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391.

Effects of Cl⁣ Channel Blockers on the Cardiac ATP-sensitive K+ Channel

Yong-GeunKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 8 305-313 (9 pages)

Yong-GeunKwak 저
...
- 3,000원
To explore whether Cl⁣ channel blockers interact with the ATP-sensitive K⁢ (KATP) channel, I have examined the effect of two common Cl⁣ channel blockers on the KATP channel activity in isolated rat ventricular myocytes using patch clamp techniques. In inside-out patches, 4,4'-diisothio-cyanatostilbene- 2,2'-disulfonic acid (DIDS) and niflumic acid applied to bath solution inhibited the KATP channel activity in a concentration-dependent manner with IC50 of 0.24 and 927μM,...
392.

Hypothermic Preconditioning Lowers the Incidence of Hypothermic Arrest in Neonatal Rat

SungSookPark, HeungSikNa, HyunJungNam, SeungKilHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 14 231-236 (6 pages)

SungSookPark, HeungSikNa, HyunJungNam, SeungKilHong 저
...
- 3,000원
significant level of HSP72 expressions. To assess the cardioprotective effect of HSP72 against hypothermic cardiac arrest, we compared the proportion of recovery from the arrest between control and preconditioned (PREC) animals. Control animals were subjected to 20-min hypothermic insult, while PREC group was preconditioned by 10-min hypothermic insult 8 hours before the 20-min test hypothermic insult. Resuscitation rate from cardiac arrest induced by the 20-min hypothermic insult in PREC group...
393.

Properties of Spontaneous Activity in Gastric Smooth Muscle

H.Suzuki, Y.Yamamoto, G.D.S.Hirst 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 1 119-125 (7 pages)

H.Suzuki, Y.Yamamoto, G.D.S.Hirst 저
...
- 3,000원
Mammalian gastric smooth muscles generate spontaneous rhythmic contractions which are associated with slow oscillatory potentials (slow waves) and spike potentials. Spike potentials are blocked by organic Ca2⁢-antagonists, indicating that these result from the activation of L-type Ca2⁢-channel. However, the cellular mechanisms underlying the generation of slow wave remain unclear. Slow waves are insensitive to Ca2⁢-antagonists but are blocked by metabolic inhibitors or low...
394.

Involvement of Adenosine in Cardioprotective Effect of Catecholamine Preconditioning in Ischemia-Reperfused Heart of Rat

Young-hoonKim, Chan-hyungKim, Gi-taeKim, In-kyuKim, Jong-wanPark, Myung-sukKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 12 753-761 (9 pages)

Young-hoonKim, Chan-hyungKim, Gi-taeKim, In-kyuKim, Jong-wanPark, Myung-sukKim 저
...
- 3,000원
㄂-agonist, isoproterenol(10⁣9∼10⁣7 M) markedly improved the post-ischemic mechanical function and reduced the lactate dehydrogenase release. Similar cardioprotective effect was observed with an ㄁-agonist, phenylephrine pretreatment, but much higher concentration(10⁣4 M) was needed to achieve the same degree of cardioprotection. The cardioprotective effects of isoproterenol and phenylephrine pretreatments were blocked by a ㄂1-adrenergic receptor antagonist,...
395.

Moderate Elevation of Extracellular K+ Concentration Induces Vasorelaxation in Isolated Rat, Rabbit and Human Cerebral Arteries Role of Na Pump and Ba-Sensitive Process

DongHoKim, SungJoonKim, SangJinLee, SungJinPark, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 7 705-714 (10 pages)

DongHoKim, SungJoonKim, SangJinLee, SungJinPark, KiWhanKim 저
...
- 3,000원
Cerebral blood vessels relax when extracellular K⁢ concentrations ([K⁢])e are elevated moderately (2∼15 mM, K⁢-induced vasorelaxation). We have therefore studied the underlying mechanism for this K⁢- induced vasorelaxation in the isolated middle cerebral arteries (MCAs). The effects of ouabain and Ba2⁢ on K⁢-induced vasorelaxation were examined to determine the role of sodium pump and/or Ba-sensitive process (possibly, inward rectifier K current) in the...
396.

Effects of Neonatal Footshock Stress on Glucocorticoid and 5- HT2A/2C Receptor Bindings and Exploratory Behavior

DongGooKim, SeoulLee, DongWonKang, JongSuLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 4 677-685 (9 pages)

DongGooKim, SeoulLee, DongWonKang, JongSuLim 저
...
- 3,000원
To investigate the effects of neonatal stress on behavior and neurochemistry, rats were exposed to the footshock stress on postnatal day (PND) 14 or PNDs 14 and 21. Rats were exposed to uncontrollable electric shocks delivered to the floor with a constant current (0.8 mA) for 5 sec period. Daily sessions consisted of 60 trials on a random time schedule with an average of 55 sec. The first exposure to footshocks on PND 14 decreased body weight gain for 1 day. However, the second exposure to...
397.

The Effects of Intracellular Monocarboxylates on the ATP-sensitive Potassium Channels in Rabbit Ventricular Myocytes

NariKim, JinHan, Eui-YongKim, Won-KyungHo, YungE.Earm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 6 581-589 (9 pages)

NariKim, JinHan, Eui-YongKim, Won-KyungHo, YungE.Earm 저
...
- 3,000원
A regulating mechanism of the ATP-sensitive potassium channels (KATP channels) is yet to fully explained. This study was carried out to investigate the effects of intracellular application of monocarboxylates (acetate, formate, lactate, and pyruvate) on KATP channels in isolated rabbit ventricular myocytes. Single channel currents of KATP channels were recorded using the excised inside-out or permeabilized attached (open-cell) patch-clamp technique at room temperature. Intracellular application...
398.

Regulation of Salt and Volume Transport along the Nephron during Acute Systolic Hypertension

AliciaA.McDonough, YibinZhang, ClaraE.Magyar, AustinK.Mircheff 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 1 541-547 (7 pages)

AliciaA.McDonough, YibinZhang, ClaraE.Magyar, AustinK.Mircheff 저
...
- 3,000원
399.

Cardioprotective Effects of Low Dose Bacterial Lipopolysaccharide May Not Be Directly Associated with Prostacyclin Production

Chang-HyunMoon, JiYoungKim, SooHwanLee, EunJooBaik 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 8 331-343 (13 pages)

Chang-HyunMoon, JiYoungKim, SooHwanLee, EunJooBaik 저
...
- 4,200원
Sublethal dose of bacterial lipopolysaccharide (LPS) would induce protection against cardiac ischemic/ reperfusion (I/R) injury. This study examines the following areas: 1) the temporal induction of the cardioprotection produced by LPS; and 2) the relations between a degree of protection and the myocardial prostacyclin (PGI2) production. Rats were administered LPS (2 mg/kg, i.v.), and hearts were removed 1, 4, 8, 14, 24, 48, 72,and 96 h later. Using Langendorff apparatus, haemodynamic...
400.

Intracisternal Antidepressants Suppressed the Nociceptive Jaw Opening Reflex in Freely Moving Rats

Dong-KukAhnYun-SookKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 5 307-312 (6 pages)

Dong-KukAhnYun-SookKim 저
...
- 3,000원
of recovery from surgery, digastric electromyogram (dEMG) of freely moving rats was recorded. Electrical shocks (200 Ռsec duration, 0.5-2 mA intensity) were delivered at 0.5 Hz to the dental pulp every 2 minute. Intracisternal administration of 15 Ռg imipramine suppressed dEMG elicited by noxious electrical stimulation in the tooth pulp to 76±6% of the control. Intracisternal administration of 30 Ռg desipramine, nortriptyline, or imipramine suppressed dEMG remarkably to 48±2,...

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