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Establishment of a canine spinal cord injury model induced by epidural balloon compression
Ji-Hey Lim, Chang-Su Jung, Ye-Eun Byeon, Wan Hee Kim, Jung-Hee Yoon, Kyung-Sun Kang, Oh-kyeong Kweon 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 13 89-94 (6 pages)
A model that provides reproducible, submaximal yet sufficient spinal cord injury is needed to allow experiments leading to development of therapeutic techniques and prediction of clinical outcome to be conducted. This study describes an experimental model for spinal cord injury that uses three different volumes of balloon inflation and durations of compression to create a controlled gradation outcome in adult dogs. Twenty-seven mongrel dogs were used for this study. A 3-french embolectomy... -
Neuropharmacological effects of deltamethrin in rats
S. Manna, D. Bhattacharyya, T. K. Mandal, S. Dey 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 7 133-136 (4 pages)
This study examined the effect of deltamethrin on some of the neuropharmacological paradigms in a rat brain such as the motor co-ordination test using a rotarod, the pentobarbitone-induced sleeping time and pentylenetetrazole (PTZ)-induced convulsion as well as the gamma aminobutyric acid (GABA) level. Albino Wistar rats were used as the experimental animals. Different neuropharmacological paradigms such as the motor co-ordination by the rotarod, pentobarbitone-induced sleeping time and the... -
Exposure to genistein does not adversely affect the reproductive system in adult male mice adapted to a soy-based commercial diet
Beom Jun Lee, Jong-Koo Kang, Eun-Yong Jung, Young Won Yun, In-Jeoung Baek, Jung-Min Yon, Yoon-Bok Lee, Heon-Soo Sohn, Jae-Yong L 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 3호 7 227-234 (8 pages)
Genistein, a soybean-originated isoflavone, is widely consumed by humans for putative beneficial health effects but its estrogenic activity may affect adversely the development of male reproductive system. Five-week-old ICR mice were purchased and fed with a soybean-based Purina Chow diet until 6 months of age. The animals were exposed by gavage to genistein (2.5 mg/kg/day) or 17β-estradiol (7.5μg/kg/day) for five weeks. Corn oil was used for the negative control. The animals were fed the... -
Norepinephrine induces MAIL mRNA expression in primary cultured hepatocytes through IL-1β released from non-parenchymal cells
Hyeon Cheol Kim , Bae Dong Jung 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2010, 제 50권 제 2호 1 79-84 (6 pages)
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Potassium Currents in Isolated Deiters' Cells of Guinea Pig
JongWooChung, EuiCholNam, WonTaeKim, JaeBoumYoum, ChaeHunLeem 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.6 10 537-546 (10 pages)
current showed slow inactivation and delayed rectification. Addition of 5 mM tetraethylammonium (TEA) further blocked the remaining current leaving a very fast inactivating transient outward current. Therefore, at least three different types of K+ current were identified in Deiters' cells, such as fast activating and fast inactivating current, fast activating slow inactivating current, and very fast inactivating transient outward current. Physiological role of them needs to be established. -
Effects of Isoflurane Anesthesia on Post-Anesthetic Sleep-Wake Architectures in Rats
Hwan-SooJang, Ji-YoungJung, Kwang-HoJang, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 7 291-297 (7 pages)
The sleep homeostatic response significantly affects the state of anesthesia. In addition, sleep recovery may occur during anesthesia, either via a natural sleep-like process to occur or via a direct restorative effect. Little is known about the effects of isoflurane anesthesia on sleep homeostasis. We investigated whether 1) isoflurane anesthesia could provide a sleep-like process, and 2) the depth of anesthesia could differently affect the post-anesthesia sleep response. Nine rats were treated... -
Acetylcholine Induces Hyperpolarization Mediated by Activation of K(Ca) Channels in Cultured Chick Myoblasts
DoyunLee, JaeheeHan, Jae-YongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 6 37-44 (8 pages)
provide direct evidence that ACh induced Ca2 influx from extracellular solution, which was dramatically increased by valinomycin-mediated hyperpolarization. In addition, ACh hyperpolarized the membrane potential from 12.5⁑3 to 31.2⁑5 mV by generating the outward current through KCa channels. These results suggest that activation of nAChR increases Ca2 influx, which activates KCa channels, thereby hyperpolarizing the membrane potential in chick myoblasts. -
Effect of Propofol on Ion Channels in Acutely Dissociated Dorsal Raphe Neuron of Sprague-Dawley Rats
Bong-JaeLee, Moo-IlKwon, Min-ChulShin, Youn-JungKim, Chang-JuKim, SoonAeKim, Ee-HwaKim, Joo-HoChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 10 189-197 (9 pages)
To investigate propofol's effects on ionic currents induced by γ-aminobutyric acid (GABA) and glycine as well as on those produced by the nicotinic acetylcholine- and glutamate-responsive channels, rat dorsal raphe neurons were acutely dissociated and the nystatin-perforated patch-clamp technique under voltage- clamp conditions was used to observe their responses to the administration of propofol. Propofol evoked ion currents in a dose-dependent manner, and propofol (104 M) was used to... -
정신분열병의 급성기 및 관해기에서의 신경인지 결손에 관한 연구
김호찬, 김철권, 박내권, 최병무 대한신경정신의학회 신경정신의학 19 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 5호 17 936-954 (19 pages)
연구목적: 본 연구는 정신분열병 환자에게서 보이는 다양한 신경인지 결손이 병의 증상 때문인지 아니면 질병 자체 의 취약성 때문인지를 알아보기 위한 것이다. 방 법: 42명의 정신분열병 환자를 대상으로 정신증적 증상이 심한 급성기와 증상이 호전된 관해기에 고난도 지속 수행검사(Continuous Performance Test)를 이용한 지속적 주의력, 정보 감지능력검사(Span Apprehension Task)를 이용한 초기 시각 정보처리능력, 위스콘신 카드분류검사(Wisconsin Card Sorting Test)를 이용한 통합능력, 숫자 주의력(Digit Span)을 이용한... -
Induction of Oscillatory Firing Activity by TTX in Rat Cerebellar Purkinje Cells
Seo, Wha-Sook 대한생리학회 대한생리학회지 88 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 1호 10 103-190 (88 pages)
Intracellular recordings were obtained from Purkinje cells in rat cerebellar slices maintained in vitro. Adding tetrodotoxin to the superfusion solution produced a typical pattern of repetitive burst firing consisting of a cluster of action potentials followed by a long hyperpolarization. TTX-induced oscillatory activity was not due to modulation of membrane potential although underlying mechanisms for maintenance of oscillatory activity were influenced by membrane voltage. The mechanism of...


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