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961.

Effect of Fluoxetine on the Induction of Long-term Potentiation in Rat Frontal Cortex

Hwang-SooKim, Hyun-SokKim, SangJuneHahn, Myung-JunKim, ShinHeeYoon, Yang-HyeokJo, Myung-SukKim, Duck-JooRhie 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 1 295-300 (6 pages)

Hwang-SooKim, Hyun-SokKim, SangJuneHahn, Myung-JunKim, ShinHeeYoon, Yang-HyeokJo, Myung-SukKim, Duck-JooRhie 저
...
- 3,000원
Serotonin (5-hydroxytroptamine, 5-HT) has been shown to affect the induction of long-term potentiation (LTP) in the cortex such as the hippocampus, the visual cortex and the prefrontal cortex. Fluoxetine, as a selective serotonin reuptake inhibitor, is used in the management of a wide variety of psychological diseases. To study the effect of fluoxetine on the induction of LTP, we recorded the field potential in layer II/III of the frontal cortex from 3-wk-old. LTP was induced in horizontal input...
962.

Inhibitory Modulation of 5-Hydroxytryptamine on Corticostriatal Synaptic Transmission in Rat Brain Slice

SeJoonChoi, WonSoonChung, Ki-JungKim, Ki-WugSung, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 1 295-301 (7 pages)

SeJoonChoi, WonSoonChung, Ki-JungKim, Ki-WugSung, 저
...
- 3,000원
release from presynaptic nerve terminals, we measured the paired-pulse ratio (PPR) evoked by 2 identical pulses (50 ms interpulse interval), and found that PPR was increased (33.4⁑5.2%) by 5-HT, reflecting decreased neurotransmitter releasing probability. These results suggest that 5-HT may decrease neurotransmitter release probability of glutamatergic corticostriatal synapse and may be able to selectively decrease non-NMDA glutamate receptor-mediated synaptic transmission.
963.

Effects of Interleukin-1β and Tumor Necrosis Factor-α on the Release of Collagenase and Gelatinase from Osteoblasts

Jong-GabEun, Dong-HeonBaek, Se-WonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.5 6 269-274 (6 pages)

Jong-GabEun, Dong-HeonBaek, Se-WonKim 저
...
- 3,000원
A large number of factors such as osteotropic hormones, cytokines, or growth factors are related to the bone remodeling which is characterized by the coupling of osteoclast-mediated bone resorption and osteoblast-mediated bone formation. Recent investigations have indicated that cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) play a potential role in the bone resorption associated with a variety of pathological conditions such as inflammatory osteolytic disease....
964.

Expression of Natriuretic Peptide mRNAs in Isoproterenol-Induced Cardiac Hypertrophy in Rats

Soo-kyungKim, Gee-younKwon, Eun-sookChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 8 235-241 (7 pages)

Soo-kyungKim, Gee-younKwon, Eun-sookChang 저
...
- 3,000원
We examined the expression of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) mRNAs upon isoproterenol (Iso)-induced cardiac hypertrophy in rats. Then, we tried to investigate the effects of sympatholytics to see if they can modulate the expression of ANP and BNP. In this study, RT-PCR technique was used to characterize the expression of ANP and BNP in right atrium (RA) and left ventricle (LV) of the hypertrophied rat heart. Histologic findings indicated that stimulation of...
965.

Transition Metal Induces Apoptosis in MC3T3E1 Osteoblast Evidence of Free Radical Release

Han-JungChae, , Soo-WanChae, Jang-SookKang, Dong-HyeonYun, Byung-GwanBang, Mi-RaKang, Hyung-MinKim, Hyung-RyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.1 7 47-54 (8 pages)

Han-JungChae, , Soo-WanChae, Jang-SookKang, Dong-HyeonYun, Byung-GwanBang, Mi-RaKang, Hyung-MinKim, Hyung-RyongKim 저
...
- 3,000원
Transition metal ions including Se2⁢, Cd2⁢, Hg2⁢ or Mn2⁢ have been thought to disturb the bone metabolism directly. However, the mechanism for the bone lesion is unknown. In this study, we demonstrated that MC3T3E1 osteoblasts, exposed to various transition metal ions; selenium, cadmium, mercury or manganese, generated massive amounts of reactive oxygen species (ROS). The released ROS were completely quenched by free radical scavengers-N-acetyl cysteine (NAC), reduced...
966.

Decreased Voltage Dependent K+ Currents in Cerebral Arterial Smooth Muscle Cells of One-Kidney, One-Clip Goldblatt Hypertensive Rat

YoungSunOh, SeHoonKim, HoeSukKim, ByeongHwaJeon, SeokJongChang, KwangJinKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 3 471-479 (9 pages)

YoungSunOh, SeHoonKim, HoeSukKim, ByeongHwaJeon, SeokJongChang, KwangJinKim 저
...
- 3,000원
The Kv channel activity in vascular smooth muscle cell plays an important role in the regulation of membrane potential and blood vessel tone. It was postulated that increased blood vessel tone in hypertension was associated with alteration of Kv channel and membrane potential. Therefore, using whole cell mode of patch-clamp technique, the membrane potential and the 4-AP-sensitive Kv current in cerebral arterial smooth muscle cells were compared between normotensive rat and one-kidney, one-clip...
967.

Enhanced Expression of Inducible Nitric Oxide Synthase May Be Responsible for Altered Vascular Reactivity in Streptozotocin-induced Diabetic Rats

JaeKwonJang, YoungJinKang, HanGeukSeo, SookJaeSeo, KiChurlChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 2 375-382 (8 pages)

JaeKwonJang, YoungJinKang, HanGeukSeo, SookJaeSeo, KiChurlChang 저
...
- 3,000원
Growing evidence indicates that enhanced generation or actions of nitric oxide (NO) are implicated in the pathogenesis of hypertension in spontaneously hypertensive rats and diabetic nephropathy in streptozotocin (STZ)-induced diabetic rats. We investigated whether inducible nitric oxide synthase (iNOS) expression in STZ-induced diabetic rats is responsible for the alterations of vascular reactivity. Diabetic state was confirmed 28 days after injection of STZ (i.p) in rats by measuring blood...
968.

Systemic Injection of Lidocaine Induce Expression of c-fos mRNA and Protein in Adult Rat Brain

Han-JungChae, Jang-SookKang, Seoung-BumCho, Byung-GwanJin, Suk-JunWon, Byung-JooGwag, Hyung-RyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 9 69-74 (6 pages)

Han-JungChae, Jang-SookKang, Seoung-BumCho, Byung-GwanJin, Suk-JunWon, Byung-JooGwag, Hyung-RyongKim 저
...
- 3,000원
Both direct and indirect environmental stress to brain were increase the expression of transcription factor c-fos in various populations of neurons. In this study, we examined whether the intraperitoneal injections of lidocaine at doses inducing convulsion within 10 min increased the level of c-fos mRNA and protein in forebrain areas. In situ hybridization using [35S]UTP-labeled antisense c-fos, cRNA increased c-fos mRNA levels though hippocampal formation, piriform cortex, septum,...
969.

Rapid Induction of mRNA for Prostaglandin H Synthase in Ovine Meningeal Fibroblasts

MyeongJinNam, ClaraThore, DavidBusija 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 5 435-441 (7 pages)

MyeongJinNam, ClaraThore, DavidBusija 저
...
- 3,000원
We examined effects of interleukin 1α (IL1α) and phorbol 12, 13 dibutyrate (PDB), an activator of protein kinase C, on mRNA for Prostaglandin H synthase (PGHS) and prostanoid production in cultured ovine meningeal fibroblasts. Immuno- and morphologically-identified fibroblasts were derived from cerebral cortex and white matter from fetal lambs (approximately 120 days gestation) and grown to confluence on glass coverslips in 12 well plates. Levels of prostaglandin F2α and the stable...
970.

Inhibitory Effects of Ginseng Saponins on c-fos mRNA Expression and the Proliferation of Rat Aortic Vascular Smooth Muscle Cells Stimulated by Angiotensin II

WoongChoi, JinYoungJung, HunSikKim, YeoPyoYun, JongDaePark, HeeYulAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 8 201-207 (7 pages)

WoongChoi, JinYoungJung, HunSikKim, YeoPyoYun, JongDaePark, HeeYulAhn 저
...
- 3,000원
To evaluate the possibility that the ginseng saponins could be developed as an anti-arteriosclerotic agent, we examined the inhibitory effects of ginseng saponins (total saponin[TS], panaxatriol[PT], panaxadiol[PD]) on the expression of c-fos mRNA and the proliferation of cultured rat aortic vascular smooth muscle cells (VSMCs) stimulated by angiotensin II (Ang II). TS and PT (1.0 mg/ml) suppressed c-fos mRNA induction in VSMCs stimulated by 10-5 M Ang II. The order of inhibitory potency was...

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