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Characteristics of Ca2+ Stores in Rabbit Cerebral Artery Myocytes
SungJoonKim, JinKyungKim, InsukSo, SukHyoSuh, SangJinLee, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 6 313-322 (10 pages)
In a myocyte freshly isolated from rabbit cerebral artery, the characteristics of Ca2 release by histamine or caffeine were studied by microspectrofluorimetry using a Ca2-binding fluorescent dye, fura-2. Histamine (5 ㄍM) or caffeine (10 mM) induced a phasic rise of cytoplasmic free Ca2 concentration ([Ca2]c) which could occur repetitively with extracellular Ca2 but only once or twice in Ca2-free bathing solution. Also, the treatment with... -
Comparison of Somatostatin and Morphine Action on the Responses of Wide Dynamic Range Cells in the Dorsal Horn to Peripheral Noxious Mechanical and Heat Stimulation in Cats
SungJunJung, YoungInChoi, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 3 155-163 (9 pages)
The purpose of present study was to compare the effects of somatostatin (SOM) and morphine (Mor) on the responses of wide dynamic range (WDR) cells to peripheral noxious stimulation. Single neuronal activity was recorded with a carbon-filament electrode at the lumbosacral enlargement of cat spinal cord. After identifying WDR cells, their responses to peripheral noxious mechanical or thermal stimuli were characterized and the effects of SOM and Mor, applied either iontophoretically or... -
Ca2+ Signalling in Endothelial Cells Role of Ion Channels
BerndNilius, FelixViana, MasahiroKamouchi, CristinaFasolato, JanEggermont, GuyDroogmans 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 1 133-145 (13 pages)
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Effects of Histamine H2-Receptor Stimulation on Mg2+ Efflux in Perfused Guinea Pig Heart
Hyung-SubKang, Sung-EunChang, Chang-WonKang, Soo-WanChae, Jin-SangKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 6 49-54 (6 pages)
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Sensory Inputs to Upper Cervical Spinal Neurons Projecting to Midbrain in Cats
JongHoKim, Han-SeongJeong, Jong-SeongPark, Jong-KeunKim, Sah-HoonPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 2 9-19 (11 pages)
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기니픽 심장과 심근 세포에서 α1-Adrenergic 자극에 의한 Mg2+ 유리조절 Regulation of Mg2+ Release in Guinea Pig Heart and Isolated Ventricular Myocytes by Ձ1-Adrenergic Stimulation
강형섭, 장성은, 김진상, Hyung-SubKang, Sung-EunChang, Jin-SangKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 13 717-730 (14 pages)
cellular organisms. Although the biological chemistry and the physiological roles of the magnesium ion were well known, the regulation of intracellular Mg2 in mammalian cells is not fully understood. More recently, however, the mechanism of Mg2 mobilization by hormonal stimulation has been investigated in hearts and in myocytes. In this work we have investigated the regulation mechanism responsible for the Mg2 mobilization induced by α1-adrenoceptor stimulation in perfused... -
Effect of pH on the ATP-sensitive K+ Channel in Aortic Smooth Muscle Cells from Rats
SeHoonKim, IlSuKim, HoeSukKim, ByeongHwaJeon, SeokJongChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 11 555-563 (9 pages)
The effects of pH on K currents were investigated in single smooth muscle cells isolated from the thoracic aorta of Wistar-Kyoto rats. Whole-cell K currents were recorded in the conventional configuration of the voltage-clamp technique. Pinacidil (10uM) activated the whole-cell current and the pinacidil-activated current was completely inhibited by glibenclamide (10uM) , an inhibitor of ATP-sensitive K channel (KATP channel). Pinacidil-activated current was reversed at near... -
Association of Dexamethasone-induced Apoptosis and G1-Arrest of Human Leukemic CEM Cells with Polyamine Deficit
Sang-HyunChoi, Jung-AeLee, Yang-SeokChae, Bon-HongMin, Yeon-SookChun, Boe-GwunChun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 12 457-466 (10 pages)
The effects of DFMO or/and putrescine on the dexamethasone-induced apoptosis of CEM cells were studied to investigate the role of polyamines in anti-leukemic glucocorticoid action. Dexamethasone- induced apoptosis was preceded by significant decreases of cellular polyamine contents and putrescine uptake activity. But DFMO produced decreases of putrescine and spermidine contents and marked increase of putrescine uptake activity, but did not induce apoptosis. However, dexamethasone and DFMO,... -
개 하부식도괄약근의 비아드레날린성, 비콜린성 이완반응에 있어서 Cyclic Nucleotide의 역할 Regulatory Role of Cyclic Nucleotides in Non-Adrenergic Non-Cholinergic Relaxation of Lower Esophageal Sphincter from Dogs
김영태, 임병용, YoungTaeKim, ByungYongRhim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.3 9 303-313 (11 pages)
The role of the lower esophageal sphincter(LES) is characterized by the ability to maintain tone and to relax allowing the passage of a bolus. It is known that LES relaxation during swallowing may be induced by the cessation of the tonic neural excitation and the activation of non-adrenergic, non-cholinergic(NANC) inhibitory neurons. Furthermore, it is generally accepted that the relaxation of the smooth muscle is mediated primarily by the elaboration of adenosine 3',5'-cyclic...


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