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261.

Effect of Berberine on Depression- and Anxiety-Like Behaviors and Activation of the Noradrenergic System Induced by Development of Morphine Dependence in Rats

BombiLee, BongjunSur, MijungYeom, InsopShim, HyejungLee, Dae-HyunHahm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.6 2 379-386 (8 pages)

BombiLee, BongjunSur, MijungYeom, InsopShim, HyejungLee, Dae-HyunHahm 저
...
- 3,000원
in the forced swimming test and increased open-arm exploration in the elevated plus maze test. BER administration also significantly blocked the increase in hypothalamic CRF expression and TH expression in the locus coeruleus (LC) and the decrease in hippocampal brain-derived neurotrophic factor (BDNF) mRNA expression. Taken together, these findings demonstrated that BER administration significantly reduced morphine withdrawal-associated behaviors following discontinuation of repeated morphine...
262.

The Protective Effect of Eupatilin against Hydrogen Peroxide-Induced Injury Involving 5-Lipoxygenase in Feline Esophageal Epithelial Cells

JaeChunLim, SunYoungPark, YoonjinNam, ThanhThaoNguyen, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.5 4 313-320 (8 pages)

JaeChunLim, SunYoungPark, YoonjinNam, ThanhThaoNguyen, UyDongSohn 저
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- 3,000원
In this study, we focused to identify whether eupatilin (5,7-dihydroxy-3',4',6-trimethoxyflavone), an extract from Artemisia argyi folium, prevents H2O2-induced injury of cultured feline esophageal epithelial cells. Cell viability was measured by the conventional MTT reduction assay. Western blot analysis was performed to investigate the expression of 5-lipoxygenase by H2O2 treatment in the absence and presence of inhibitors. When cells were exposed to 600 ՌM H2O2 for 24 hours, cell...
263.

Effects of Treadmill Exercise on the Recovery of Dopaminergic Neuron Loss and Muscle Atrophy in the 6-OHDA Lesioned Parkinson's Disease Rat Model

Myoung-AeChoe, Byung-SooKoo, GyeongJuAn, SongheeJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.5 3 305-312 (8 pages)

Myoung-AeChoe, Byung-SooKoo, GyeongJuAn, SongheeJeon 저
...
- 3,000원
This study was to determine the effect of exercise on the recovery of dopaminergic neuron loss and muscle atrophy in 6-OHDA-induced hemi Parkinson's disease model. Exercise was loaded twice per day for 30 minutes each time, at 5 days after 6-OHDA lesioning and continued for 16 days using a treadmill. Exercise significantly increased the number of tyrosine hydroxylase positive neuron in the lesioned substantia nigra and the expression level of tyrosine hydroxylase in the striatum compared with...
264.

Effects of Single Treatment of Anti-Dementia Drugs on Sleep-Wake Patterns in Rats

Ji-YoungJung, MootaekRoh, Kyung-KyunKo, Hwan-SooJang, , Seong-RyongLee, Jeoung-HeeHa, Il-SungJang, , Ho-WonLee, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.4 2 231-236 (6 pages)

Ji-YoungJung, MootaekRoh, Kyung-KyunKo, Hwan-SooJang, , Seong-RyongLee, Jeoung-HeeHa, Il-SungJang, , Ho-WonLee, Maan-GeeLee 저
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- 3,000원
We studied the effects of acetylcholinesterase inhibitors, donepezil and galantamine, and an N-methyl-D-aspartate (NMDA) receptor blocker, memantine, on sleep-wake architecture in rats. Screw electrodes were chronically implanted into the frontal and parietal cortex for the electroencephalography (EEG). EEG was recorded with a bio-potential amplifier for 8 h from 09:30 to 17:30. Vibration was recorded to monitor animal activity with a vibration measuring device. Sleep-wake states such as wake...
265.

Tat-Mediated p66shc Transduction Decreased Phosphorylation of Endothelial Nitric Oxide Synthase in Endothelial Cells

SangKiLee, JiYoungLee, HeeKyoungJoo, EunJungCho, CukSeongKim, SangDoLee, JinBongPark, ByeongHwaJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 8 199-204 (6 pages)

SangKiLee, JiYoungLee, HeeKyoungJoo, EunJungCho, CukSeongKim, SangDoLee, JinBongPark, ByeongHwaJeon 저
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- 3,000원
We evaluated the role of Tat-mediated p66shc transduction on the activation of endothelial nitric oxide synthase in cultured mouse endothelial cells. To construct the Tat-p66shc fusion protein, human full length p66shc cDNA was fused with the Tat-protein transduction domain. Transduction of TAT-p66shc showed a concentration- and time-dependent manner in endothelial cells. Tat-mediated p66shc transduction showed increased hydrogen peroxide and superoxide production, compared with Tat-p66shc...
266.

Generation of CD2＋CD8＋ NK Cells from c-Kit＋ Bone Marrow Cells in Porcine

KyuHeeLim, Ji-HuiHan, YoonSeokRoh, BumseokKim, Jung-KeeKwon, MyoungJoYou, HoJaeHan, SohailEjaz6, Chang-WonKang, Jong-HoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 3 167-174 (8 pages)

KyuHeeLim, Ji-HuiHan, YoonSeokRoh, BumseokKim, Jung-KeeKwon, MyoungJoYou, HoJaeHan, SohailEjaz6, Chang-WonKang, Jong-HoonKim 저
...
- 3,000원
Natural killer (NK) cells provide one of the initial barriers of cellular host defense against pathogens, in particular intracellular pathogens. Because bone marrow-derived hematopoietic stem cells (HSCs), lymphoid protenitors, can give rise to NK cells, NK ontogeny has been considered to be exclusively lymphoid. Here, we show that porcine c-kit＋ bone marrow cells (c-kit＋ BM cells) develop into NK cells in vitro in the presence of various cytokines [interleukin (IL)-2, IL-7, IL-15, IL-21, stem...
267.

Cilostazol Decreases Ethanol-Mediated TNFalpha Expression in RAW264.7 Murine Macrophage and in Liver from Binge Drinking Mice

YounJuLee, JongRyeolEun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 8 131-138 (8 pages)

YounJuLee, JongRyeolEun 저
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- 3,000원
Alcoholic hepatitis is a leading cause of liver failure in which the increased production of tumor necrosis factor Ձ (TNFՁ) plays a critical role in progression of alcoholic liver disease. In the present study, we investigated the effects of cilostazol, a selective inhibitor of type III phosphodiesterase on ethanol-mediated TNFՁ production in vitro and in vivo, and the effect of cilostazol was compared with that of pentoxifylline, which is currently used in clinical trial....
268.

Bile Acid Inhibition of N-type Calcium Channel Currents from Sympathetic Ganglion Neurons

HyeKyungLee, KyoungHwaLee, Eui-SicCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 4 25-30 (6 pages)

HyeKyungLee, KyoungHwaLee, Eui-SicCho 저
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- 3,000원
Under some pathological conditions as bile flow obstruction or liver diseases with the enterohepatic circulation being disrupted, regurgitation of bile acids into the systemic circulation occurs and the plasma level of bile acids increases. Bile acids in circulation may affect the nervous system. We examined this possibility by studying the effects of bile acids on gating of neuronal (N)-type Ca2＋ channel that is essential for neurotransmitter release at synapses of the peripheral and central...
269.

Role of Regulators of G-Protein Signaling 4 in Ca2＋ Signaling in Mouse Pancreatic Acinar Cells

SoonhongPark, Syng-IllLee, DongMinShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 9 383-388 (6 pages)

SoonhongPark, Syng-IllLee, DongMinShin 저
...
- 3,000원
Regulators of G-protein signaling (RGS) proteins are regulators of Ca2＋ signaling that accelerate the GTPase activity of the G-protein Ձ-subunit. RGS1, RGS2, RGS4, and RGS16 are expressed in the pancreas, and RGS2 regulates G-protein coupled receptor (GPCR)-induced Ca2＋ oscillations. However, the role of RGS4 in Ca2＋ signaling in pancreatic acinar cells is unknown. In this study, we investigated the mechanism of GPCR-induced Ca2＋ signaling in pancreatic acinar cells derived from...
270.

The Neuroprotective Potential of Cyanidin-3-glucoside Fraction Extracted from Mulberry Following Oxygen-glucose Deprivation

MohammadIqbalHossainBhuiyan, Hyun-BokKim, SeongYunKim, Kyung-OkCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 6 353-362 (10 pages)

MohammadIqbalHossainBhuiyan, Hyun-BokKim, SeongYunKim, Kyung-OkCho 저
...
- 3,000원
In this study, cyanidin-3-glucoside (C3G) fraction extracted from the mulberry fruit (Morus alba L.) was investigated for its neuroprotective effects against oxygen-glucose deprivation (OGD) and glutamate-induced cell death in rat primary cortical neurons. Cell membrane damage and mitochondrial function were assessed by LDH release and MTT reduction assays, respectively. A time-course study of OGD-induced cell death of primary cortical neurons at 7 days in vitro (DIV) indicated that neuronal...

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