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Identification of differentially expressed genes in gauze-exposed omentum of dogs using differential display RT-PCR
Md. Mizanur Rahman, Yongsun Kim, Ye-Eun Byeon, Hak-Hyun Ryu, Wan Hee Kim, Mahmuda Umme Rayhan, Oh-Kyeong Kweon* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 2호 8 167-173 (7 pages)
Molecular mechanisms governing peritonitis caused by the presence of aseptic gauze have remained unclear. To identify the genes involved, sterile gauze-exposed omentum was collected at 0, 6, 12, 24, and 48 h intervals, and analyzed by differential display RT(reverse transcription)-PCR. Among over 1,200 bands, 230 bands were found differentially expressed. These bands represented the fragment sizes of approximately 200 to 1,500 bp. The eight fragments were expressed differentially in the... -
Development of monoclonal antibodies against the abnormal prion protein isoform (PrP) associated with chronic wasting disease (CWD)
Hyun-Jeong Jeong, Nak-Hyung Lee, Joong-Bok Lee, Seung-Yong Park, Chang-Seon Song, Kun-Ho Seo, Dong-Woon Kim, Yong-Sun Kim, In-So 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 4호 14 429-432 (4 pages)
Monoclonal antibodies (mAbs) specific for the abnormal prion protein isoform (PrP) are indispensable for diagnosing chronic wasting disease (CWD). In this study, eight mAbs were developed by immunizing PrP knockout mice with recombinant elk PrP and an immunogenic PrP peptide. The reactivity of the mAbs to recombinant PrP and the PrP peptide was measured, and their isotypes were subsequently determined. Among them, four mAbs (B85-05, B85-08, B85-12, and B77-75) were shown by Western blotting to... -
Serosurveillance for Japanese encephalitis, Akabane, and Aino viruses for Thoroughbred horses in Korea
Dong-Kun Yang*, Byoung-han Kim, Chang-Hee Kweon, Jin-Ju Nah, Hyun-Joo Kim, Kyung-Woo Lee, Young-Jin Yang, Kyu-Whan Mun 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 4호 7 381-386 (6 pages)
Recent global warming trends may have a significant impact on vector-borne viral diseases, possibly affecting vector population dynamics and disease transmission. This study measured levels of hemagglutination-inhibition (HI) antibodies against Japanese encephalitis virus (JEV) and neutralizing antibodies against Akabane virus (AKAV) and Aino virus (AINV) for Thoroughbred horses in Korea. Blood samples were collected from 989 racehorses in several provinces, between October 2005 and March 2007.... -
Biological characteristics of Chinese hamster ovary cells transfected with bovine Prnp
Sang-Gyun Kang, Deog-Yong Lee, Mi Lan Kang, Han Sang Yoo 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 2호 5 131-137 (7 pages)
A normal prion protein (PrPc) is converted to a proteaseresistant isoform by an apparent self-propagating activity in transmissible spongiform encephalopathy, a neurodegenerative disease. The cDNA encoding open reading frame (ORF) of the bovine prion protein gene (Prnp) was cloned from Korean cattle by PCR, and was transfected into Chinese hamster ovary (CHO-K1) cells using lipofectamine. The gene expression of the cloned cDNA was confirmed by RT-PCR and Western blotting with the monoclonal... -
Cardiac Damage Biomarkers Following a Triathlon in Elite and Non-elite Triathletes
Chan-HoPark, Kwi-BaekKim, JinHan, Jin-GooJi, Yi-SubKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 10 419-423 (5 pages)
after a triathlon race in elite and non-elite athlete groups. Fifteen healthy men participated in the study. Based on performance, they were divided into elite athlete group (EG: n=7) and non-elite athlete group (NEG: n=8). Participants’ blood samples were obtained during four periods: before, immediately, 2 hours and 7 days after finishing the race. creatine kinase (CK), creatine kinase-myoglobin (CK-MB), myoglobin, and lactate dehydrogenase (LDH) were significantly increased in both groups... -
Comparison of Interleukin-8 Levels in Long-Distance Runners and Healthy Sedentary Non-Athletic Control Subjects
Young-OhShin, Jun-SangBae, Ji-WonMin, Jeong-BeomLee, Jung-KyuKim, Young-JuSong, Hun-MoYang, Young-KiMin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.6 6 263-268 (6 pages)
We have previously demonstrated that the level of leukocytes and neutrophils significantly increased immediately and 30 min after exercise. Interleukin-8 (IL-8) is an inflammatory cytokine that acts as a chemokine on neutrophils. In the present study, we evaluated the correlation between the number of neutrophils and leukocytes, and between the number of neutrophils and plasma IL-8 level. Long-distance trained runners (TRs, n = 10) and untrained sedentary control subjects (SEDs, n = 10) ran for... -
정신분열병 환자의 비정형 항정신병약물 반응과 세로토닌 2A 및 도파민 D3 수용체 유전자 다형성의 관련연구
김병수, 주연호, 김창윤, 박지홍, 송규영, 한오수 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 2002, 제 41권 제 3호 4 409-420 (12 pages)
연구목적: 본 연구는 정신분열병 환자군을 대상으로 비정형 항정신병 약물에 대한 반응과 도파민 D3 수용체 유전자 및 세로토닌 2A 수용체 유전자의 관련성을 확인하기 위해 시행되었다. 방 법: 서울중앙병원 정신과에서 치료 받은 환자 중에서 정신장애의 진단 및 통계 편람 제 4 판(DSM-Ⅳ) 의 정신분열병 진단 기준에 부합되는 환자 75명(남자 39명, 여자 36명)을 대상으로 하였다. 모든 대 상 환자들(혹은 보호자)은 본 연구의 목적과 과정에 대한 설명을 들은 후 서면 동의를 하였다. 약물 반응을 평가하기 위해서 CGI(Clinical... -
중·고등학교 청소년의 자살사고 및 자살시도의 유병률과 자살시도의 위험요인에 관한 연구
조성진, 전홍진, 김장규, 서동우, 김선욱, 함봉진, 서동혁, 정선주, 조맹제 대한신경정신의학회 신경정신의학 14 Pages
대한신경정신의학회 신경정신의학 2002, 제 41권 제 6호 18 1142-1155 (14 pages)
연구목적: 지역사회에 거주하고 있는, 중·고등학교 청소년들을 대상으로 자살 사고 및 자살시도의 빈도, 성별 과 연령(13~15세 vs 16~18세)에 따른 자살사고 및 시도의 빈도에 차이가 있는지 여부, 자살사고 및 자살시도가 있는 청소년의 특징, 그리고 자살시도의 위험요인을 알아보고자 하였다. 방 법: 부천시에 소재하고 있는 중학교 24개교 및 고등학교 20개교의 청소년 71,102명중에서 무작위 집 락 표본 추출범으로 청소년 2,203명(남자 1,105명, 여자 1,098명)을 조사대상으로 선정하였다. 자살 시도 및 자살사고의 정의에 관한...


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