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Mechanism of Membrane Hyperpolarization by Extracellular K+ in Resistance-sized Cerebral Arterial Muscle Cell of Rabbit
SeHoonKim, KunMooChoi, HoeSukKim, ByeongHwaJeon, SeokJongChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 1 1-10 (10 pages)
find out the mechanism of vascular relaxation by extracellular K concentration ([K]o) in the cerebral resistant arteriole from rabbit. Single cells were isolated from the cerebral resistant arteriole, and using voltage-clamp technique barium-sensitive K currents were recorded, and their characteristics were observed. Afterwards, the changes in membrane potential and currents through the membrane caused by the change in [K]o was observed. In the smooth muscle cells of... -
Effects of Prostaglandin E2 on the Spontaneous Contractions and Electrical Activities of the Antral Circular Muscle in Guinea-pig Stomach
JongYoonKim, SungJoonKim, TongMookKang, SangJinLee, JaeYeoulJun, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 11 361-368 (8 pages)
The spontaneous contractions of gastric smooth muscles are regulated by slow waves, which are modulated by both nervous system and humoral agents. This study was designed to examine the effects of prostaglandin E2 (PGE2) on the contractile and electrical activities of antral smooth muscles in guinea-pig stomach, using an intracellular recording technique. To elucidate the underlying mechanism for its effect on contractility, ionic currents were also measured using a whole-cell patch clamp... -
Differential Effect of Homocysteic Acid and Cysteic Acid on Changes of Inositol Phosphates and [Ca2+]i in Rat Cerebellar Granule Cells
Won-KiKimYoung-SookPae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 5 41-48 (8 pages)
of physiological sa1t solution maintained at 370C, and aerated with 95% 02/5% CO2. Isometric myography was -
Combination of Electroconvulsive Therapy and Clozapine in Treatment-Resistant Schizophrenia
Jung Hyun Kim, Tak Youn, Jun Gwon Choi, Seong Hoon Jeong, Hee Yeon Jung, Yong Sik Kim, In Won Chung 대한신경정신의학회 Psychiatry Investigation 7 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 13 829-835 (7 pages)
during five years of pre-determined period were recruited from Electronic Medical Record. Clinical effects of acute ECT on psychotic symptoms were investigated. We also tried to identify predictive variables requiring maintenance treatment of ECT. Results_Fourteen patients received ECT and clozapine and sixteen were treated with clozapine alone. In the ECT group, which could be refined as clozapine-resistance, PANSS total score was significantly reduced by 19.0±9.9 points, corresponding to a... -
Neural Substrates of Motor Imagery: Event-related Functional MRI Study
Seung-Schik Yoo, Byung Gil Choi, Kyu-In Chung, Chang-Uk Lee 대한신경정신의학회 신경정신의학 10 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 6호 25 1247-1256 (10 pages)
연구목적: 본 연구의 목적은 가상운동 과정시 대뇌 어느 부위가 활성화되는지를 알아보기 위하여 사건-관련 기능적 자기 공명영상을 통해 평가하였다. 방 법: 9명의 오른손잡이 정상인들에게 뇌 전 영역을 포괄한 일련의 T2강조 자기공명 영상을 얻기 위해 1.5 Tesla 자 기공명 영상장치를 사용하였다. 음성 자극 신호에 따라 오른손을 쥐는 상상을 하게 한 후, 그 결과 발생하는 가상 운동과 연관된 혈중 산화 수준-의존성 신호 변화들을 측정하였다. 결 과: 측정된 자료를 group 분석한 결과 내측 상부 전두회, 설상엽, 도, 중 /... -
Cellular Mechanism of Nicotine-mediated Intracellular Calcium Homeostasis in Primary Culture of Mouse Cerebellar Granule Cells
김원기(Won-Ki Kim), 배영숙(Young-Sook Pae) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1996, 제 32권 제 1호 2 13-22 (10 pages)
in a specific developmental stage and involved in the regulation of intracellular calcium homeostasis. Nicotine-mediated calcium responses were measured using 45Ca2+ or fluorometrically using the calcium-sensitive fluorescent dye fura-2. Maximal uptake of 45Ca2+ evoked by nicotine in mouse cerebellar granule cells were revealed 8 ~ 12 days in culture. In contrast, nicotine did not alter the basal 45Ca2+ uptake in cultured glial cells. In cerebellar granule cells nicotine-evoked 45Ca2+ uptake was... -
Effect of Ischemic Preconditioning on the Oxygen Free Radical Production in the Post-ischemic Reperfused Heart
박종완(Jong-Wan Park), 김영훈(Young-Hoon Kim), 엄창섭(Chang-Sub Uhm), 배재문(Jae-Moon Bae), 박찬웅(Chan-Woong Park), 김명석(Myung-Suk Kim) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1994, 제 30권 제 3호 6 321-330 (10 pages)
peroxidation of myocardial tissue as estimated from malondialdehyde production was markedly reduced. PC did not affect the activity of xanthine oxidase which is a major source of oxygen radicals in the ischemic rat hearts, but the myocardial content of hypoxanthine (a substrate for xanthine oxidase) was much lower in PC hearts. It is suggested from these results that PC brings about significant myocardial protection in ischemic-reperfused heart and this effect may be related to the suppression o... -
Enhanced Efficacy of the Commissural Transmission between Lateral Giants in the Sensitization of Crayfish Escape Behavior
C.Lee, Sun-Hee 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 11 291-300 (10 pages)
efficacy of commissural transmission between lateral giants, as indicated by a significant reduction of commissural delay. This effect was blocked by an octopamine antagonist phentolamine, suggesting a specific action of octopamine on the octopamine receptor present on LGs. These observations suggest that both traumatic shocks and octopamine may cause a rather broad alteration in the excitability of the crayfish nervous system that contributes to the sensitization of the LG escape response. -
Enhanced Expression of Angiotensinogen mRNA in Rat Central and Peripheral Tissues Following Hemorrhage
Do, Eun-Ju, Yang, Eun-Kyoung, Kim, Kyung-Soon, Kim, Suk-Hee, Park, Yoon-Yub, Ahn, Dong-Kuk, Park, Jae-Sik, Lee, Won-Jung 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 8 259-268 (10 pages)
The renin-angiotensin system plays an important role in the regulation of blood pressure and in body fluid homeostasis. There is increasing evidence for generation of endogenous angiotensin II in many organs and for its role in paracrine functions. Studies were designed to investigate whether hemorrhage produces rapid changes in the gene expression of angiotensinogen in peripheral and brain tissues. Wistar rats received saline drinking water for 7 days, were bled at a rate of 3mlkg-1 min-1 for 7... -
Contractile and Electrical Responses of Guinea-pig Gastric Smooth Muscle to Bradykinin
Kim, Chul-Soo, Jun, Jae-Yeoul, Kim, Sung-Joon, So, In-Suk, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 5 233-242 (10 pages)
been shown to exhibit an array of biological activities including relaxation/contraction of various smooth muscles. In order to investigate the effects of bradykinin on the contractility and the electrical activity of antral circular muscle of guinea-pig stomach, the isometric contraction and membrane potential were recorded. Also, using standard patch clamp technique, the Ca2+-activated K currents were recorded to observe the change in cytosolic Ca2+ concentration. 0.4 μM bradykinin induced a...


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