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21.

A Simple Dosing Scheme for Intravenous Busulfan Based on Retrospective Population Pharmacokinetic Analysis in Korean Patients

SangminChoe, GayeongKim, Hyeong-SeokLim, Sang-HeonCho, Jong-LyulGhim, JinAhJung, Un-JibKim, GyujeongNoh, Kyun-SeopBae, DonghoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.4 7 273-280 (8 pages)

SangminChoe, GayeongKim, Hyeong-SeokLim, Sang-HeonCho, Jong-LyulGhim, JinAhJung, Un-JibKim, GyujeongNoh, Kyun-SeopBae, DonghoLee 저
...
- 3,000원
Busulfan is an antineoplastic agent with a narrow therapeutic window. A post-hoc population pharmacokinetic analysis of a prospective randomized trial for comparison of four-times daily versus once-daily intravenous busulfan was carried out to search for predictive factors of intravenous busulfan (iBu) pharmacokinetics (PK). In this study the population PK of iBu was characterized to provide suitable dosing recommendations. Patients were randomized to receive iBu, either as 0.8 mg/kg every 6 h...
22.

Cytotoxicities and Quantitative Structure Activity Relationships of B13 Sulfonamides in HT-29 and A549 Cells

SeulKiChanLee, SangMinPark, ChaeukIm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 14 423-430 (8 pages)

SeulKiChanLee, SangMinPark, ChaeukIm 저
...
- 3,000원
field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were used to carry out QSAR molecular modeling of these compounds. The predictive CoMSIA models for HT-29 and A549 gave cross-validated q2 values of 0.703 and 0.830, respectively. From graphical analysis of these models, we suppose that the stereochemistry of 1,3-propandiol is not important for activity and that introduction of a sulfonamide group and long alkyl chains into B13 can increase cytotoxicity.
23.

Role of Regulators of G-Protein Signaling 4 in Ca2＋ Signaling in Mouse Pancreatic Acinar Cells

SoonhongPark, Syng-IllLee, DongMinShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 9 383-388 (6 pages)

SoonhongPark, Syng-IllLee, DongMinShin 저
...
- 3,000원
Regulators of G-protein signaling (RGS) proteins are regulators of Ca2＋ signaling that accelerate the GTPase activity of the G-protein Ձ-subunit. RGS1, RGS2, RGS4, and RGS16 are expressed in the pancreas, and RGS2 regulates G-protein coupled receptor (GPCR)-induced Ca2＋ oscillations. However, the role of RGS4 in Ca2＋ signaling in pancreatic acinar cells is unknown. In this study, we investigated the mechanism of GPCR-induced Ca2＋ signaling in pancreatic acinar cells derived from...
24.

Assessment of Flavin-containing Monooxygenase (FMO) Activity by Determining Urinary Ratio of Theobromine and Caffeine in a Korean Population after Drinking a Cup of Coffee

Woon-GyeChung, , Ju-HeeKang, Hyung-KeunRoh, Kyung-HoonLee, Chang-ShinPark, Young-NamCha, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 11 207-213 (7 pages)

Woon-GyeChung, , Ju-HeeKang, Hyung-KeunRoh, Kyung-HoonLee, Chang-ShinPark, Young-NamCha, 저
...
- 3,000원
To examine individual variation in drug metabolism catalyzed by flavin-containing monooxygenase (FMO), 179 Korean volunteers' urinary molar concentration ratio of theobromine (TB) and caffeine (CA) was determined. Their urine was collected for 1 hr (between 4 and 5 hrs) after they drank a cup of coffee containing 115 mg CA and analyzed by an HPLC system. The lowest TB/CA ratio obtained was 0.40, the highest ratio was 15.17 (38-fold difference), and the median ratio for all subjects was 1.87....
25.

Psychiatric Education in U.S. Medical Schools

Wun Jung Kim 대한신경정신의학회 신경정신의학 10 Pages

대한신경정신의학회 신경정신의학 1993, 제 32권 제 5호 1 611-620 (10 pages)

Wun Jung Kim 저
...
- 3,000원
미국의과대학 교육 경향이 최근 10여년간 많이 변화하고 있고 정신의학교육도 일반의학교육추세에 맞게 변하고 있다. 강의 • 주입식 교습 방법이 소집단 토론, 자율학습, 문제점 위주의 학습(Problem Based Learning), 임상실습중심의 교육으로 바뀌어 지고 있다. 기초의학으로서의 행동과학 및 정 신과학 교육도 임상적 요소를 많이 가미하며 또한 임상실습기간중에도 기초의학을 교습하는 둥 종래의 괴리현상이 줄어들고 있으며 각 과간의, 또한 기초의학, 임상의학간의 유기적，종합적 교육을 지향하고 있다. 저자는 이 논문에서...
26.

정신분열병 환자에서의 산과적 합병증 및 신체기형

신철진, 김용식 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 1994, 제 33권 제 5호 11 1054-1062 (9 pages)

신철진, 김용식 저
...
- 3,000원
27.

精神科入院患者의 自殺에 對한 몇 가지 臨床的考察

李相換, 趙斗英 대한신경정신의학회 신경정신의학 7 Pages

대한신경정신의학회 신경정신의학 1981, 제 20권 제 1호 4 36-42 (7 pages)

李相換, 趙斗英 저
...
- 3,000원
28.

Ion Channels for Communication Between and Within Cells -Annual Review Lecture, October 16th, 1992-

Neher, Erwin 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 1호 1 1-12 (12 pages)

Neher, Erwin 저
...
- 4,100원
29.

적출된 토끼와 자라심장에서의 Ca++ Pool

김인교(Kim, In-Kyo), 이중우(Lee, Joong-Woo), 강두희(Kang, Doo-Hee) 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1975, 제 9권 제 1호 2 13-22 (10 pages)

김인교(Kim, In-Kyo), 이중우(Lee, Joong-Woo), 강두희(Kang, Doo-Hee) 저
...
- 3,000원
30.

Inhibitory Effect of Chitosan and Phosphate Cross-linked Chitosan against Cucumber Mosaic Virus and Pepper Mild Mottle Virus

Venkata Subba Reddy Gangireddygari, Bong Nam Chung, In-Sook Cho, Ju-Yeon Yoon 한국식물병리학회 The Plant Pathology Journal 9 Pages

한국식물병리학회 The Plant Pathology Journal 2021, 37권 6호 12 632-640 (9 pages)

Venkata Subba Reddy Gangireddygari, Bong Nam Chung, In-Sook Cho, Ju-Yeon Yoon 저
...
- 3,000원
Cucumber mosaic virus (CMV) and Pepper mild mot- tle virus (PMMoV) causes severe economic loss in crop productivity of both agriculture and horticulture crops in Korea. The previous surveys showed that naturally available biopolymer material – chitosan (CS), which is from shrimp cells, reduced CMV accumulation on pepper. To improve the antiviral activity of CS, it was synthesized to form phosphate cross-linked chitosan (PCS) and compared with the original CS. Initially, the activity of CS...

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