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Influence of rutin on the effects of neonatal cigarette smoke exposure-induced exacerbated MMP-9 expression, Th17 cytokines and NF-kB/iNOS-mediated inflammatory responses in asthmatic mice model
Li-Li Liu, Yan Zhang, Xiao-Fang Zhang, Fu-Hai Li 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 2 481-491 (11 pages)
Allergic asthma is one of the most enduring diseases of the airway. The Thelper cells and regulatory T-cells are critically involved in inflammatory responses, mucus hypersecretion, airway remodelling and in airway hyper-responsiveness. Cigarette smoke (CS) has been found to aggravate inflammatory responses in asthma. Though currently employed drugs are effective, associated side effects demand identification and development of novel drugs with negligible or no adverse effects. Rutin,... -
Metabotropic glutamate receptor dependent long-term depression in the cortex
SukjaeJoshuaKang, Bong-KiunKaang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.6 1 557-564 (8 pages)
Metabotropic glutamate receptor (mGluR)-dependent long-term depression (LTD), a type of synaptic plasticity, is characterized by a reduction in the synaptic response, mainly at the excitatory synapses of the neurons. The hippocampus and the cerebellum have been the most extensively studied regions in mGluR-dependent LTD, and Group 1 mGluR has been reported to be mainly involved in this synaptic LTD at excitatory synapses. However, mGluR-dependent LTD in other brain regions may be involved in the... -
Long-term Synaptic Plasticity: Circuit Perturbation and Stabilization
JooMinPark, Sung-CherlJung, Su-YongEun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 2 457-460 (4 pages)
At central synapses, activity-dependent synaptic plasticity has a crucial role in information pro-cessing, storage, learning, and memory under both physiological and pathological conditions. One widely accepted model of learning mechanism and information processing in the brain is Hebbian Plasticity: long-term potentiation (LTP) and long-term depression (LTD). LTP and LTD are respectively activity-dependent enhancement and reduction in the efficacy of the synapses, which are rapid and... -
Aortic Remodelling in Chronic Nicotine-Administered Rat
SatirahZainalabidin, SitiBalkisBudin, AnRamalingam, YiChengLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 9 411-418 (8 pages)
Vascular remodelling is an adaptive mechanism, which counteracts pressure changes in blood circulation. Nicotine content in cigarette increases the risk of hypertension. The exact relationship between nicotine and vascular remodelling still remain unknown. Current study was aimed to determine the effect of clinically relevant dosage of nicotine (equivalent to light smoker) on aortic reactivity, oxidative stress markers and histomorphological changes. Twelve age-matched male Sprague-Dawley rats... -
The Development of Phasic and Tonic Inhibition in the Rat Visual Cortex
Hyun-JongJang, Kwang-HyunCho, , Sung-WonPark, Myung-JunKim, ShinHeeYoon, Duck-JooRhie 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.6 8 399-406 (8 pages)
Gamma-aminobutyric acid (GABA)-ergic inhibition is important in the function of the visual cortex. In a previous study, we reported a developmental increase in GABAA receptor-mediated inhibition in the rat visual cortex from 3 to 5 weeks of age. Because this developmental increase is crucial to the regulation of the induction of long-term synaptic plasticity, in the present study we investigated in detail the postnatal development of phasic and tonic inhibition. The amplitude of phasic... -
Hyperosmotic Stimulus Down-regulates 1α, 25-dihydroxyvitamin D3- induced Osteoclastogenesis by Suppressing the RANKL Expression in a Co-culture System
YuShunTian, HyunJooJeong, Sang-DoLee, SeokHeuiKong, Seung-HoOhk, Yun-JungYoo, Jeong-TaegSeo, DongMinShin, Byung-WhaSohn, Syng-IllLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 9 169-176 (8 pages)
The hyperosmotic stimulus is regarded as a mechanical factor for bone remodeling. However, whether the hyperosmotic stimulus affects 1Ձ, 25-dihydroxyvitamin D3 (1Ձ,25(OH)2D3)-induced osteoclastogenesis is not clear. In the present study, the effect of the hyperosmotic stimulus on 1Ձ,25(OH)2D3- induced osteoclastogenesis was investigated in an osteoblast-preosteoclast co-culture system. Serial doses of sucrose were applied as a mechanical force. These hyperosmotic stimuli... -
스코폴라민 첩포가 젊은 정상 성인 남자의 수면 구조에 미치는 영향
김의중, 정도언 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 1995, 제 34권 제 5호 26 1500-1511 (12 pages)
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말초혈관(襪梢血管) 확장제(擴張劑) Ethaverine HCl의 임상효과(臨床效果)의 재평가(再評價)
김윤영(Yoon-Young Kim), 조영원(Young-Won Cho) 대한약리학회 대한약리학잡지 6 Pages
대한약리학회 대한약리학잡지 1975, 제 11권 제 1호 5 33-38 (6 pages)
말정혈관확장제(末精血管擴張劑)인 Ethaverine의 임상효과(임상(臨床效果)는 말초동맥질환(末梢動脈疾患)을 갖인 29명(名)의 당뇨질환자(糖尿疾患者)를 대상으로 이중맹검(二重盲檢) 비교차(非交叉) 방법(方法)에 의(依)하여 연구검토(硏究檢討)하였다. 임상적(臨床的)인 개선(改善)은 간헐성파행증(間歇性跛行症)의 발생빈도(發生頻度)를 포함하는 환노(患老)들의 병역(病歷)으로부터 평가(評價)하였다. Ethaverine을 사주(四週) 치료후(治療後)는 임상증상(臨床症狀)을 개선(改善)하는데 있어 위약(僞藥)에 비(比)하여 효과가 없었다.... -
사회서비스의 사회적 경제 전략
김학실 한국사회서비스학회 사회서비스연구 48 Pages
한국사회서비스학회 사회서비스연구 2017, 제 7권 제 2호 5 127-174 (48 pages)
본 연구는 사회적경제가 사회서비스 제공에 좋은 대안이 될 수 있는지를 모색하고 방안을 제시하기 위한 시론적 연구이다. 우리사회의 사회적경제 역 량이 사회서비스의 공급 주체로써 역할을 수행할 수 있는지를 살펴보았다. 사 회적 경제 조직은 2007년 이후 양적 증가는 이루어졌으나, 현재는 답보상태 이며, 지역별로도 큰 차이를 보이고 있다. 또한 민관협력체제인 중간지원조직 의 역할이 원활하지 않으며, 민주적 운영구조도 미미하다. 사회적경제 역량 분석에 기반하여 사회서비스 제공 영역을 확대하기 위해서는 첫째, 사회적경... -
The Plant-Stress Metabolites, Hexanoic Aacid and Melatonin, Are Potential “Vaccines” for Plant Health Promotion
Anne J. Anderson, Young Cheol Kim 한국식물병리학회 The Plant Pathology Journal 13 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 5호 1 415-427 (13 pages)
A plethora of compounds stimulate protective mecha- nisms in plants against microbial pathogens and abiotic stresses. Some defense activators are synthetic com- pounds and trigger responses only in certain protective pathways, such as activation of defenses under regula- tion by the plant regulator, salicylic acid (SA). This review discusses the potential of naturally occurring plant metabolites as primers for defense responses in the plant. The production of the metabolites, hexanoic acid and...


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