학지사 뉴논문

총 1,767건 검색

본문검색 결과만 보기

정확도순

최신순

등재순

발행기간

전체
최근 1년
최근 3년
직접입력

적용하기

본문검색

포함

제외

10개씩

391.

Requirement of Pretone by Thromboxane A2 for Hypoxic Pulmonary Vasoconstriction in Precision-cut Lung Slices of Rat

SuJungPark, HaeYoungYoo, HyeJinKim, , , JinKyoungKim, Yin-HuaZhang, SungJoonKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 9 59-64 (6 pages)

SuJungPark, HaeYoungYoo, HyeJinKim, , , JinKyoungKim, Yin-HuaZhang, SungJoonKim, 저
...
- 3,000원
Hypoxic pulmonary vasoconstriction (HPV) is physiologically important response for preventing mismatching between ventilation and perfusion in lungs. The HPV of isolated pulmonary arteries (HPV-PA) usually require a partial pretone by thromboxane agonist (U46619). Because the HPV of ventilated/perfused lungs (HPV-lung) can be triggered without pretone conditioning, we suspected that a putative tissue factor might be responsible for the pretone of HPV. Here we investigated whether HPV can be also...
392.

Acute Toxicity and General Pharmacological Action of QGC EXT

JongMiLee, WiJoonIm, YoonJinNam, KyungHoonOh, JaeChunLim, WanKyunnWhang, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 8 49-57 (9 pages)

JongMiLee, WiJoonIm, YoonJinNam, KyungHoonOh, JaeChunLim, WanKyunnWhang, UyDongSohn 저
...
- 3,000원
central controlled behavior responses, and peripheral organs including blood pressure, heart rate, respiration and gastrointestinal system, We found that there were no significant changes in body temperature, locomotors activity, stereotyped behaviors, sleeping time, and convulsion. In other studies, writhing reaction, normal body temperature, there did not appear to be any changes. The large intestine movement and electrical field stimulation-induced contraction was not changes by its EXT. In...
393.

Vasorelaxing Activity of Ulmus davidiana Ethanol Extracts in Rats: Activation of Endothelial Nitric Oxide Synthase

EunJungCho, MyoungSooPark, SahngSeopKim, GunKang, SungaChoi, YooRhanLee, SeokJongChang, KwonHoLee, SangDoLee, JinBongPark, ByeongHwaJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 4 339-344 (6 pages)

EunJungCho, MyoungSooPark, SahngSeopKim, GunKang, SungaChoi, YooRhanLee, SeokJongChang, KwonHoLee, SangDoLee, JinBongPark, ByeongHwaJeon 저
...
- 3,000원
cultured cells, isometric tension recording and blood pressure analysis, respectively. Low dose of UD (10∼100Ռg/ml) did not affect endothelial cell viability, but high dose of UD reduced cell viability. UD induced vasorelaxation in the range of 0.1∼10Ռg/ml with an ED50 value of 2Ռg/ml. UD-induced vasorelaxation was completely abolished by removal of the endothelium or by pre-treatment with L-NAME, an inhibitor of nitric oxide synthase. UD inhibited calcium influx induced by...
394.

A Computational Model of Cytosolic and Mitochondrial [Ca2＋] in Paced Rat Ventricular Myocytes

JaeBoumYoum, SeongWooChoi, ChangHanJang, HyoungKyuKim, ChaeHunLeem, NariKim, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 23 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.4 5 217-239 (23 pages)

JaeBoumYoum, SeongWooChoi, ChangHanJang, HyoungKyuKim, ChaeHunLeem, NariKim, JinHan 저
...
- 5,200원
We carried out a series of experiment demonstrating the role of mitochondria in the cytosolic and mitochondrial Ca2＋ transients and compared the results with those from computer simulation. In rat ventricular myocytes, increasing the rate of stimulation (1∼3 Hz) made both the diastolic and systolic [Ca2＋] bigger in mitochondria as well as in cytosol. As L-type Ca2＋ channel has key influence on the amplitude of Ca2＋-induced Ca2＋ release, the relation between stimulus frequency and the...
395.

Direct Corticosteroid Modulation of GABAergic Neurons in the Anterior Hypothalamic Area of GAD65-eGFP Mice

SeungYubShin, TaeHeeHan, SoYeongLee, SeongKyuHan, JinBongPark, FerencErdelyi, GaborSzabo, PanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.3 7 163-169 (7 pages)

SeungYubShin, TaeHeeHan, SoYeongLee, SeongKyuHan, JinBongPark, FerencErdelyi, GaborSzabo, PanDongRyu 저
...
- 3,000원
with vehicle, corticosterone, or corticosterone with spironolactone (GR-dominant group; 64 vs. 11∼14%, p＜0.01 by ՗2-test). Taken together, the results show that the corticosteroid receptors are expressed on the GABAergic neurons in the AHA, and can mediate the corticosteroid-induced plasticity in the firing pattern of these neurons. This study newly provides the experimental evidence for the direct glucocorticoid modulation of GABAergic neurons in the AHA in the vicinity of the PVN.
396.

Arginase Inhibition by Ethylacetate Extract of Caesalpinia sappan Lignum Contributes to Activation of Endothelial Nitric Oxide Synthase

WoosungShin, ToDaoCuong, JeongHyungLee, ByungsunMin, ByeongHwaJeon, HyunKyoLim, SungwooRyoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.3 1 123-128 (6 pages)

WoosungShin, ToDaoCuong, JeongHyungLee, ByungsunMin, ByeongHwaJeon, HyunKyoLim, SungwooRyoo 저
...
- 3,000원
Caesalpinia sappan (C. sappan) is a medicinal plant used for promoting blood circulation and removing stasis. During a screening procedure on medicinal plants, the ethylacetate extract of the lignum of C. sappan (CLE) showed inhibitory activity on arginase which has recently been reported as a novel therapeutic target for the treatment of cardiovascular diseases such as atherosclerosis. CLE inhibited arginase II activity prepared from kidney lysate in a dose-dependent manner. In HUVECs,...
397.

Effects of Isoflurane Anesthesia on Post-Anesthetic Sleep-Wake Architectures in Rats

Hwan-SooJang, Ji-YoungJung, Kwang-HoJang, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 7 291-297 (7 pages)

Hwan-SooJang, Ji-YoungJung, Kwang-HoJang, Maan-GeeLee 저
...
- 3,000원
The sleep homeostatic response significantly affects the state of anesthesia. In addition, sleep recovery may occur during anesthesia, either via a natural sleep-like process to occur or via a direct restorative effect. Little is known about the effects of isoflurane anesthesia on sleep homeostasis. We investigated whether 1) isoflurane anesthesia could provide a sleep-like process, and 2) the depth of anesthesia could differently affect the post-anesthesia sleep response. Nine rats were treated...
398.

Neuroprotective Effect of Visnagin on Kainic Acid-induced Neuronal Cell Death in the Mice Hippocampus

Min-SooKwon, Jin-KooLee, Soo-HyunPark, Yun-BeomSim, Jun-SubJung, Moo-HoWon, Seon-MiKim, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 2 257-263 (7 pages)

Min-SooKwon, Jin-KooLee, Soo-HyunPark, Yun-BeomSim, Jun-SubJung, Moo-HoWon, Seon-MiKim, Hong-WonSuh 저
...
- 3,000원
as a treatment for low blood-pressure and blocked blood vessel contraction by inhibition of calcium influx into blood cells. However, the neuroprotective effect of visnagin was not clearly known until now. Thus, we investigated whether visnagin has a neuroprotective effect against kainic acid (KA)-induced neuronal cell death. In the cresyl violet staining, pre-treatment or post-treatment visnagin (100 mg/kg, p.o. or i.p.) showed a neuroprotective effect on KA (0.1Ռg) toxicity. KA-induced...
399.

Calcium Sensitization Induced by Sodium Fluoride in Permeabilized Rat Mesenteric Arteries

EnyueYang, JoonYongCho, UyDongSohn, InKyeomKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.1 8 51-57 (7 pages)

EnyueYang, JoonYongCho, UyDongSohn, InKyeomKim, 저
...
- 3,000원
It was hypothesized that NaF induces calcium sensitization in Ca2＋-controlled solution in permeabilized rat mesenteric arteries. Rat mesenteric arteries were permeabilized with Ղ- escin and subjected to tension measurement. NaF potentiated the concentration-response curves to Ca2＋ (decreased EC50 and increased Emax). Cumulative addition of NaF (4.0, 8.0 and 16 mM) also increased vascular tension in Ca2＋-controlled solution at pCa 7.0 or pCa 6.5, but not at pCa 8.0. NaF-induced...
400.

Mechanical Stretch-Induced Protection against Myocardial Ischemia- Reperfusion Injury Involves AMP-Activated Protein Kinase

JiaHao, Hun-SikKim, WoongChoi, TaeSunHa, Hee-YulAhn, Chan-HyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.1 1 1-9 (9 pages)

JiaHao, Hun-SikKim, WoongChoi, TaeSunHa, Hee-YulAhn, Chan-HyungKim 저
...
- 3,000원
AMP-activated protein kinase (AMPK) protects various tissues and cells from ischemic insults and is activated by many stimuli including mechanical stretch. Therefore, this study investigated if the activation of AMPK is involved in stretch-induced cardioprotection (SIC). Intraventricular balloon and aorto-caval shunt (ACS) were used to stretch rat hearts ex vivo and in vivo, respectively. Stretch preconditioning reduced myocardial infarct induced by ischemia-reperfusion (I/R) and improved...

한주간 이슈검색어