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Sciatic nerve leachate of cattle causes neuronal differentiation of PC12 cells via ERK1/2 signaling pathway
Ziqiang Zhang, Yumei Liu, Xuemin Zhu, Lan Wei, Jiamin Zhu, Ke Shi, Guotao Wang, Li Pan 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 6 512-518 (7 pages)
in neural differentiation depends on the neurotrophins that Schwann cells secrete, and these factors are highly conserved among different species. To reduce the use of experimental animals, in this study, we made a leachate by using the sciatic nerve of cattle and explored its effect on neuronal differentiation of rat PC12 cells (a useful model for studying neuronal differentiation). Results showed the neurite outgrowth of PC12 cells treated with the cattle sciatic nerve leachate for 3, 6, and 9... -
In vitro neuronal and osteogenic differentiation of mesenchymal stem cells from human umbilical cord blood
Ki-Soo Park, Yong-Soon Lee , Kyung-Sun Kang 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 7 343-348 (6 pages)
Mesenchymal stem cells (MSCs) have the capabilities for self-renewal and differentiation into cells with the phenotypes of bone, cartilage, neurons and fat cells. These features of MSCs have attracted the attention of investigators for using MSCs for cell-based therapies to treat several human diseases. Because bone marrowderived cells, which are a main source of MSCs, are not always acceptable due to a significant drop in their cell number and proliferative/differentiation capacity with age,... -
Involvement of Endoplasmic Reticulum Stress Response in the Neuronal Differentiation
YoonMiCho, YoonSeongJang, Young-MinJang, Jin-YoungSeo, HoShikKim, JeongHwaLee, SeongWhanJeong, InKyungKim, Oh-JooKwon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.6 2 239-248 (10 pages)
of endoplasmic reticulum stress response (ERSR) genes were examined during the neuronal differentiation of rat fetal cortical precursor cells (rCPC) and rat pheochromocytoma PC12 cells. When rCPC were differentiated into neuronal cells for 7 days, early stem cell marker, nestin, expression was decreased from day 4, and neuronal markers such as neurofilament-L, -M and Tuj1 were increased after day 4. In this condition, expressions of BIP, ATF6, and phosphorylated PERK as well as their down stream... -
Differential Expressions of Gap Junction Proteins during Differentiation of Rat Neuronal Stem Cells
Yang. Se-Ran, Cho. Sung-Dae, Ahn. Nam-Shik, Jung. Ji-Won, Park. Joon-Suk, Tiep. Nguyen Ba, Park. Ki-Su, Hong. In-Sun, Jo. Eun-Hye, Seo. M 한국환경성돌연변이발암원학회 Environmental mutagens and carcinogens 5 Pages
한국환경성돌연변이발암원학회 Environmental mutagens and carcinogens 2003, Vol.23 No.1 11-15 (5 pages)
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Proteomic Analysis of Time-Dependant Difference of Protein Expression Profile Changes during Neuronal Differentiation of Mouse Embryonic Stem Cells
Shim. Jung-Hee, Cho. Sun-A, Seo. Min-Ji, Kim. Jung-Hee, Ryu. Na-Kyung, Yoo. Kyung-Hyun, Yang. Moon-Hee, Kim. Se-Yoon, Bahk. Young-Yil, Pa 한국분자세포생물학회 Molecules and cells 6 Pages
한국분자세포생물학회 Molecules and cells 2010, Vol.29 No.3 239-244 (6 pages)
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Ginsenosides Rb1 and Rg1 Decrease Proliferation but Increase Neuronal Differentiation of Hippocampal Neural Progenitor Cells
윤영주, 이준석, 김영숙, 양병환, 손현, Yoon. Young-Ju, Lee. Jun-Seok, Kim. Young-Sook, Yang. Byung-Hwan, Son. Hyeon 한국발생생물학회 발생과 생식 7 Pages
한국발생생물학회 발생과 생식 2006, Vol.10 No.3 169-175 (7 pages)
전세계적으로 널리 복용되고 있음에도 불구하고 인삼이 중추신경계에 미치는 효과에 대한 세포수준에서의 증거는 별로 없다. 따라서 본 연구자들은 지금까지 보고된 30여종 이상의 ginsenosides 중에서 인삼 효과의 주된 활성성분으로 알려져 있는 Rb1과 Rg1을 이용해 해마신경전구세포의 분화와 증식에 미치는 효과를 연구하였다. 증식실험결과 Rb1과 Rg1을 3일 동안 해마신경전구세포에 처리하면 대조군에 비해 BrdU(+)세포수가 상당히 감소한 반면에 분화조건에서 Rb1과 Rg1을 처리했을 때는 신경세포특이적인 MAP2 단백질을 발현하는... -
Neuronal Differentiation of PC12 Cells Cultured on Growth Factor-Loaded Nanoparticles Coated on PLGA Microspheres
Park. Keun-Hong, Kim. Hye-Min, Na. Kun 한국미생물생명공학회 Journal of microbiology and biotechnology 6 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2009, Vol.19 No.11 1490-1495 (6 pages)


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