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801.

Screening of Genetic Polymorphisms of CYP3A4 and CYP3A5 Genes

JinSolLee, HyunSubCheong, LyoungHyoKim, JiOnKim, DooWonSeo, YoungHoonKim, MyeonWooChung, SoonYoungHan, HyoungDooShin, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.6 1 479-484 (6 pages)

JinSolLee, HyunSubCheong, LyoungHyoKim, JiOnKim, DooWonSeo, YoungHoonKim, MyeonWooChung, SoonYoungHan, HyoungDooShin, 저
...
- 3,000원
Given the CYP3A4 and CYP3A5’s impact on the efficacy of drugs, the genetic backgrounds of individuals and populations are regarded as an important factor to be considered in the prescription of personalized medicine. However, genetic studies with Korean population are relatively scarce compared to those with other populations. In this study, we aimed to identify CYP3A4/5 polymorphisms and compare the genotype distributions among five ethnicities. To identify CYP3A4/5 SNPs, we first performed...
802.

2-(4-Hydroxyphenyl)-5-(3-Hydroxypropenyl)-7-Methoxybenzofuran, a Novel Ailanthoidol Derivative, Exerts Anti-Inflammatory Effect through Downregulation of Mitogen-Activated Protein Kinase in Lipopolysaccharide-Treated RAW 264.7 Cells

HyeonJinKim, Jong-GabJun, Jin-KyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.3 6 217-222 (6 pages)

HyeonJinKim, Jong-GabJun, Jin-KyungKim 저
...
- 3,000원
We reported that ailanthoidol, a neolignan from Zanthoxylum ailanthoides and Salvia miltiorrhiza Bunge, inhibited inflammatory reactions by macrophages and protected mice from endotoxin shock. We examined the anti-inflammatory activity of six synthetic ailanthoidol derivatives (compounds 1-6). Among them, compound 4, 2-(4-hydroxyphenyl)-5-(3-hydroxypropenyl)-7-methoxybenzofuran, had the lowest IC50 value concerning nitric oxide (NO) release from lipopolysaccharide (LPS)-stimulated RAW264.7...
803.

Effect of Cholera Toxin Administered Supraspinally or Spinally on the Blood Glucose Level in Pain and D-Glucose Fed Animal Models

Yun-BeomSim, Soo-HyunPark, Yu-JungKang, Sung-SuKim, Chea-HaKim, Su-JinKim, Jun-SubJung, Ohk-HyunRyu, Moon-GiChoi, Seong-SooChoi, Hong-WonS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.2 8 163-167 (5 pages)

Yun-BeomSim, Soo-HyunPark, Yu-JungKang, Sung-SuKim, Chea-HaKim, Su-JinKim, Jun-SubJung, Ohk-HyunRyu, Moon-GiChoi, Seong-SooChoi, Hong-WonS 저
...
- 1,500원
In the present study, the effect of intrathecal (i.t.) or intracerebroventricular (i.c.v.) administration with cholera toxin (CTX) on the blood glucose level was examined in ICR mice. The i.t. treatment with CTX alone for 24 h dose-dependently increased the blood glucose level. However, i.c.v. treatment with CTX for 24 h did not affect the blood glucose level. When mice were orally fed with D-glucose (2 g/kg), the blood glucose level reached to a maximum level at 30 min and almost returned to...
804.

Functional Expression of P2Y Receptors in WERI-Rb1 Retinoblastoma Cells

Na-HyunKim, Kyu-SangPark, JoonHyungSohn, Byung-IlYeh, ChangMannKo, InDeokKong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.1 9 61-65 (5 pages)

Na-HyunKim, Kyu-SangPark, JoonHyungSohn, Byung-IlYeh, ChangMannKo, InDeokKong 저
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- 1,500원
P2Y receptors are metabotropic G-protein-coupled receptors, which are involved in many important biologic functions in the central nervous system including retina. Subtypes of P2Y receptors in retinal tissue vary according to the species and the cell types. We examined the molecular and pharmacologic profiles of P2Y purinoceptors in retinoblastoma cell, which has not been identified yet. To achieve this goal, we used Ca2＋ imaging technique and western blot analysis in WERI-Rb-1 cell, a human...
805.

The Effect of Extracellular Glutamate Release on Repetitive Transient Ischemic Injury in Global Ischemia Model

GiJaLee, SeokKeunChoi, YunHyeEo, SungWookKang, SamjinChoi, JeongHoonPark, JiEunLim, KyungWonHong, HyunSeokJin, BermSeokOh, HunKukPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.1 4 23-26 (4 pages)

GiJaLee, SeokKeunChoi, YunHyeEo, SungWookKang, SamjinChoi, JeongHoonPark, JiEunLim, KyungWonHong, HyunSeokJin, BermSeokOh, HunKukPark 저
...
- 1,500원
During operations, neurosurgeons usually perform multiple temporary occlusions of parental artery, possibly resulting in the neuronal damage. It is generally thought that neuronal damage by cerebral ischemia is associated with extracellular concentrations of the excitatory amino acids. In this study, we measured the dynamics of extracellular glutamate release in 11 vessel occlusion (VO) model to compare between single occlusion and repeated transient occlusions within short interval. Changes in...
806.

Combination of Electroconvulsive Therapy and Clozapine in Treatment-Resistant Schizophrenia

Jung Hyun Kim, Tak Youn, Jun Gwon Choi, Seong Hoon Jeong, Hee Yeon Jung, Yong Sik Kim, In Won Chung 대한신경정신의학회 Psychiatry Investigation 7 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 13 829-835 (7 pages)

Jung Hyun Kim, Tak Youn, Jun Gwon Choi, Seong Hoon Jeong, Hee Yeon Jung, Yong Sik Kim, In Won Chung 저
...
- 3,000원
The clinical remission defined as 20% PANSS reduction criteria was achieved at 42.9%. The subscale factors were significantly reduced, among which the negative symptom was the least. There was no difference in demographic and clinical information between patients receiving and not receiving maintenance ECT, and not all patients seemed to need maintenance ECT if clozapine is continued. Conclusion_Combination of ECT and clozapine in patients with clozapine-resistant schizophrenia resulted in a...
807.

Physical Activity of Patients with Chronic Schizophrenia and Related Clinical Factors

Sook-Hyun Lee, Gyurin Kim, Chul-Eung Kim, Seunghyong Ryu 대한신경정신의학회 Psychiatry Investigation 7 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 10 811-817 (7 pages)

Sook-Hyun Lee, Gyurin Kim, Chul-Eung Kim, Seunghyong Ryu 저
...
- 3,000원
Objective_This study aimed to investigate clinical factors contributing to the low physical activity (PA) of patients with chronic schizophrenia. Methods_PA was measured in 50 outpatients with chronic schizophrenia using the International Physical Activity Questionnaire Short Form (IPAQ-SF). Psychopathology, psychosocial functioning, and extrapyramidal symptoms were assessed using the 18 item-Brief Psychiatric Rating Scale (BPRS-18), Global Assessment of Functioning (GAF), and Drug-Induced...
808.

특발성 경련 환아에 대한 부모와 일반인의 태도 비교

김붕년, 조수철, 홍강의 대한신경정신의학회 신경정신의학 13 Pages

대한신경정신의학회 신경정신의학 2001, 제 40권 제 1호 4 37-49 (13 pages)

김붕년, 조수철, 홍강의 저
...
- 4,200원
연구목적： 경련성 환아에 대한 사회적 인식과 편견을 파악하기 위해 본 연구를 시행하였다. 방 법： 특발성 경련 질환으로 진단받고 12개월이상 치료중인 58명의 환아 부모군과 30명의 건강한 아동을 둔 부 모군을 대상으로 하여,“경련 질환에 대한 인식조사 설문”를 통해 환아 부모군과 일반인군(대조군)의 인식 차이를 알아보았다. 결 과： 환아 부모군의 인식 태도를 알아보면 다음과 같다. 첫째, 경련으로 인한 신체적 손상에 대해 지나치게 걱 정하는 태도를 보여주어 25%의 부모군은 한번의 경련으로도 환아가 사망할 수 있다고...
809.

혈관성 우울증

김도훈 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 2002, 제 41권 제 4호 5 603-611 (9 pages)

김도훈 저
...
- 3,000원
혈관성 우울증의 개념은 고혈압, 당뇨병, 관상동맥 질환 그리고 뇌졸중 환자에서 높은 우울증 발생율 과 노인우울증 환자에서 흔하게 silent cerebral infarct과 백질 고음영(white matter hyperintensities) 이 발견된다는 사실에 의해 지지된다. 혈관성 우울증의 임상적 가치는 우울증 발생의 원인, 임상양상, 치료방법, 예후등이 상이한 우울증의 중요한 subtype이 될 수 있다는 점이다. 또한 혈관성 우울증의 개념은 뇌혈관 질환의 위험 요인을 경감시킴으로서 노인 우울증등과 같은 뇌혈관 질환과 관련된 우울 증의 일차 및 이차...
810.

Ziprasidone의 자연적 임상경험에 대한 후향적 조사 연구：3개 대학병원의 경험

이승재, 강도형, 홍경수, 주연호, 김남식, 권준수 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 2007, 제 46권 제 3호 3 214-222 (9 pages)

이승재, 강도형, 홍경수, 주연호, 김남식, 권준수 저
...
- 3,000원

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