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Unique features of bovine lymphocytes exposed to a staphylococcal enterotoxin
Yong Ho Park, Sang Un Lee, Witold A. Ferens, Sparrow Samuels, William C. Davis, Lawrence K. Fox, Jong Sam Ahn, Keun Seok Seo, By 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 3호 5 233-239 (7 pages)
We previously demonstrated that stimulation of bovine peripheral blood mononuclear cells (PBMCs) with staphylococcal enterotoxin C (SEC), led to an inversion of the CD4+:CD8+ T cell ratio and generation of an atypical CD8+ T cell subpopulation expressing CD26. In the present study, we examined T cell apoptosis and proliferation profiles of PBMC subpopulations in cultures stimulated with SEC. Unlike when stimulated with concanavalin A, nucleic acid synthesis in bovine PBMC cultures stimulated... -
Absence of vertical transmission of Helicobacter pylori in an experimental murine model
Jin-Uk Lee, Kwoni Jung, Okjin Kim 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 3호 3 225-228 (4 pages)
Helicobacter pylori (H. pylori) infection is acquired mainly in early childhood but the precise transmission routes are unclear. This study examined the maternal H. pylori infection status in order to determine the potential of perinatal transmission. These issues were investigated using an experimental murine model, the Mongolian gerbil, which has been reported to be the most suitable laboratory animal model for studying H. pylori. Pregnant Mongolian gerbils, infected experimentally with H.... -
Altered expression of thioredoxin reductase-1 in dysplastic bile ducts and cholangiocarcinoma in a hamster model
Byung-IL Yoon, Dae-Yong Kim, Ja-June Jang, Jeong-Hee Han 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 3호 1 211-216 (6 pages)
been implicated in cell proliferation, transformation and anti-apoptosis. In the present study, using a hamster cholangiocarcinoma (ChC) model, we evaluated the immunohistochemical expression pattern of TrxR in precancerous lesions and ChCs as well as in normal bile ducts. The goal of this study was to determine the potential role and importance of TrxR in cholangiocarcinogenesis. For the ChC model, we obtained liver tissue specimens with dysplastic bile ducts prior to the development of ChC 8... -
Mediastinal lymphoma in a young Turkish Angora cat
Kyoung-Won Seo, Ul-Soo Choi, Bo-Kyoung Bae, Mi-Sun Park, Cheol-Yong Hwang, Dae-Yong Kim, Hwa-Young Youn 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 18 199-201 (3 pages)
containing variable sized lymphocytes with frequent mitotic figures and prominent nucleoli. The feline leukemia virus and feline immunodeficiency virus tests were negative. The cat was euthanized at his owner’s request and a necropsy was performed. A mass was detected on the mediastinum and lung lobes. A histopathology evaluation confirmed the mass to be a lymphoma. Immunohistochemistry revealed the mass to be CD3 positive. In conclusion, the cat was diagnosed as a T-cell mediastinal lymphoma. -
Topical application of epidermal growth factor accelerates wound healing by myofibroblast proliferation and collagen synthesis in rat
Young-Bae Kwon, Hyun-Woo Kim, Dae-Hyun Roh, Seo-Yeon Yoon, Rong-Min Baek, Jeum -Yong Kim, HaeYong Kweon, Kwang-Gill Lee, Young-H 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 2 105-109 (5 pages)
Recombinant human epidermal growth factor (rhEGF) stimulates the proliferation and migration of epithelial cells in human cell culture systems and animal models of partial-thickness skin wounds. This study investigated the effect of a topical rhEGF ointment on the rate of wound healing and skin re-epithelialization in a rat full thickness wound model, and verified whether or not the rhEGF treatment affected both myofibroblast proliferation and collagen synthesis in the dermis. When rhEGF (10... -
Epitheliotropic cutaneous lymphoma (mycosis fungoides)in a dog
Dong Ha Bhang, Ul Soo Choi, Min Kyu Kim , Eun-Hwa Choi , Min-Soo kang , Cheol-Yong Hwang, Dae-Yong Kim , Hwa Young Youn, Chang W 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 1호 20 97-99 (3 pages)
epitheliotropic T cell cutaneous lymphoma by histopathology and immunochemical stain.In serum chemistry, the dog had a hypercalcemia (15.7 mg/dl)and mild increased alkaline phosphatase (417U/l). Immunohistochemistry was performed to detect parathyroid hormone-related peptide (PTH-rP)in epitheliotropic cutaneous lymphoma tissues but the neoplastic cells were not labeled with anti-PTH-rP antibodies. The patient was treated with prednisolone and isotretinoin. However, the dog died unexpectedly. -
Concurrent response to challenge infection with Cryptosporidium parvum in immunosuppressed C57BL/6N mice
Chan-Gu Surl , Hyeon-Cheol Kim 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 1호 8 47-51 (5 pages)
We investigated the response to challenge infection with Cryptosporidium parvum oocysts in immunosuppressed C57BL/6N mice.In the primary infection, fecal oocyst shedding and parasite colonization were greater in immunosuppressed mice than in nonimmunosuppressed mice.Compared with primary infection, challenge infection with C.parvum didn 't show any oocyst shedding and parasite colonization.Especially, oocyst shedding and parasite colonization from the mice infected with heat- killed oocysts were... -
Histopathological changes of testes and eyes by neutron irradiation with boron compounds in mice
Yeon-Joo Kim, Won-Ki Yoon, SI-Yun Ryu, Ki-Jung Chun, Hwa-Young Son, Sung-Whan Cho 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 1호 3 19-23 (5 pages)
This study was performed to investigate the biological effects of boron neutron capture therapy (BNCT)on the testes and eyes in mice using HANARO Nuclear Reactor, Korea Atomic Energy Research Institute.BNCT relies on the high capacity of 10B in capturing thermal neutrons. Sodium borocaptate (BSH, 75 ppm, iv)and borono-phenylalanine (BPA, 750 ppm, ip)have been used as the boron delivery agents.Mice were irradiated with neutron(flux:1.036739E +09, Fluence 9.600200E+12)by lying flatpose for 30 (10... -
Comparison of an enzyme-linked immunosorbent assay with serum neutralization test for serodiagnosis of porcine epidemic diarrhea virus infection
Jin Sik Oh, Dae Sub Song, Jeong Sun Yang, Ju Young Song, Hyoung Joon Moon, Tae Yung Kim, Bong Kyun 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 4호 14 349-352 (4 pages)
An indirect porcine epidemic diarrhea (PED)virus (PEDV)enzyme-linked immunosorbent assay (ELISA) was compared with the serum neutralization (SN)test by testing 46 samples from experimentally infected sows,73 samples from naive sows,and 1,024 field sow samples from 48 commercial swine farms of undefined PED status. The SN test and the ELISA were performed using PEDV, KPEDV-9 strain.Viral proteins as a coating antigen of PEDV ELISA were extracted from the cytoplasm of PEDV-infected Vero cells... -
CT myelography of the thoraco-lumbar spine in 8 dogs with degenerative myelopathy
Jeryl C. Jones, Karen D. Inzana, John H. Rossmeisl, Robert L. Bergman, Tana Wells, Katherine Butler 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 4호 13 341-348 (8 pages)
CT myelography of the T11-L2 region was performed in 8 large-breed dogs with a clinical diagnosis of degenerative myelopathy (DM) and 3 large-breed dogs that were clinically normal. CT myelographic characteristics were recorded for each dog, at each disc level. Area measurements of the spinal cord, dural sac, vertebral canal, and vertebral body were recorded at 4 slice locations for each disc level. Mean area ratios were calculated and graphically compared, by slice location and group. In all...


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