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총 195건 검색
본문검색 결과만 보기
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Two Dinucleotide Repeat Polymorphisms (AC/TG and GT/CA) in the 5' Upstream Region of the Mouse Tryptophan Hydroxylase Gene
Sung-VinYim, Sung-GilChi, Sung-HyunChung, Hee-JaeLee, Mi-JaKim, Seung-JoonPark, Jee-ChangJung, Joo-HoChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 6 501-505 (5 pages)
Tryptophan hydroxylase (TPH), the rate-limiting enzyme in serotonin biosynthesis, is primarily expressed in serotonergic neurons of the raphe nuclei. Simple tandem repeat polymorphisms, typically one to four nucleotides long, are tandemly repeated several times and often characterized by many alleles. To identify the presence of polymorphic repeats, we sequenced the 5'-upstream region of the mouse TPH gene. For the detection of any allelic variants, polymerase chain reaction, nonisotopic... -
Increased Activity of Large Conductance Ca2+-Activated K+ Channels in Negatively-Charged Lipid Membranes
JinBongParkPanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 15 529-539 (11 pages)
The effects of membrane surface charge originated from lipid head groups on ion channels were tested by analyzing the activity of single large conductance Ca2-activated K (maxi K) channel from rat skeletal muscle. The conductances and open-state probability (Po) of single maxi K channels were compared in three types of planar lipid bilayers formed from a neutral phosphatidylethanolamine (PE) or two negatively-charged phospholipids, phosphatidylserine (PS) and phosphatidylinositol... -
Effect of t-butylhydroperoxide on Na+-dependent Glutamate Uptake in Rabbit Brain Synaptosome
HyunJeLeeYongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 3 367-376 (10 pages)
The effect of an organic peroxide, t-butylhydroperoxide (t-BHP), on glutamate uptake was studied in synaptosomes prepared from cerebral cortex. t-BHP inhibited the Na+-dependent glutamate uptake with no change in the Na+-independent uptake. This effect of t-BHP was not altered by addition of Ca2+ channel blockers (verapamil, diltiazem and nifedipine) or PLA2 inhibitors (dibucaine, butacaine and quinacrine). However, the effect was prevented by iron chelators (deferoxamine and phenanthroline)... -
정신분열병 및 양극성 장애에서 종양괴사인자 - 알파 유전자 다형성의 연합 연구
김종우, 전태연, 배치운, 이경욱 대한신경정신의학회 신경정신의학 6 Pages
대한신경정신의학회 신경정신의학 2003, 제 42권 제 5호 4 559-564 (6 pages)
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왜 다양한 항우울제가 필요한가?
윤호경, 김용구 대한신경정신의학회 신경정신의학 11 Pages
대한신경정신의학회 신경정신의학 2008, 제 47권 제 1호 2 11-21 (11 pages)
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精神分裂症의 側頭葉 病理
대한신경정신의학회 신경정신의학 1995, 제 34권 제 5호 12 1361-1371 (11 pages)
