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전체 선택해제
총 1,041건 검색
본문검색 결과만 보기
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Selective Cytotoxicity of a Novel Platinum(II) Coordination Complex on Human Bladder Cancer Cell Lines and Normal Kidney Cells
Jee-ChangJung, Joo-HoChung, Sung-GooChang, Young-SooRho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.2 11 159-167 (9 pages)
cells. PC has demonstrated high levels of cytotoxicity against T-24 and J-82 cells. The cytotoxicity of PC against rabbit proximal renal tubular cells, human renal cortical cells and human renal cortical tissues, determined using the MTT assaying technique, the [3H]-thymidine uptake and glucose consumption tests, was found to be quite less than those of cisplatin. Based on these results, this novel platinum(II) coordination complex appears to be better for improving antitumor activities with low... -
Glycochenodeoxycholic Acid Induces Cell Death in Primary Cultured Rat Hepatocyte Apoptosis and Necrosis
SangHuiChu, WolMiPark, KyungEunLee, YoungSookPae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 4 565-570 (6 pages)
can be a mechanism of cell death during cholestatic liver diseases instead of necrosis. To determine the pattern of hepatocellular toxicity induced by bile acid, we incubated primary cultured rat hepatocytes with a hydrophobic bile acid, Glycochenodeoxycholate (GCDC), up to 5 hours. After 5 hours incubation with 400 μM GCDC, lactate dehydrogenase released significantly. Cell viability, quantitated in propidium iodide stained cells concomitant with fluoresceindiacetate was decreased time- and... -
Selective Cytotoxicity of a Novel Platinum (II) Coordination Complex on Human Gastric Cancer Cell Lines and Normal Kidney Cells
Jee-ChangJung, Young-KyuKim, Sung-VinYim, Seung-JoonPark, Joo-HoChung, Sung-GooChang, Kyung-TaeLee, Young-SooRho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 6 283-291 (9 pages)
on various MKN-45 human gastric adenocarcinoma cell-lines and normal primary cultured kidney cells. The new platinum complex demonstrated high efficacy in the cytotoxicity on MKN-45 cell-lines as well as adriamycin-resistant (MKN-45/ADR) and cisplatin-resistant (MKN-45/CDDP) cells. The cytotoxicities of PC were found quite less than those of cisplatin in rabbit proximal renal tubular cells, human renal cortical cells and human renal cortical tissues using MTT assay, [3H]-thymidine uptake and... -
Calcium Modulates Excitatory Amino Acid (EAA)- and Substance P-induced Rat Dorsal Horn Cell Responses
HongKeeShin, SokHanKang, InDukChung, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 5 35-45 (11 pages)
rat. All the LT cells tested responded to kainate, whereas about 55% of low threshold (LT) cells responded to iontophoretically applied NMDA. NMDA and kainate excited almost all wide dynamic range (WDR) cells. These NMDA- and kainate-induced WDR cell responses were augmented by iontophoretically applied EGTA, but suppressed by Ca2, Mn2, verapamil and ω-conotoxin EVTA, effect of verapamil being more prominent and well sustained. Ca2 and Mn2 antagonized the augmenting... -
The Inhibitory Mechanism of Aloe Glycoprotein (NY945) on the Mediator Release in the Guinea Pig Lung Mast Cell Activated with Antigen-Antibody Complexes
JaiYoulRo, ByungChulLee, MyungHeeChung, SeungKiLee, ChungKiSung, KyungHwanKim, YoungInPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 15 119-131 (13 pages)
mediator re1eases caused by mast cell activation， and a1so aimed to assess the effects of NY945 on the mechanism of mediator re1eases in the mast cell activation. We partially purified mast cell from guinea pig 1ung tissues by using the enzyme digestion， the rough and the discontinuous density percoll gradient method. Mast cells were sensitized with IgG1 (anti-OA) and challenged with ova1bumin. Histamine was assayed by fluorometric ana1yzer， 1eukotrienes by radioimmunoassay. The phospholipase... -
Transepithelial Transport of Organic Cation and Its Inhibition by Sulfhydryl and Carboxyl Reagents in Opossum Kidney Cell Monolayer
Woo, Jae-Suk, Oh, Se-Ok, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 6 53-62 (10 pages)
acid (PCMB) and ρ-chloro-mercuribenzene sulfonate (PCMBS) and carboxyl reagents such as N,N -dicyclohexylcarbodiimidem (DCCD) and N-ethoxy-carbonyl-2-ethoxy-1,2-dihydro-quinoline(EEDQ) inhibited the TEA transport at both the basolateral and apical membranes of the OK cell monolayer. These results suggest that OK cell monolayers possess a vectorial transport system for organic cations which is similar to that for organic cation secretion in the renal proximal tubule. -
Physiology of Man under High Pressure
Hong Suk-Ki 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1988, 제 22권 제 2호 1 153-162 (10 pages)
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Enhanced Tolerance of Chinese Cabbage Seedlings Mediated by Bacillus aryabhattai H26-2 and B. siamensis H30-3 against High Temperature Stress and Fungal Infections
Young Hee Lee, Su Jeong Jang, Joon-Hee Han, Jin Su Bae, Hyun-suk Shin, Hee Jin Park, Mee Kyung Sang, Song Hee Han, Kyoung Su Kim, Sang-W 한국식물병리학회 The Plant Pathology Journal 12 Pages
한국식물병리학회 The Plant Pathology Journal 2018, 34권 6호 10 555-566 (12 pages)
Two rhizobacteria Bacillus aryabhattai H26-2 and B. siamensis H30-3 were evaluated whether they are involved in stress tolerance against drought and high temperature as well as fungal infections in Chinese cabbage plants. Chinese cabbage seedlings cv. Ryeokgwang (spring cultivar) has shown better growth compared to cv. Buram-3-ho (autumn cultivar) under high temperature conditions in a greenhouse, whilst there was no difference in drought stress tolerance of the two cultivars. In vitro growth of...
