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71.

Gender-Related Differences in a Process of the Age-Dependent Alterations of the Elements in Monkey Sino-Atrial Node

HiroyasuSatoh, SetsukoTohno, TakeshiMinami, TakaoOishi, MotoharuHayashi, YoshiyukiTohno 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 1 249-256 (8 pages)

HiroyasuSatoh, SetsukoTohno, TakeshiMinami, TakaoOishi, MotoharuHayashi, YoshiyukiTohno 저
...
- 3,000원
Gender differences in the trace elements of monkey sino-atrial (SA) node were investigated in a process of age-dependent alterations. Sixty hearts from Japanese and rhesus monkeys (30 male and 30 female) used were aged ranging from 1-day- to 30-year-old. The elements were analyzed using an inductively coupled plasma-atomic emission spectrometer (ICP-AES). Advancing age decreased all the trace elements. Ca, P, S and Mg significantly decreased. The correlation coefficients of Ca and P were...
72.

Multiple Residues in the P-Region and M2 of Murine Kir 2.1 Regulate Blockage by External Ba2＋

YoungMeeLee, GarethA.Thompson, IanAshmole, MarkLeyl, InsukSo, PeterR.Stanfield 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.1 10 61-69 (9 pages)

YoungMeeLee, GarethA.Thompson, IanAshmole, MarkLeyl, InsukSo, PeterR.Stanfield 저
...
- 3,000원
We have examined the effects of certain mutations of the selectivity filter and of the membrane helix M2 on Ba2＋ blockage of the inward rectifier potassium channel, Kir 2.1. We expressed mutant and wild type murine Kir 2.1 in Chinese hamster ovary (CHO) cells and used the whole cell patch-clamp technique to record K＋ currents in the absence and presence of externally applied Ba2＋. Wild type Kir2.1 was blocked by externally applied Ba2＋ in a voltage and concentration dependent manner. Mutants...
73.

Mechanisms of Selective Antimicrobial Activity of Gaegurin 4

HeejeongKim, ByeongJaeLee, MunHanLee, SeongGeunHong, PanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.1 7 39-48 (10 pages)

HeejeongKim, ByeongJaeLee, MunHanLee, SeongGeunHong, PanDongRyu 저
...
- 3,000원
Gaegurin 4 (GGN4), an antimicrobial peptide isolated from a Korean frog, is five times more potent against Gram-positive than Gram-negative bacteria, but has little hemolytic activity. To understand the mechanism of such cell selectivity, we examined GGN4-induced K＋ efflux from target cells, and membrane conductances in planar lipid bilayers. The K＋ efflux from Gram-positive M. luteus (2.5</SUP>Ռg/ml) was faster and larger than that from Gram-negative E. coli (75Ռg/ml), while...
74.

Pre-ischemic Treatment with Ampicillin Reduces Neuronal Damage in the Mouse Hippocampus and Neostriatum after Transient Forebrain Ischemia

Kyung-EonLee, Seul-KiKim, Kyung-OkCho, SeongYunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.6 1 287-292 (6 pages)

Kyung-EonLee, Seul-KiKim, Kyung-OkCho, SeongYunKim 저
...
- 3,000원
Ampicillin, a Ղ-lactam antibiotic, has been reported to induce astrocytic glutamate transporter-1 which plays a crucial role in protecting neurons against glutamate excitotoxicity. We investigated the effect of ampicillin on neuronal damage in the mouse hippocampus and neostriatum following transient global forebrain ischemia. Male C57BL/6 mice were anesthetized with halothane and subjected to bilateral occlusion of the common carotid artery for 40 min. Ampicillin was administered...
75.

Effects of Repeated Citalopram Treatments on Chronic Mild Stress- Induced Growth Associated Protein-43 mRNA Expression in Rat Hippocampus

Sang-HaPark, Song-hyenChoi, JiminLee, SeungwooKang, You-ChanShin, Hyun-JuKim, HyunJungKim, SeungKeonShin, Min-SooLee, Kyung-HoShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.3 5 117-124 (8 pages)

Sang-HaPark, Song-hyenChoi, JiminLee, SeungwooKang, You-ChanShin, Hyun-JuKim, HyunJungKim, SeungKeonShin, Min-SooLee, Kyung-HoShin 저
...
- 3,000원
Although growth associated protein-43 (GAP-43) is known to play a significant role in the regulation of axonal growth and the formation of new neuronal connections in the hippocampus, there is only a few studies on the effects of acute stress on GAP-43 mRNA expression in the hippocampus. Moreover, the effects of repeated citalopram treatment on chronic mild stress (CMS)-induced changes in GAP-43 mRNA expression in the hippocampus have not been explored before. To explore this question, male rats...
76.

Effects of R. Glutinosa and E. Senticosus on Postmenopausal Osteoporosis

SooYeonOh, DipendraKumarAryal, Yoon-GyoonKim, , Hyung-GunKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 7 121-127 (7 pages)

SooYeonOh, DipendraKumarAryal, Yoon-GyoonKim, , Hyung-GunKim, 저
...
- 3,000원
In this study, we investigated the therapeutic effects of a novel formulation of low-dose calcium and vitamin D3, blended with Rehmannia glutinosa Libosch and Eleutherococcus senticosus Max (RE⁢), in postmenopausal women. The controls were given either a placebo or high dose calcium and vitamin D3 (Ca⁢D). Bone mineral density (BMD) in the L2-3 lumber spines and femur regions was assessed, and serum osteocalcin, bone-specific alkaline phosphatase (BALP), and cross-linked N-telopeptide...
77.

NADPH Oxidase and Mitochondrial ROS are Involved in the TNF-α-induced Vascular Cell Adhesion Molecule-1 and Monocyte Adhesion in Cultured Endothelial Cells

JaeHyeonYu, CukSeongKim, DaeGoonYoo, YunJeongSong, HeeKyoungJoo, GunKang, JiYoonJo, JinBongPark, ByeongHwaJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.4 9 217-221 (5 pages)

JaeHyeonYu, CukSeongKim, DaeGoonYoo, YunJeongSong, HeeKyoungJoo, GunKang, JiYoonJo, JinBongPark, ByeongHwaJeon 저
...
- 1,500원
Atherosclerosis is considered as a chronic inflammatory process. However, the nature of the oxidant signaling that regulates monocyte adhesion and its underlying mechanism is poorly understood. We investigated the role of reactive oxygen species on the vascular cell adhesion molecule-1 (VCAM-1) and monocyte adhesion in the cultured endothelial cells. TNF-α at a range of 1~30 ng/ml induced VCAM-1 expression dose-dependently. BCECF-AM-labeled U937 cells firmly adhered on the surface of...
78.

Protective Effect of Defibrotide on Splanchnic Injury following Ischemia and Reperfusion in Rats

SooRanChoi, JiHoonJeong, JinHoSong, YongKyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.2 5 85-94 (10 pages)

SooRanChoi, JiHoonJeong, JinHoSong, YongKyooShin 저
...
- 3,000원
A splanchic artery occlusion for 90 min followed by reperfusion of the mesenteric circulation resulted in a severe form of circulatory shock, characterized by endothelial dysfunction, severe hypotension, marked intestinal tissue injury, and a high mortality rate. The effect of defibrotide, a complex of single-stranded polydeoxyribonucleotides having antithrombotic effect, was investigated in a model of splanchnic artery occlusion (SAO) shock in urethane anesthetized rats. Occlusion of the...
79.

Secondary Fish-Odor Syndrome Can be Acquired by Nitric Oxide-mediated Impairment of Flavin-containing Monooxygenase in Hepatitis B Virus-Infected Patients

Hyeon-GyuYi, Jung-NamLee, SeungDukRyu, Ju-HeeKang, Young-NamCha, Chang-ShinPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.4 7 213-218 (6 pages)

Hyeon-GyuYi, Jung-NamLee, SeungDukRyu, Ju-HeeKang, Young-NamCha, Chang-ShinPark 저
...
- 3,000원
Primary fish-odor syndrome (FOS) is a genetic disorder caused by defective flavin-containing monooxygenase 3 gene (FMO3) with deficient N-oxidation of trimethylamine (TMA), causing trimethylaminuria (TMAU). By contrast, secondary FOS can be acquired by decreased FMO activities in patients with chronic liver diseases, but the underlying mechanisms are unknown. In the present study, we examined plasma NOx concentrations and viral DNA contents as well as in vivo FMO activities and their...
80.

Heterogeneity of the SR-dependent Inward Na+-Ca2+ Exchange Current in the Heavily Ca2+-buffered Rat Ventricular Myocytes

Kyung-BongYoon, Sung-WanAhn, ChangMannKo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.2 6 101-110 (10 pages)

Kyung-BongYoon, Sung-WanAhn, ChangMannKo 저
...
- 3,000원
Voltage-sensitive release mechanism was pharmacologically dissected from the Ca2⁢-induced Ca2⁢ release in the SR Ca2⁢ release in the rat ventricular myocytes patch-clamped in a whole-cell mode. SR Ca2⁢ release process was monitored by using forward-mode Na⁢-Ca2⁢ exchange after restriction of the interactions between Ca2⁢ from SR and Na⁢-Ca2⁢ exchange within micro-domains with heavy cytosolic Ca2⁢ buffering with 10 mM BAPTA. During...

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