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761.

Modulation of L-type Ca2+ Channel Currents by Various Protein Kinase Activators and Inhibitors in Rat Clonal Pituitary GH3 Cell Line

YoungMinBae, Hye-JungBaek, HanaCho, YungEEarm, Won-KyungHo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 4 139-146 (8 pages)

YoungMinBae, Hye-JungBaek, HanaCho, YungEEarm, Won-KyungHo 저
...
- 3,000원
L-type Ca2⁢ channels play an important role in regulating cytosolic Ca2⁢ and thereby regulating hormone secretions in neuroendocrine cells. Since hormone secretions are also regulated by various kinds of protein kinases, we investigated the role of some kinase activators and inhibitors in the regulation of the L-type Ca2⁢ channel currents in rat pituitary GH3 cells using the patch-clamp technique. Phorbol 12,13-dibutyrate (PDBu), a protein kinase C (PKC) activator, and...
762.

Effects of Prostaglandin F2α on Membrane Potentials and K+ Currents in Rabbit Middle Cerebral Arterial Cells

NariKim, JinHan, WonGueKim, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.4 5 301-309 (9 pages)

NariKim, JinHan, WonGueKim, EuiyongKim 저
...
- 3,000원
potentials and increased outward whole-cell K⁢ currents. PGF2α increased open-state probability of KCa channels without the change of the open and closed kinetics. PGF2α increased the amplitudes of KV currents with a leftward shift of activation and inactivation curves and a decrease of activation time constant. Our results suggest that the activation of KCa and KV channels, at least in part, may lead to attenuate or counteract vasoconstriction by PGF2α in middle cerebral artery.
763.

PAF Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury through Neutrophilic Oxidative Stress

YoungManLeeYoon-yubPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 5 405-414 (10 pages)

YoungManLeeYoon-yubPark 저
...
- 3,000원
The role of platelet-activating factor (PAF) was investigated in intestinal ischemia/reperfusion (I/R) induced acute lung injury associated with oxidative stress. To induce acute lung injury following intestinal I/R, superior mesenteric arteries were clamped with bulldog clamp for 60 min prior to the 120 min reperfusion in Sprague-Dawley rats. Acute lung injury by intestinal I/R was confirmed by the measurement of lung leak index and protein content in bronchoalveolar lavage (BAL) fluid. Lung...
764.

Hypothermic Preconditioning Lowers the Incidence of Hypothermic Arrest in Neonatal Rat

SungSookPark, HeungSikNa, HyunJungNam, SeungKilHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 14 231-236 (6 pages)

SungSookPark, HeungSikNa, HyunJungNam, SeungKilHong 저
...
- 3,000원
This study was performed to examine 1) Whether hypothermic cardiac arrest produces myocardial HSP72 expression; 2) And if, whether it serves to protect the heart against the subsequent hypothermic arrest. In the present study, neonatal rats were placed in an icebath to induce hypothermia. To determine whether hypothermic cardiac arrest produces myocardial HSP72, experimental animals were subjected to 10-min hypothermic insult before the extraction of the heart. The intervals between the insult...
765.

Characteristics of A1 and A2 Adenosine Receptors upon the Acetylcholine Release in the Rat Hippocampus

DoKyungKim, YoungSooLee, BongKyuChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 4 31-39 (9 pages)

DoKyungKim, YoungSooLee, BongKyuChoi 저
...
- 3,000원
766.

Spontaneous Electrical Activity in Cerebellar Purkinje Neurons of Postnatal Rats

SangChaeNam 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 2 355-366 (12 pages)

SangChaeNam 저
...
- 4,100원
after recording. Spontaneously active cells displayed two patterns of firing, repetitive and burst firings. Two thirds of dissociated Purkinje cells displayed repetitive firing and the rest of them did burst firing under same recording condition. Repetitive firing activities were maintained even after further isolation using either physical or pharmacological techniques. Neither high magnessium solution nor excitatory synaptic blockers, AP-5 and DNQX, block the spontaneous activity. These...
767.

Induction of Apoptosis by Bile Acids in HepG2 Human Hepatocellular Carcinoma Cells

JinHyenBaek, Jung-AeKim, Chang-MoKang, YongSooLee, Kyu-WonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 14 107-115 (9 pages)

JinHyenBaek, Jung-AeKim, Chang-MoKang, YongSooLee, Kyu-WonKim 저
...
- 3,000원
for the apoptosis. Intracellular Ca2+ release blockers (dantrolene and 3,4,5-trimethoxybenzoic acid-8-(diethylamino)octyl ester) inhibited decreased cell viability and DNA fragmentation induced by these bile acids. Treatment of HepG2 cells with calcium ionophore A23187 induced DNA fragmentation. These results suggest that UDCA and LCA induce apoptosis in the HepG2 cells and that the activation of intracellular Ca2+ signals may play an important role in the apoptosis induced by these bile acids.
768.

전수면박탈이 정상인의 신경인지기능에 미치는 영향

이헌정, 김인, 서광윤 대한신경정신의학회 신경정신의학 11 Pages

대한신경정신의학회 신경정신의학 1999, 제 38권 제 3호 3 480-490 (11 pages)

이헌정, 김인, 서광윤 저
...
- 4,000원
연구목적： 본 연구는 전산화 신경인지기능 검사인 Vienna Test System과 사건관련유발전위인 P300을 이용하여 수면 박탈이 인간의 신경인지 및 정신생리적 기능에 미치는 효과를 알아보고자 하였으며, 또한 수면박탈 후에 P300 의 변화가 인지 과정의 어떤 면과 관련되는 지를 살펴보고자 시도되었다. 방 법： 고려대학교 의과대학 재학생 중 건강한 자원자 30명을 대상으로 하여 총 38시간의 수면박탈을 시행하였고 2 일간 아침, 저녁으로 총 네차례 Vienna Test System와 P300을 실시하였다. 결 과： Vienna Test System의 소검사 중...
769.

대뇌 피질 신경 세포 일차 배양에서 6-hydroxydopamine에 의한 신경세포사멸의 특성

정재훈, 강효정, 손성향, 정영기, 곽병주, 노재성 대한신경정신의학회 신경정신의학 10 Pages

대한신경정신의학회 신경정신의학 2000, 제 39권 제 3호 17 656-665 (10 pages)

정재훈, 강효정, 손성향, 정영기, 곽병주, 노재성 저
...
- 3,000원
연구목적： 본 연구는 생쥐 태자 대뇌 피질 세포 일차 배양에서 파킨슨씨병의 동물 모델을 만드는데 사용되는 신경독 성 물질인 6-hydroxydopamine(6-OHDA)에 의한 신경세포 사멸의 특성을 관찰한 것이다. 방 법： 생쥐태자의 신경세포를 배양하여 6-OHDA를 처리하고 이와 더불어 여러가지 신경세포 사멸에 영향을 주 는 물질을 투여하여 신경세포의 사멸을 정량적으로 분석하고 형태학적 분석을 전자현미경을 통하여 관찰하 였다 결 과： 배양한 신경세포에 6-OHDA를 처리하면 투여 양에 비례하여 신경세포의 사멸이 증가하며 50μM 6-...
770.

알코올 사용장애의 뇌영상 소견

이병욱 대한신경정신의학회 신경정신의학 5 Pages

대한신경정신의학회 신경정신의학 2004, 제 43권 제 6호 3 633-637 (5 pages)

이병욱 저
...
- 1,500원

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