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681.

Cilostazol Inhibits Vascular Smooth Muscle Cell Proliferation and Reactive Oxygen Species Production through Activation of AMP-activated Protein Kinase Induced by Heme Oxygenase-1

JungEunKim, JinYoungSung, Chang-HoonWoo, YoungJinKang, KwangYounLee, HeeSunKim, WooHyungKwun, HyoungChulChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.4 3 203-210 (8 pages)

JungEunKim, JinYoungSung, Chang-HoonWoo, YoungJinKang, KwangYounLee, HeeSunKim, WooHyungKwun, HyoungChulChoi 저
...
- 3,000원
Cilostazol is a selective inhibitor of phosphodiesterase 3 that increases intracellular cAMP levels and activates protein kinase A, thereby inhibiting vascular smooth muscle cell (VSMC) proliferation. We investigated whether AMP-activated protein kinase (AMPK) activation induced by heme oxygenase-1 (HO-1) is a mediator of the beneficial effects of cilostazol and whether cilostazol may prevent cell proliferation and reactive oxygen species (ROS) production by activating AMPK in VSMC. In the...
682.

Stimulatory Effects of Ginsan on the Proliferation and Viability of Mouse Spleen Cells

Eun-JuKo, Hong-GuJoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 3 133-137 (5 pages)

Eun-JuKo, Hong-GuJoo 저
...
- 1,500원
of biological activities of ginsan have been studied, the effects of ginsan on spleen cells are not fully elucidated. We investigated the effect of ginsan on the viability and proliferation of spleen cells. Using Cell Counting Kit-8Ⱂ solution and trypan blue solution, we found that ginsan significantly enhanced viability and proliferation. Multiple clusters, indicating proliferation, were observed in ginsan-treated spleen cells and, carboxyfluorescein succinimidyl ester and surface marker...
683.

Cooperation of Gβ and Gαq Protein in Contractile Response of Cat Lower Esophageal Sphincter (LES)

UyDongSohnTaiSangLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 9 349-355 (7 pages)

UyDongSohnTaiSangLee 저
...
- 3,000원
We previously shown that LES contraction depends on M3 receptors linked to PTX insensitive Gq protein and activation of PLC. This results in production of IP3, which mediates calcium release, and contraction through a CaM dependent pathway. In the esophagus ACh activates M2 receptors linked to PTX sensitive Gi3 protein, resulting in activation of PLD, presumably, production of DAG. We investigated the role of PLC isozymes which can be activated by Gq or Gβ protein on ACh-induced contraction in...
684.

Ethanol Prevents from Acetaminophen Inducible Hepatic Necrosis by Inhibiting its Metabolic Activation in Mice

Sun-MeeLee, Tai-SoonCho, Young-NamCha 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 15 261-269 (9 pages)

Sun-MeeLee, Tai-SoonCho, Young-NamCha 저
...
- 3,000원
Concomitant administration of a single acute dose of ethanol (4 g/kg) protected mice from the hepatocellular injury observed upon administration of a large dose of acetaminophen (400 mg/kg). This was evidenced by the normal histological appearances of liver sections and by the lowered serum aminotransferase activities in mice treated with ethanol and acetaminophen together. In the mice treated with acetaminophen alone, along with the hepatic necrosis, the hepatic microsomal aminopyrine...
685.

Lorazepam이 가토 혈중 주정농도에 미치는 영향에 관한 실험적 연구

尹景秀 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 1977, 제 16권 제 4호 3 340-348 (9 pages)

尹景秀 저
...
- 3,000원
686.

Medazepam 및 Cloxazolam 이 가토혈중 주정 농도에 미치는 영양에 관한 실험적 연구

高京鳳 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 1978, 제 17권 제 4호 2 343-351 (9 pages)

高京鳳 저
...
- 3,000원
687.

The Action of Ginkgo Bibloba Extract in the Isolated Rabbit Corpus Cavernosum

Chung, Woo-Sik, Choi, Young-Deuk, Park, Young-Yo, Hah, Jong-Sik 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 6 61-68 (8 pages)

Chung, Woo-Sik, Choi, Young-Deuk, Park, Young-Yo, Hah, Jong-Sik 저
...
- 3,000원
as a pharmacoerecting agent. Strips of rabbit corpus cavernosum were mounted in organ chambers to measure isometric tension. EGb began to exert an relaxing effect at 1 mg/ml in the submaximally precontracted muscle strips with phenylephrine (PHE, 5 X 10-6 M); causing concentration-dependent relaxation with maximal effect at 3 ~ 5 mg/ml. That relaxation was partially inhibited by removal of the smooth muscle endothelium or by pretreatment with a NO scavenger, pyrogallol (10-4 M) or the guanylate...
688.

수종의 알레르기 관련 약물이 흰쥐의 복강내 비만세포에서 Hyaluronidase 및 히스타민 유리에 미치는 영향

유신애(Yoo, Shin-Ae), 김구자(Kim, Ku-Ja), 하종식(Hah, Jong-Sik) 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1988, 제 22권 제 2호 9 259-272 (14 pages)

유신애(Yoo, Shin-Ae), 김구자(Kim, Ku-Ja), 하종식(Hah, Jong-Sik) 저
...
- 4,300원
689.

Multi-Homologous Recombination-Based Gene Manipulation in the Rice Pathogen Fusarium fujikuroi

한국식물병리학회 The Plant Pathology Journal 9 Pages

한국식물병리학회 The Plant Pathology Journal 2016, 32권 3호 1 173-181 (9 pages)

저
...
- 3,000원
Gene disruption by homologous recombination is widely used to investigate and analyze the function of genes in Fusarium fujikuroi, a fungus that causes bakanae disease and root rot symptoms in rice. To generate gene deletion constructs, the use of conventional cloning methods, which rely on restriction enzymes and ligases, has had limited success due to a lack of unique restriction enzyme sites. Although strategies that avoid the use of restriction enzymes have been employed to overcome this...
690.

Dual Effect of the Cubic Ag3PO4 Crystal on Pseudomonas syringae Growth and Plant Immunity

한국식물병리학회 The Plant Pathology Journal 3 Pages

한국식물병리학회 The Plant Pathology Journal 2016, 32권 2호 11 168-170 (3 pages)

저
...
- 1,500원
phosphate crystal (SPC) can also be applied to inhibit the growth of a plant-pathogenic Pseudomonas syringae bacterium. SPC pretreatment resulted in reduced in planta multiplication of P. syringae. Induced expression of a plant defense marker gene PR1 by SPC alone is suggestive of its additional plant immunity-stimulating activity. Since SPC can simultaneously inhibit P. syringae growth and induce plant defense responses, it might be used as a more effective plant disease-controlling agent.

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