- 사람의 배양세포염색체의, 방사선감수성에 관한 연구
- Studies on the Radiosensitivity of the Chromosomes in Cultured Human Cells
- ㆍ 저자명
- 강영선,김영진,이정길
- ㆍ 간행물명
- 동물학회지
- ㆍ 권/호정보
- 1967년|10권 1호|pp.17-20 (4 pages)
- ㆍ 발행정보
- 한국동물학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
The present experiment was perform to investigate the frequencies of chromosome aberration with special regard to the chromosome groups and the various time intervals after X-irradiation (60 r) in ormal human foetus cells grown in culture. The cytological preparations were prepared at every 5 through 30 hours after X-irradiation by the air-drying method. 1. The frequencies of chormosome aberration are on the whole decreased as tie elapses after irradiation and this is thought to be due to gradual recovery with time . However, a slight increase in frequencies is observed at 25 and 30 hours after irradiation respectively. This shows that the cells at the these periods are more sensitivity to X-irradation , and those cells are thought to be at G$_2$ and late S stage at the time of irradiation respectively, so t is evident that G$_2$ and late S stages a the time of irradiation respectively , so it is evident that G$_2$ and late S stages are more sensitive to X-irradiation than any other stages. 2. The frequencies of chormosome aberration are decreased in descending order of chormosome group number. The differences among these frequencies are highly significant statistically . Therefore it can be concluded that there is a highly significant difference in radiosensitivity among chromosome groups. that is, the chromosomes of the group A are the most radiosensitive , followed by B, C, D ,E and G in descending order.