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301.

The Protective Effect of Melatonin Administration against Adriamycin-induced Cardiotoxicity in Rats

JinHan, ChungheeKim, NariKim, JuheePark, YoungchurlYang, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.4 6 333-342 (10 pages)

JinHan, ChungheeKim, NariKim, JuheePark, YoungchurlYang, EuiyongKim 저
...
- 3,000원
Adriamycin is a commonly used chemotherapeutic agent for cancer, including acute leukemia, lymphoma, and a number of solid human tumors. However, recent studies have recognized severe cardiotoxicity after an acute dose, which are likely the result of generation of free radicals and lipid peroxidation. Therefore, the clinical uses of adriamycin have been limited. Melatonin, the pineal gland hormone known for its ability to modulate circardian rhythm, has recently been studied in its several...
302.

Thyroid Hormone-Induced Alterations of Ryanodine and Dihydropyridine Receptor Protein Expression in Rat Heart

HaeWonKim, MiyoungPark, EunHeeLee, HyoungJinCho, HeeRanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 11 329-337 (9 pages)

HaeWonKim, MiyoungPark, EunHeeLee, HyoungJinCho, HeeRanLee 저
...
- 3,000원
Thyroid hormone-induced cellular dysfunctions may be associated with changes in the intracellular Ca2⁢ concentration. The ryanodine receptor, a Ca2⁢ release channel of the SR, is responsible for the rapid release of Ca2⁢ that activates cardiac muscle contraction. In the excitation-contaction coupling cascade, activation of ryanodine receptors is initiated by the activity of sarcolemmal Ca2⁢ channels, the dihydropyridine receptors. In hyperthyroidism left ventricular...
303.

Minimal Amount of Insulin Can Reverse Diabetic Heart Function Sarcoplasmic Reticulum Ca2+ Transport and Phospholamban Protein Expression

HaeWonKim, YongSunCho, YunSongLee, EunHeeLee, HeeRanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 7 175-182 (8 pages)

HaeWonKim, YongSunCho, YunSongLee, EunHeeLee, HeeRanLee 저
...
- 3,000원
In the present study, the underlying mechanisms for diabetic functional derangement and insulin effect on diabetic cardiomyopathy were investigated with respect to sarcoplasmic reticulum (SR) Ca2⁢-ATPase and phospholamban at the transcriptional and translational levels. The maximal Ca2⁢ uptake and the affinity of Ca2⁢-ATPase for Ca2⁢ were decreased in streptozotocin-induced diabetic rat cardiac SR, however, even minimal amount of insulin could reverse both parameters....
304.

Angiotensin-Converting Enzyme Gene Polymorphism is not Associated with Myocardial Infarction in Koreans

SeokChaiDong-RyulSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 13 645-650 (6 pages)

SeokChaiDong-RyulSohn 저
...
- 3,000원
typed by polymerase chain reaction. The I allelic frequency of ACE gene in Korean subjects was irrelavant to myocardial infarction (patients, 65%; control subjects 66%), as was true with the D allele. When compared with other populations, the frequency of D allele in Koreans (0.34) was lower than that in Caucasians, and was close to that of other Oriental populations. The data suggest that the ACE gene polymorphism is not an independent genetic risk factor for myocardial infarction in Koreans.
305.

The Effects of Intracellular Monocarboxylates on the ATP-sensitive Potassium Channels in Rabbit Ventricular Myocytes

NariKim, JinHan, Eui-YongKim, Won-KyungHo, YungE.Earm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 6 581-589 (9 pages)

NariKim, JinHan, Eui-YongKim, Won-KyungHo, YungE.Earm 저
...
- 3,000원
A regulating mechanism of the ATP-sensitive potassium channels (KATP channels) is yet to fully explained. This study was carried out to investigate the effects of intracellular application of monocarboxylates (acetate, formate, lactate, and pyruvate) on KATP channels in isolated rabbit ventricular myocytes. Single channel currents of KATP channels were recorded using the excised inside-out or permeabilized attached (open-cell) patch-clamp technique at room temperature. Intracellular application...
306.

Higher Serum C Reactive Protein Determined C Reactive Protein Single-Nucleotide Polymorphisms Are Involved in Inherited Depression

Shiliang Wang, Hua Zhong, Meijuan Lu, Guohua Song, Xiaomei Zhang, Min Lin, Shengliang Yang, Mincai Qian 대한신경정신의학회 Psychiatry Investigation 5 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 12 824-828 (5 pages)

Shiliang Wang, Hua Zhong, Meijuan Lu, Guohua Song, Xiaomei Zhang, Min Lin, Shengliang Yang, Mincai Qian 저
...
- 1,500원
Objective_The pathogenesis of depression is not fully understood yet, but studies have suggested higher circulating C reactive protein (CRP) level might relate to depression occurrence. However, due to high variability of patients’ individual condition, the results to date are inconsistent. Considering CRP single-nucleotide polymorphisms (SNPs) could also regulate plasma CRP levels, in the present study, we hypothesized that inherited CRP allelic variations may co-vary with depressive...
307.

The Staging of Major Mood Disorders

Ather Muneer, Rana Mazommil 대한신경정신의학회 Psychiatry Investigation 12 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 2 747-758 (12 pages)

Ather Muneer, Rana Mazommil 저
...
- 4,100원
Objective_Staging of psychiatric disorders is gaining momentum and the purpose of this review is to examine whether major mood disorders can be defined according to stages. Methods_In April 2018 the PubMed electronic data base was scrutinized by a combination of various search terms like “major depressive disorder and staging,” “bipolar disorder and neuroprogression,” etc. To incorporate the latest findings the search was limited to the last 10 years. Both original and review articles were...
308.

韓國精神障碍의 疫學的調査硏究(ⅩⅧ) - 社會恐怖症과 國家別比較 -

李定均, 李奎恒 대한신경정신의학회 신경정신의학 7 Pages

대한신경정신의학회 신경정신의학 1997, 제 36권 제 3호 17 571-577 (7 pages)

李定均, 李奎恒 저
...
- 3,000원
309.

정신분열병 환자의 우울증에서 Paroxetine과 삼환계 항우울제 병용치료

심주철, 공보금, 박정환, 윤영란, 신재국, 김정익, 안동성, 김용관, 차인준, 김영훈 대한신경정신의학회 신경정신의학 10 Pages

대한신경정신의학회 신경정신의학 1997, 제 36권 제 4호 14 732-741 (10 pages)

심주철, 공보금, 박정환, 윤영란, 신재국, 김정익, 안동성, 김용관, 차인준, 김영훈 저
...
- 3,000원
저자들은 마산동서병원에 입원중인 우울증이 동반된 정신분열증 환자 10명을 대상으로 사용중인 항정신병 약물에 paroxetine과 저용량의 삼환계 항우울제를 6주간 병용투여한 후 우울증상에 대한 효과와 치료의 안 전성 및 약물상호작용을 알아보았다. Paroxetine은 고정량의 항정신병약물과 삼환계 항우울제에 부가하여 일일 20mg을 6주간 병용하게 하였으며, 임상상태는 HDRS, HARS, UKU Side Effect Rating Scale 등의 평가척도를 사용하여 평가하였다. 또한 약동학적 약물상호작용은 삼환계 항우울제들의 혈장농도를 HPLC로 측정하여...
310.

청소년에서 폭력에의 노출과 관련된 정신의학적 증상

이호분, 민성길, 전여숙, 송동호, 육기환, 김동기 대한신경정신의학회 신경정신의학 10 Pages

대한신경정신의학회 신경정신의학 1998, 제 37권 제 2호 6 251-260 (10 pages)

이호분, 민성길, 전여숙, 송동호, 육기환, 김동기 저
...
- 3,000원
서울 시내 중학생 1345명을 대상으로 폭력에 노출되는 정도와 이와 연관된 정신의학적 증상을 알아보고 자 하였다. 이를 위해 자기보고식 설문지를 사용하였는데, 설문지의 내용은 사회인구학적 자료와 집, 학교, 동네에서 폭력을 당하거나 목격했는지를 묻는 문항과 폭력에 의한 정신의학적 증상의 정도를 묻는 TSC(trauma symptom checklist)로 구성되었으며, 그 결과는 다음과 같다. 1) 전체 학생 중 45%가 폭력에 노출된 경험이 있었으며, 남자가 여자보다 많았다(p<0.025). 집에서 구타 당한 경험은 여학생이 22.8%로 남학생보다...

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