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241.

Effects of High Glucose Levels on the Protein Kinase C Signal Transduction Pathway in Primary Cultured Renal Proximal Tubule Cells

Han, Ho-Jae, Kang, Ju-Won, Park, Kwon-Moo 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 8 257-268 (12 pages)

Han, Ho-Jae, Kang, Ju-Won, Park, Kwon-Moo 저
...
- 4,100원
Diabetes mellitus is associated with a wide range of pathophysiologic changes in the kidney. This study was designed to examine the mechanisms by which glucose modulates the expression of polarized membrane transport functions in primary cultured rabbit renal proximal tubule cells. Results are as follows: The rate of 30 minute Rb+ uptake was significantly higher(137.76±5.40%) in primary renal tubular cell cultures treated with 20 mM glucose than that of 5 mM glucose. Not the level of mRNA for...
242.

Effect of Probenecid on Tetraethylammonium (TEA) Transport Across Basolateral Membrane of Rabbit Proximal Tubule

Choi, Tae-Ryong, Kim, Yong-Keun, 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 7 249-256 (8 pages)

Choi, Tae-Ryong, Kim, Yong-Keun, 저
...
- 3,000원
The effect of probenecid on the transport of tetraethylammonium (TEA) was studied in renal cortical slices and isolated membrane vesicles to investigate the interaction of organic anion with the organic cation transport system in proximal tubule. Probenecid reversibly inhibited TEA uptake by renal cortical slices in a dose-dependent manner over the concentration range of 1 and 5 mM. The efflux of TEA was not affected by the presence of 3 mM probenecid. Kinetic analysis indicated that probenecid...
243.

Effect of Two Hours Head-down Bedrest on Orthostatic Tolerance

Park, Won-Kyun, Lyo, Woon-Jae, Bae, Jae-Hoon, Song, Dae-Kyu, Chae, E-Up 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 6 237-248 (12 pages)

Park, Won-Kyun, Lyo, Woon-Jae, Bae, Jae-Hoon, Song, Dae-Kyu, Chae, E-Up 저
...
- 4,100원
This study was carried out to determine the effect of -6˚ head-down bedrest on the cardiovascular and hormonal responses to orthostasis and to evaluate the mechanism of orthostatic intolerance. Ten healthy young men were changed the body position from -6˚ head-down or supine bedrest for 2 hr to 70˚ head-up tilt for 20 min. During the bedrest, there were no differences in hemodynamic and hormonal changes between the head-down and the supine positions. However, the tendency of decreased...
244.

Isolation and Characterization of Endosome Subpopulation in Chinese Hamster Ovarian Cells

Suh, Duk-Joon, Park, Mi-Yeon, Jung, Dong-Keun, Bae, Hae-Rahn 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 2 197-208 (12 pages)

Suh, Duk-Joon, Park, Mi-Yeon, Jung, Dong-Keun, Bae, Hae-Rahn 저
...
- 4,100원
Endosomes lower their internal pH by an ATP-driven proton pump, which is critical to dissociation of many receptor-ligand complexes, the first step in the intracellular sorting of internalized receptors and ligands. Endosomes are known to exhibit n great range of pH values that can vary between 5.0 and 7.0 within a single cell although the factors that regulate endosomal pH remain uncertain. To evaluate the morphological and topological differences of endosomes in the different stages, confocal...
245.

Effects of Insulin and IGFs on Phosphate Uptake in Primary Cultured Rabbit Renal Proximal Tubule Cells

Han, Ho-Jae, Park, Kwon-Moo 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 7 63-76 (14 pages)

Han, Ho-Jae, Park, Kwon-Moo 저
...
- 4,300원
The aim of present study was to characterize phosphate uptake and to investigate the mechanism for the insulin and insulin-like growth factor(IGF) stimulation of phosphate uptake in primary cultured rabbit renal proximal tubule cells. Results were as follows : 1. The primary cultured proximal tubule cells had accumulated 6.68±0.70 nmole phosphate/mg protein in the presence of 140 mM NaCl and 2.07±0.17 nmole phosphate/mg protein in the presence of 140 mM KCl during a 60 minute uptake period....
246.

Contractile and Electrical Responses of Guinea-pig Gastric Smooth Muscle to Bradykinin

Kim, Chul-Soo, Jun, Jae-Yeoul, Kim, Sung-Joon, So, In-Suk, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 5 233-242 (10 pages)

Kim, Chul-Soo, Jun, Jae-Yeoul, Kim, Sung-Joon, So, In-Suk, Kim, Ki-Whan 저
...
- 3,000원
The nonapeptide bradykinin has been shown to exhibit an array of biological activities including relaxation/contraction of various smooth muscles. In order to investigate the effects of bradykinin on the contractility and the electrical activity of antral circular muscle of guinea-pig stomach, the isometric contraction and membrane potential were recorded. Also, using standard patch clamp technique, the Ca2+-activated K currents were recorded to observe the change in cytosolic Ca2+...
247.

Effects of In Vitro Exposure to Silica on Bioactive Mediator Release by Alveolar Macrophages

Lee, Ji-Hee 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 1 1-12 (12 pages)

Lee, Ji-Hee 저
...
- 4,100원
Alveolar macrophages play a pivotal role in the pathogenesis of silicosis since the macrophages may release a wide variety of toxic and inflammatory mediators as well as mitogenic growth factors. In the present study, the effects of in vitro exposure to silica on release of various mediator such as reactive oxygen species, platelet activating factor(PAF), and interleukin-1 (IL-1) by alveolar macrophages were examined. First, hydrogen peroxide release from alveolar macrophages was monitored by...
248.

Effects of Lemakalim, a Potassium Channel Opener, on the Contractility and Electrical Activity of the Antral Circular Muscle in Guinea-Pig Stomach

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 4 37-50 (14 pages)

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 저
...
- 4,300원
Synthetic potassium channel openers (KCOs) are agents capable of opening K-channels in excitable cells. These agents are known to have their maximal potency in the smooth muscle tissue, especially in the vascular smooth muscle. Much attention has been focused on the type of K-channel that is responsible for mediating the effects of KCOs. As the KCO-induced changes are antagonized by glibenclamide, an KATP (ATP-sensitive K-channel) blocker in the pancreatic β-cell, KATP was suggested to be the...
249.

Ventilatory Responses to Continuous Negative Pressure Breathing(CNPB) in Awake Dogs

Cha, Eun-Jong, Goo, Yong-Sook 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 1호 4 37-50 (14 pages)

Cha, Eun-Jong, Goo, Yong-Sook 저
...
- 4,300원
Ventilatory responses to inhaled CO2 were measured during continuous negative pressure breathing (CNPB) in awake dogs. End expiratory lung volume (EELV) decreased linearly with pressure level during CNPB (correlation coefficient= 0.81, p<0.005) during air breathing. When CNPB was applied during 5% CO2 inhalation, the decrease in EELV was not significantly different (p<0.5) from that during air breathing. As a result of a lowered EELV, tidal volume (VT) significantly decreased by 22% and...
250.

Reflex Action of the Semicircular Canals on Cervical Extensor and Flexor Muscles in Cats

Kim, Jeh-Hyub, Park, Jong-Seong, 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 2호 7 151-158 (8 pages)

Kim, Jeh-Hyub, Park, Jong-Seong, 저
...
- 3,000원
In urethane anesthetized cats, each vestibular semicircular canal nerve was electrically stimulated, and reflex responses of the cervical extensor and flexor (the splenius capitis and sternomastoid muscles) were recorded by means of electromyography. Stimulation of a unilateral (anterior, horizontal or posterior) canal nerve elicited excitation of the contralateral cervical muscles and inhibition of the ipsilateral ones; during the canal nerve stimulation, the two muscles in one side of the neck...

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