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881.

The Effect of Carbon Monoxide on L-type Calcium Channel Currents in Human Intestinal Smooth Muscle Cells

InjaLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 10 357-362 (6 pages)

InjaLim 저
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- 3,000원
this study was to determine the effects of exogenous CO on L-type calcium channel currents of human jejunal circular smooth muscle cells. Cells were voltage clamped with 10 mM barium (Ba2⁢) as the charge carrier, and CO was directly applied into the bath to avoid perfusion induced effects on the recorded currents. 0.2% CO was increased barium current (IBa) by 15⁑2% (mean⁑S.E., p＜0.01, n=11) in the cells. To determine if the effects of CO on barium current were mediated through...
882.

Stretch-activated K+ Channels in Rat Atrial Myocytes

JaeBoumYoum 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 8 341-318 (8 pages)

JaeBoumYoum 저
...
- 3,000원
to mediate these events. In this study, cell-attached and inside-out excised-patch clamp methods were used to identify stretch-activated cation channels in adult rat atrial myocytes. Channel openings were increased in cell-attached configuration when negative pressure was applied to the pipette, and also in inside-out excised patches by negative pressure. The channel was not permeable to Cl⁣, Na⁢ and Cs⁢, but selectively permeable to K⁢, and the degree of activation was...
883.

Electrophysiological and Morphological Classification of Inhibitory Interneurons in Layer II/III of the Rat Visual Cortex

Duck-JooRhie, HoYoungKang, GyeongRyulRyu, Myung-JunKim, ShinHeeYoon, SangJuneHahn, DoSikMin, Yang-HyeokJo, Myung-SukKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 5 317-323 (7 pages)

Duck-JooRhie, HoYoungKang, GyeongRyulRyu, Myung-JunKim, ShinHeeYoon, SangJuneHahn, DoSikMin, Yang-HyeokJo, Myung-SukKim 저
...
- 3,000원
peak-to-trough time (P-T time) of the afterhyperpolarization (＜4 msec). In addition to the shorter AP width, RSNP had the higher input resistance (＞200 MΩ) and the shorter P-T time (＜20 msec) than those of regular spiking pyramidal neurons. Confocal reconstruction of recorded cells revealed characteristic morphology of each subtype of inhibitory interneurons. Thus, our results provide at least four subtypes of inhibitory interneurons in layer II/III of the rat primary visual cortex and a...
884.

SM709, Ingredient of Antimelanogenic Bamboo Extract, Blocks Endothelin-1-induced [Ca2+]i Increase in Human Melanocytes

Shin-HeeKim, Ki-MuLee, HyoShinKim, GyuSeungLee, ByeongHwaJeon, KwangJinKimJinBongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 4 311-316 (6 pages)

Shin-HeeKim, Ki-MuLee, HyoShinKim, GyuSeungLee, ByeongHwaJeon, KwangJinKimJinBongPark 저
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- 3,000원
in a concentration- and time-dependent manner, although another ingredients SM707 and SM708 had no effect on ET-1-induced [Ca2⁢]i increase in human melanocytes. SM709 (100μM), however, did not affect [Ca2⁢]i increase induced by thapsigargin and caffeine, suggesting that SM709 has no effect on the Ca2⁢ store in melanocytes. Furthermore, SM709 did not affect [Ca2⁢]i increase induced by LPA or ATP, known as G protein-mediated PLC activators like ET-1. Taken together, it is...
885.

Inhibitory Modulation of 5-Hydroxytryptamine on Corticostriatal Synaptic Transmission in Rat Brain Slice

SeJoonChoi, WonSoonChung, Ki-JungKim, Ki-WugSung, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 1 295-301 (7 pages)

SeJoonChoi, WonSoonChung, Ki-JungKim, Ki-WugSung, 저
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- 3,000원
Striatum plays a crucial role in the movement control and habitual learning. It receives an information from wide area of cerebral cortex as well as an extensive serotonergic (5-hydroxytryptamine, 5-HT) input from raphe nuclei. In the present study, the effects of 5-HT to modulate synaptic transmission were studied in the rat corticostriatal brain slice using in vitro extracellular recording technique. Synaptic responses were evoked by stimulation of cortical glutamatergic inputs on the corpus...
886.

Prevention of Diabetes Using Adenoviral Mediated Hepatocyte Growth Factor Gene Transfer in Mice

Hye-JeongLee, Hyun-JeongKim, Mee-SookRoh, Jae-IkLee, Sung-WonLee, Dong-SikJung, Duk-KyuKim, Mi-KyoungPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.5 3 261-266 (6 pages)

Hye-JeongLee, Hyun-JeongKim, Mee-SookRoh, Jae-IkLee, Sung-WonLee, Dong-SikJung, Duk-KyuKim, Mi-KyoungPark 저
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- 3,000원
T cells-mediated destruction of the insulin-producing beta cells in the Langerhans pancreatic islets. Hepatocyte growth factor (HGF) is a potent mitogen and a promoter of proliferation of insulin producing beta cells of pancreatic islets. To study the role of HGF via viral vector in the development of streptozotocin (STZ)-induced diabetes in mice, we have developed an adenoviral vector genetically engineered to carry the gene for human HGF (hHGF) and evaluate the change of blood glucose, insulin...
887.

A Simple and Sensitive Assay for Cefepime in Human Plasma Using High Performance Liquid Chromatography

Young-SunKim, Dong-SeokYim, Dong-GunLee, Sang-BokLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 9 247-250 (4 pages)

Young-SunKim, Dong-SeokYim, Dong-GunLee, Sang-BokLee 저
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- 1,500원
mm; particle size 5μm, Waters) and the column was eluted with methanol and 0.01 M dihydrogen phosphate at pH 3.0 (15：85 v：v) as a mobile phase at a flow rate of 0.7 mL/min. Linearity was confirmed for the range 0.25 to 200μL/mL and the limit of quantitation was 0.25μL/mL. The retention times were 10.2 min and 13.4 min for cefepime and cefadroxil, respectively. This method was successfully applied to a pharmacokinetic study of cefepime in plasma from bone marrow transplant patients.
888.

Salicylate Regulates Cyclooxygenase-2 Expression through ERK and Subsequent NF-κB Activation in Osteoblasts

Han-JungChae, Jun-KiLee, Joung-OukByun, Soo-WanChae, Hyung-RyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 8 239-246 (8 pages)

Han-JungChae, Jun-KiLee, Joung-OukByun, Soo-WanChae, Hyung-RyongKim 저
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- 3,000원
in combined cytokines-treated cells, and also inhibited the activation of ERK, IKK and NF-κB in MC3T3E1 osteoblasts. In addition, TNF-α/IFN-γ stimulated ROS release in the osteoblasts. However, salicylate had no obvious effect on ROS release in DCFDA assay. The results showed that salicylate inhibited the activation of ERK and IKK, IκB degradation and NF-κB activation independent of ROS release and suggested that salicylate exerts its anti-inflammatory action in part through inhibition of...
889.

Enhancement of ATP-induced Currents by Phospholipase D1 Overexpressed in PC12 Cells

JinBongPark, YoungRaeKim, ByeongHwaJeon, Seung-KielPark, Sae-OckOh, YoungGeunKim, SangDoLee, KwangJinKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 6 223-229 (7 pages)

JinBongPark, YoungRaeKim, ByeongHwaJeon, Seung-KielPark, Sae-OckOh, YoungGeunKim, SangDoLee, KwangJinKim 저
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- 3,000원
were also larger in PLD1-PC12 cells than in control cells. However, the difference between the two groups of cells disappeared in Ca2⁢-free external solution, where ATP did not activate PLD. Finally, ATP-induced 45Ca uptakes were also larger in PLD1-PC12 cells than in control cells. These results suggest that PLD enhances ATP-induced Ca2⁢ influx via Ca2⁢ permeable nonselective cation channels and increases subsequent Ca2⁢-activated K⁢ currents in PC12 cells.
890.

Fuctional Relationship between Rate of Fatty Acid Oxidation and Carnitine Palmitoyl Transferase I Activity in Various Rat Tissues

Yu-LeeCho, Kyung-OhDo, Tae-DongKwon, Eung-ChanJang, Keun-MiLee, Suck-KangLee, Jong-YeonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 3 207-210 (4 pages)

Yu-LeeCho, Kyung-OhDo, Tae-DongKwon, Eung-ChanJang, Keun-MiLee, Suck-KangLee, Jong-YeonKim 저
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- 1,500원
health. Fatty acid oxidation rate is dependent on tissue types. However there has been no report on the relationship between the rate of fatty acid oxidation and carnitine transport system in outer mitochondrial membrane of many tissues. In this study, the rate of fatty acid oxidation and carnitine palmitoyltransferase(CPT) I activity in the carnitine transport system were measured to understand the metabolic characteristics of fatty acid in various tissues. Palmitic acid oxidation rate and CPT...

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