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Are Spinal GABAergic Elements Related to the Manifestation of Neuropathic Pain in Rat?
JaeheeLee, SeungKeunBack, EunJeongLim, GyuChongCho, MyungAhKim, HeeJinKim, MinHeeLee, HeungSikNa 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.2 1 59-69 (11 pages)
or neuropathic pain. To these aims, we first analyzed the pain behaviors following the spinal administration of GABA antagonists (1Ռg bicuculline/rat and 5Ռg phaclofen/rat), agonists (1Ռg muscimol/rat and 0.5Ռg baclofen/rat) or GABA transporter (GAT) inhibitors (20Ռg NNC-711/rat and 1Ռg SNAP-5114/rat) into naïve or neuropathic animals. Then, using Western blotting, PCR or immunohistochemistry, we compared the quantities of spinal GABA, its synthesizing... -
Preventing Extracellular Diffusion of Trigeminal Nitric Oxide Enhances Formalin-induced Orofacial Pain
Hwi-SeokJung, Hong-BinJeon, Ik-SungJeon, Bum-JunLee, Hyun-WooYoo, Dong-KukAhn, Dong-HoYoun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.5 8 379-383 (5 pages)
However, the central role of NO in the trigeminal nucleus remains uncertain in support of processing the orofacial nociception. Thus, we here investigated the central role of NO in formalin (3%)-induced orofacial pain in rats by administering membrane-permeable or -impermeable inhibitors, relating to the NO signaling pathways, into intracisternal space. The intracisternal pretreatments with the NO synthase inhibitor L-NAME, the NO-sensitive guanylate cyclase inhibitor ODQ, and the protein kinase... -
Effects of NOS Inhibitors on Arthritis and Arthritic Pain in Rats
SunSeekMin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.6 4 253-258 (6 pages)
of rats with L-N6-(1-iminoethyl)-lysine (L-NIL, 500Ռg, in 50Ռl), an inhibitor of inducible NOS (iNOS), partially prevented the induction of pain-related behavior and partially reduced inflammatory response in the synovial membrane in the knee joint. These results suggest that iNOS in the knee joint may play an important role in the induction of pain-related behavior and inflammation, and that NO produced by iNOS may be associated with nociceptive signaling in the peripheral site. -
Intra-articular Injection of IL-1β Facilitated Formalin-induced Temporomandibular Joint Pain in Freely Moving Rats
HyoSoonChoi, SungChulJung, ByungJuChoi, DongKukAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 4 23-28 (6 pages)
on the formalin-induced temporomandibular joint (TMJ) pain. Under anesthesia, a 30-gauge needle was introduced into the right TMJ region for injection of formalin. Microinjection of 50 μl of 5% formalin significantly produced noxious scratching behavioral response, and the scratching behavior lasted for 40 min. Although the responses produced by formalin injection were divided into two phases, the response of 1st phase did not significantly differ from the scratching behavior response in the... -
韓凰人의 自家痛症評價에 관한 예비적 조사 一 Zung s Self-Rating Pain and Distress Scale에 의한 一
서혜수, 박병탁, 정성덕 대한신경정신의학회 신경정신의학 10 Pages
대한신경정신의학회 신경정신의학 1986, 제 25권 제 4호 9 628-637 (10 pages)
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Effect of Capsaicin on Causalgiform Pain in the Rat
Kim, Kwang-Jin, Jeon, Byeong-Hwa, Kim, Won-Sik, Park, Kyung-Ran, Choi, Sae-Jin 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 2호 6 143-150 (8 pages)
injuries and partial nerve injury is the main cause of causalgiform pain disorders in humans. Here, the left sciatic nerve was ligated unilaterally at the high level of the thigh to prepare an animal model of this pain condition. The rat developed guarding behavior of the ipsilateral hind paw within a few hours after the operation and this behavior was maintained for several months thereafter, suggesting the possibility of spontaneous pain. These animals were divided into two groups(4-week &... -
PLAY IN SESSIONS OF DEVELOPMENTAL TRANSFORMATIONS (DVT) MAY PREVENT HARMFUL BEHAVIOR
Fred Landers 한국연극예술치료학회 한국연극예술치료학회 학술대회지 11 Pages
한국연극예술치료학회 한국연극예술치료학회 학술대회지 2012, 제3회 1 1-11 (11 pages)
Psychotherapy, whether it is verbal therapy or drama therapy, has an effective, well-researched method for helping victims of violence recover from frozen memories of the traumatic experiences that they have suffered (Joseph & Gray, 2008). During a treatment session, a client can reduce the effects of trauma by adjusting the imagery that triggers traumatic memories. The client is receiving good therapy when there is enough exposure to the trauma that the client can express what he or she feels,... -
Effect of Environmental Factors on Depressive-like Behavior and Memory Function in Adolescent Rats
Song Min Kyung, Lee Jae-Min, Kim Yoon Ju, Lee Joo Hee, Kim Youn-Jung 한국기초간호학회 Journal of Korean Biological Nursing Science 8 Pages
한국기초간호학회 Journal of Korean Biological Nursing Science 2017, Volume 19, No 4 7 276-283 (8 pages)
Purpose: The aim of this study was to identify the effects of environmental factors on depressive-like behavior and memory function during adolescence. We performed behavior tests in adolescent rats exposed to environmental enrichment, handling, and social deprivation for eight weeks. Methods: Wistar rats were randomly assigned to control, environmental enrichment, handling, and social deprivation groups at the age of four weeks. Results: In the forced swim test, the immobility time in the... -
PLAY IN SESSIONS OF DEVELOPMENTAL TRANSFORMATIONS(DvT) MAY PREVENT HARMFUL BEHAVIOR
Fred Landers 한국연극예술치료학회 연극예술치료연구 14 Pages
한국연극예술치료학회 연극예술치료연구 2013, 제 3호 1 5-18 (14 pages)
Psychotherapy, whether it is verbal therapy or drama therapy, has an effective, well-researched method for helping victims of violence recover from frozen memories of the traumatic experiences that they have suffered (Joseph & Gray, 2008). During a treatment session, a client can reduce the effects of trauma by adjusting the imagery that triggers traumatic memories. The client is receiving good therapy when there is enough exposure to the trauma that the client can express what he or she feels,...


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