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Mathematical Modeling and Simulation of spread of FMD and HPAI in the Republic of Korea
Hachung Yoon, Chang Hyung Lee, Pil Won Kim, Hyo Jeong Lee, Woo-seog Jeong, Jida Choi, Yong Myung Kang, Jee Hye Kim, Chung Sik Jung, Hong 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 47 107-108 (2 pages)
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A quantitative modeling approach to estimate the risks posed by the smuggled animal products contaminated with Foot-and-Mouth Disease (FMD) virus
KiOkHong, GilHongLee, SonIlPak 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 9 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2005, 제 45권 제 2호 12 223-231 (9 pages)
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Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin
Min-HoPark, Seok-HoShin, Jin-JuByeon, Gwan-HoLee, Byung-YongYu, YoungG.Shin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.1 13 107-115 (9 pages)
of PBPK modeling and simulation for this study. Compared to caffeine, the PBPK modeling for ciprofloxacin was challenging due to several factors including solubility, permeability, clearance and tissue distribution etc. Therefore, intensive parameter sensitivity analysis (PSA) was conducted to optimize the PBPK model for ciprofloxacin. Overall, the increase in Cmax of caffeine by ciprofloxacin was not significant. However, the increase in AUC was observed and was proportional to the administered... -
Spatial reproducibility of complex fractionated atrial electrogram depending on the direction and configuration of bipolar electrodes: an in-silico modeling study
Jun-SeopSong, Young-SeonLee, MinkiHwang, Jung-KeeLee, ChangyongLi, BoyoungJoung, Moon-HyoungLee, EunBoShim, Hui-NamPak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.5 8 507-514 (8 pages)
Although 3D-complex fractionated atrial electrogram (CFAE) mapping is useful in radiofrequency catheter ablation for persistent atrial fibrillation (AF), the directions and configuration of the bipolar electrodes may affect the electrogram. This study aimed to compare the spatial reproducibility of CFAE by changing the catheter orientations and electrode distance in an in -silico left atrium (LA). We conducted this study by importing the heart CT image of a patient with AF into a 3D-homogeneous... -
Modeling of the Parathyroid Hormone Response after Calcium Intake in Healthy Subjects
JaeEunAhn, SangilJeon, JongtaeLee, SeunghoonHan, Dong-SeokYim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.3 4 217-223 (7 pages)
Plasma ionized calcium (Ca2+) concentrations are tightly regulated in the body and maintained within a narrow range; thus it is challenging to quantify calcium absorption under normal physiologic conditions. This study aimed to develop a mechanistic model for the parathyroid hormone (PTH) response after calcium intake and indirectly compare the difference in oral calcium absorption from PTH responses. PTH and Ca2+ concentrations were collected from 24 subjects from a clinical trial performed to... -
Modeling of Arrhythmogenic Automaticity Induced by Stretch in Rat Atrial Myocytes
JaeBoumYoum, ChaeHunLeem, YinHuaZhang, NariKim, JinHan, YungE.Earm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.5 8 267-274 (8 pages)
Since first discovered in chick skeletal muscles, stretch-activated channels (SACs) have been proposed as a probable mechano-transducer of the mechanical stimulus at the cellular level. Channel properties have been studied in both the single-channel and the whole-cell level. There is growing evidence to indicate that major stretch-induced changes in electrical activity are mediated by activation of these channels. We aimed to investigate the mechanism of stretch-induced automaticity by... -
The Influence of Maternal Factors and Child Self-regulation on Peer Initiative: A Structural Equation Modeling Approach
Seonhyung Choi, Sunhee Kim 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 24 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2021, Vol.15 No.3 1 1-24 (24 pages)
or unfriendly. This study used structural equation modeling to examine the contributions of mother’s coaching competence, parenting behavior, and child self-regulation to peer initiative. Participants comprised mothers of children aged 3 to 5 years (n = 343) in Korea and their teachers (n = 39). Structural equation modeling indicated that the relationship between mothers’ coaching competence and friendly peer initiative was fully mediated by maternal affection and child self-regulation.... -
The Impact of Sample Size on Three-Level Quadratic Cross-Classified Multiple Membership Growth Curve Modeling Estimation
정혜원(Chung Hyewon), 전현정(Jeon Hyeonjeong), 박소영(Park Soyoung) 한국교육학회 교육학연구 22 Pages
한국교육학회 교육학연구 2022, 60권 7호 1 1-22 (22 pages)
a minimum sample size requirement for the three-level quadratic cross-classified multiple membership growth curve modeling, this study employed a simulation under a variety of conditions including the number of measurement occasions (4, 5, and 6), the number of groups (30, 50, 100, and 200), average group size (10, 30, and 50), and multiple membership rates (20% and 40%). Across all of the simulated conditions, no substantial bias was found for the fixed effect and level-one variance component... -
A Comparison of Three Bayesian Point Estimates for Cross-Classified Multiple Membership Growth Curve Modeling
Chung Hyewon, Jeon Hyeonjeong, Park Soyoung 한국교육학회 교육학연구 26 Pages
한국교육학회 교육학연구 2021, 59권 7호 7 167-192 (26 pages)
mode estimates of the between-school variances in the intercept and slope were substantially overestimated. In general, with the inverse Wishart prior, the Markov chain Monte Carlo (MCMC) posterior median is recommended for cross-classified multiple membership growth curve modeling, except under certain conditions. With the uniform prior, the MCMC mode is recommended for estimating cross-classified multiple membership growth curve modeling rather than the MCMC posterior mean or posterior median. -
Development and Validation of the Theory of Transition to College Student : A Sequential Mixed Method of Grounded Theory and Structural Equation Modeling
Hong Song-Ee 한국교육학회 교육학연구 36 Pages
한국교육학회 교육학연구 2021, 59권 3호 3 55-90 (36 pages)
a questionnaire was developed based on the established transition theory. The validation of the theory was analyzed through structural equation modeling (SEM), and a multi-group analysis was conducted to find out what differences existed in the structural model for dormitory, self-catering, and commuting to school. As a result of the qualitative study, 112 concepts, 34 subcategories, and 9 categories were derived from open coding. As a result of the quantitative analysis through SEM, first, the...


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