang-Mi, Park, Choon-Ok, Hong, Se 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 12 215-224 (10 pages)

Haan, Jae-Hee, Cho, Soo-Wan, Yang, Young-Sun, Park, Young-Geun, Park, Hong-Gi, Chang, Gyeong-Jae, Kim, Yang-Mi, Park, Choon-Ok, Hong, Se 저
...
- 3,000원
specific channel was examined in the unfertilized hamster egg using the whole-cell voltage clamp technique. Pure inward current was isolated using a Ca2+-rich pipette solution containing 10 mM TEA. This current was independent of external Na+ and was highly sensitive to the Ca2+ concentration in the bathing solution, indicating that the inward current is carried by Ca2+. The maximal amplitude was -4.12±0.58nA (n=12) with 10mM Ca2+ at -3OmV from a holding potential of -8OmV. This current reached...
229.

Effect of pH on the Vascular Tone and 45Ca Uptake in the Aorta of Spontaneously Hypertensive Rats

Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Park, Hae-Kun 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 7 169-180 (12 pages)

Chang, Seok-Jong, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Park, Hae-Kun 저
...
- 4,100원
~ 8.3 was estimated by comparison with the level of vascular tone at pH 7.4. Contraction was induced below pHo 6.5 in WKY, pHo 7.1 in SHR, and over pHo 8.0 on both strains. The amplitude of contraction induced by high pHo (over pHo 7.7) was similar in SHR and WKY, but that induced by low pHo (below pHo 7.1) in SHR was greater than that in WKY. Either high pHo- or low pHo-induced contractions in WKY and SHR were not induced in the Ca-free Tyrode s solution and were induced by the addition of Ca....
230.

Role of Na+Ca2+ Exchange in the Control of Contractility in Rabbit Basilar Arterial Smooth Muscle

Kim Eui-Yong, Han Jin 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 6 159-168 (10 pages)

Kim Eui-Yong, Han Jin 저
...
- 3,000원
The contraction of rabbit basilar artery was examined as a function of changes in the Na+ electrochemical gradient in order to determine the contribution of Na+/Ca2+ exchange to the modulation of contractility. Ouabain (10-5 M) or K+-free Tyrode solution caused an increase in tonic tension even in the presence of a Ca2+ channel blocker (10-6 M verapamil) and an α-receptor blocker (10-5 M phentolamine). After treatment with ouabain (10-5 M), contractions were augmented by reduction of external...

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