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Inhibition of β-amyloid1-40 Peptide Aggregation and Neurotoxicity by Citrate
YongHoonPark, Young-JinKim, IlHongSon, HyunDukYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.4 2 273-279 (7 pages)
The accumulation of Ղ-amyloid (AՂ) aggregates is a characteristic of Alzheimer's disease (AD). Furthermore, these aggregates have neurotoxic effects on cells, and thus, molecules that inhibit AՂ aggregate formation could be valuable therapeutics for AD. It is well known that aggregation of AՂ depends on its hydrophobicity, and thus, in order to increase the hydrophilicity of AՂ, we considered using citrate, an anionic surfactant with three carboxylic acid groups. We... -
Differential Activation of Ras/Raf/MAPK Pathway between Heart and Cerebral Artery in Isoproterenol-induced Cardiac Hypertrophy
HyunjuKim, NariKim, HyunJoo, JaeBoumYoum, WonSunPark, MohamedWarda, SunghyunKang, VuThiThu, TranMinhKhoa, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.5 7 299-304 (6 pages)
Cardiac hypertrophy contributes an increased risk to major cerebrovascular events. However, the molecular mechanisms underlying cerebrovascular dysfunction during cardiac hypertrophy have not yet been characterized. In the present study, we examined the molecular mechanism of isoproterenol (ISO)-evoked activation of Ras/Raf/MAPK pathways as well as PKA activity in cerebral artery of rabbits, and we also studied whether the activations of these signaling pathways were altered in cerebral artery,... -
Nitric Oxide-cGMP-Protein Kinase G Pathway Contributes to Cardioprotective Effects of ATP-Sensitive K+ Channels in Rat Hearts
DangVanCuong*, NariKim*, HeeCheolCho, EuiyongKim, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.2 5 95-100 (6 pages)
been shown to contribute cardiac protective effect to reduce heart I/R-induced infarction. The present investigation tested the hypothesis that KATP channels attenuate DNA strand breaks and oxidative damage in an in vitro model of I/R utilizing rat ventricular myocytes. We estimated DNA strand breaks and oxidative damage by mean of single cell gel electrophoresis with endonuclease III cutting sites (comet assay). In the I/R model, the level of DNA damage increased massively. Preconditioning with... -
Cocaine-induced Changes in Functional Connectivities between Simultaneously Recorded Single Neurons in the SI Cortex and the VPL Thalamus of Conscious Rats
Shin, Hyung-Cheul, Park, Hyoung-Jin, Oh, Yang-Seok, Chapin, John K. 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 1호 8 79-92 (14 pages)
between pairs of simultaneously recorded neurons. Among 101 neuronal pairs analyzed, 22.7% showed correlations indicative of various functional connections among the cortical cells, two corticothalamic interactions and one thalamocortical excitatory interaction. There were also 15 cofiring activities among SI cortical cells. These functional connectivities appeared to be modulated (weakened, abolished, or strengthened) during the 5 to 30 min following cocaine injection. The effects of saline wer... -
Children with Disability and Communicational Development Support through Dousa-hou
KUMAR Surender, CHO Joohee, Oh Kunseok 아시아장애사회학회 아시아장애사회학연구 10 Pages
아시아장애사회학회 아시아장애사회학연구 2014, 제 13권 1 1-10 (10 pages)
The results of Questionnaire for Developmental Changes showed that the psychological rehabilitation method Dousa-hou could support and promote most the body posture and communication related factors as volunteer body movements, behavior control, health maintenance, emotion expression, initiative & appearance, speech and communication, and social interaction factors by the practice of Dousa- hou training in 3-days long camps in Malaysian context. -
Independent Living and Japanese Psychological Rehabilitation Program -A Famly based Program for People with Disability-
ASGHAR Dadkhah, SURENDER Kumar, SUSUNU Harizuka 아시아장애사회학회 아시아장애사회학연구 12 Pages
아시아장애사회학회 아시아장애사회학연구 2011, 제 11권 22 237-248 (12 pages)
Psychologists have contributed to programs that are helping people change their feelings, emotions, and behavior instead of just suppressing symptoms. There have been lots of improvements in psychological interventions working with people with disability and serious mental disorders. In particular, a number of treatment programs are drawing on the work of psychologists and their method encourages people to learn about their own body and mind and demonstrate social skills that allow them to... -
A Study on the Facilitation of the Cooperation of Industry-Academia
Ji-Sun Chung, Nam chul Lee 한국성인교육학회 한국성인교육학회 학술대회지 15 Pages
한국성인교육학회 한국성인교육학회 학술대회지 2005년호 19 201-215 (15 pages)
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They Do, but I Don’t: Relationships Among AIDS Stigma Gap, AIDS Knowledge, and Attitude Toward AIDS-Related Issues
Seyeon Keum, Byoungkwan Lee, Hyun Jung Oh 한국헬스커뮤니케이션학회 헬스커뮤니케이션연구 43 Pages
한국헬스커뮤니케이션학회 헬스커뮤니케이션연구 2015, Vol.13 4 101-143 (43 pages)
This study examines whether there is a significant AIDS stigma gap among Korean people, and reveals causes and consequences of this perceptual gap. An analysis of the survey data collected to evaluate the impact of 2011 AIDS campaign in Korea revealed a perceptual gap between personal stigma and attributed stigma. AIDS knowledge was a significant factor in reducing this perceptual disparity. AIDS stigma gap significantly predicted public support on regulating prostitution but not on restricting... -
Development of Play in Pre-Schoolers: Video-Based Analysis of Free and Structured Toy Play Scenario
Megha Mohan, Reenu Celshiya. A, Jayashree S. Bhat 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 23 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2022, Vol.16 No.3 3 47-69 (23 pages)
Play is a universal code, which mirrors the all-round development of a child. Play development reflects the emergence of early cognitive skills in children. The current study profiles the developmental trends of different types of play during the free and structured play scenario in South India. The sample included 48 pre-school children, aged between 3.6 to 5.6 years. Children’s play was recorded in two scenarios, which included free Play (spontaneous Play without any restrictions) and... -
The Project Approach on Environmental Education: An Action Research for Children’s Social-Emotional Development
Ulil Abshor 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 20 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2017, Vol.11 No.1 1 1-20 (20 pages)
The aim of this study is to increase children’s social-emotional development using project approach on early childhood environmental education. The researcher uses applied classroom action research method to explore the project approach on environmental education as multidimensional approach. The project approach is in-depth investigation to a topic which has three phases; 1) planning and getting started, 2) developing project, and 3) reflection and conclusion. This study involved collaborators...


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