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Inhibitory Activity of Sedum middendorffianum-Derived 4-Hydroxybenzoic Acid and Vanillic Acid on the Type III Secretion System of Pseudomonas syringae pv. tomato DC3000
Ji Eun Kang, Byeong Jun Jeon, Min Young Park, Beom Seok Kim 한국식물병리학회 The Plant Pathology Journal 10 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 6호 8 608-617 (10 pages)
The type III secretion system (T3SS) is a key virulence determinant in the infection process of Pseudomonas syringae pv. tomato DC3000 (Pst DC3000). Pathogen constructs a type III apparatus to translocate effector proteins into host cells, which have various roles in pathogenesis. 4-Hydroxybenozic acid and vanillic acid were identified from root extract of Sedum middendorffianum to have inhibitory effect on promoter activity of hrpA gene encoding the structural protein of the T3SS apparatus. The... -
Characterization of Type VI Secretion System in Xanthomonas oryzae pv. oryzae and Its Role in Virulence to Rice
Yeounju Choi, Namgyu Kim, Mohamed Mannaa, Hongsup Kim, Jungwook Park, Hyejung Jung, Gil Han, Hyun-Hee Lee, Young-Su Seo 한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 3호 9 289-296 (8 pages)
Type VI secretion system (T6SS) is a contact-dependent secretion system, employed by most gram-negative bacteria for translocating effector proteins to target cells. The present study was conducted to investigate T6SS in Xanthomonas oryzae pv. oryzae (Xoo), which causes bacterial blight in rice, and to unveil its functions. Two T6SS clusters were found in the genome of Xoo PXO99A. The deletion mutants, Δhcp1, Δhcp2, and Δhcp12, targeting the hcp gene in each cluster, and a double-deletion... -
Symposium : Molecular Plant-Microbe Interactions ; Molecular Basis of the Hrp Pathogenicity of the Fire Blight Pathogen Erwinia amylovora: a Type 3 Protein Secretion System Encoded in a Pathogenicity Island
한국식물병리학회 The Plant Pathology Journal 6 Pages
한국식물병리학회 The Plant Pathology Journal 2001, 17권 2호 3 77-82 (6 pages)
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Salmonella Type III Secretion System을 이용한 단백질 분비시스템 개발
홍순호, Hong. Soon-Ho 한국생물공학회 KSBB Journal 4 Pages
한국생물공학회 KSBB Journal 2009, Vol.24 No.4 393-396 (4 pages)
단백질을 동물세포내부로 직접 주입할 수 있는 살모넬라 균주의 T3SS를 활용하여 모델 단백질인 lipase를 세포외부로 분비하는 시스템을 제작하였다. T3SS의 effector 단백질인 SlrP, SptP의 N-말단부분과 lipase를 fusion하였다. Lipase 분비실험의 결과 S. typhimurium SL1344 (sptP-tliA) 균주의 경우 lipase 활성도가 약 2.6배 증가하는 결과를 얻을 수 있었다. 본 실험결과를 바탕으로 T3SS에 관한 연구가 더욱 활발히 이루어진다면, T3SS를 신개념 약물전달시스템으로 활용이 가능해 지리라 예상된다. -
Effect of Acidic pH on the Invasion Efficiency and the Type III Secretion System of Burkholderia thailandensis
Jitprasutwit. Siroj, Thaewpia. Wisansanee, Muangsombut. Veerachat, Lulitanond. Aroonlug, Leelayuwat. Chanvit, Lertmemongkolchai. Ganj 한국미생물학회 The journal of microbiology 7 Pages
한국미생물학회 The journal of microbiology 2010, Vol.48 No.4 526-532 (7 pages)
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Cell Death Mediated by Vibrio parahaemolyticus Type III Secretion System 1 Is Dependent on ERK1/2 MAPK, but Independent of Caspases
Yang. Yu-Jin, Lee. Na-Kyung, Lee. Na-Yeon, Lee. Jong-Woong, Park. Soon-Jung 한국미생물생명공학회 Journal of microbiology and biotechnology 11 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2011, Vol.21 No.9 903-913 (11 pages)
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ANP Inhibits Surfactant Secretion from Isoproterenol Stimulated Alveolar Type II Cells
YoungManLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 8 65-70 (6 pages)
surfactant secretion from alveolar type II cell(AT II cell) during circulatory derangement in adult respiratory distress syndrome (ARDS), the secretion of surfactant from AT II cells was evaluated in purely isolated AT II cultures from rat lungs. For the simulation of sympathetic stimulation during circulatory derangement, primary AT II cultures were incubated with isoproterenol and IBMX. In this isoproterenol stimulated AT II cells, ANP were added in the media for the investigation of effect of... -
Genome-Wide Analysis of Type VI System Clusters and Effectors in Burkholderia Species
한국식물병리학회 The Plant Pathology Journal 12 Pages
한국식물병리학회 The Plant Pathology Journal 2018, 34권 1호 2 11-22 (12 pages)
Type VI secretion system (T6SS) has been discovered in a variety of gram-negative bacteria as a versatile weapon to stimulate the killing of eukaryotic cells or prokaryotic competitors. Type VI secretion effectors (T6SEs) are well known as key virulence factors for important pathogenic bacteria. In many Burkholderia species, T6SS has evolved as the most complicated secretion pathway with distinguished types to translocate diverse T6SEs, suggesting their essential roles in this genus. Here we... -
Development of a Protein Secretion System with the Application of Sec-dependent Protein Secretion Components
Kim. Sam-Woong, Kim. Young-Hee, Yoo. Ah-Young, Yu. Jong-Earn, Hur. Jin, Lee. John-Hwa, Cha. Jae-Ho, Kang. Ho-Young 한국미생물생명공학회 Journal of microbiology and biotechnology 8 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2007, Vol.17 No.8 1316-1323 (8 pages)


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