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갑상선기능항진증(甲狀腺機能亢進症)에 있어서 $T_3RU$ 및 $T_4$에 관(關)한 임상적(臨床的) 연구(硏究)
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  • 갑상선기능항진증(甲狀腺機能亢進症)에 있어서 $T_3RU$ 및 $T_4$에 관(關)한 임상적(臨床的) 연구(硏究)
  • A Clinical Study on $^{125}I;T_3$ Resin Uptake Rate and Serum Thyroxin ($T_4$) in Hyperthyroidism
저자명
문언수,박요한,조창호,박인수,이종석,이학중,Moon. Ern-Soo,Park. Yoh-Han,Cho. Chang-Ho,Park. In-Soo,Lee. Chong-Suk,Lee. Hak-Choong
간행물명
大韓核醫學會誌
권/호정보
1978년|12권 2호|pp.23-31 (9 pages)
발행정보
대한핵의학회
파일정보
정기간행물|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Hyperthyroidism may be defined as those clinical conditions which result from an increase in the circulating levels of one or both thyroid hormones. Hyperthyroidism in broad sense could be classified with toxic diffuse goiter, toxic adenomatous goiter, and toxic multinodular goiter on the basis of the circulating thyroid hormone levels. For this study, the subject included 94 cases with hyperthyroidism were presented in 77 with toxic diffuse goiter, 8 with toxic adenomatous goiter, and 9 with toxic multinodular goiter on the levels of $^{125}IT_3$ resin uptake rate and serum thyroxine ($T_4$). The observed results were as follows: 1) In the cases of hyperthyroidism including toxic diffuse goiter, toxic adenomatous goiter, and toxic multinodular goiter, 20.21% of the patients were male and 79.79% female. The majority of the patients were in 2nd to 4th decades of their lives. 2) There were objective signs clearly manifested in hyperthyroidism including toxic diffuse goiter and toxic adenomatous goiter which were rare in the multinodular goiter. The clinical signs in toxic diffuse and toxic adenomatous goiter included wide pulse pressure, tachycardia, systolic murmur, exophthalmos, tremor and warm skin etc. (Table 3.) 3) The most freauent complaints of the patients with hyperthyroidism were palpitation, weight loss, increased appetite, perspiration, heat intolerance, nervousness, exertional dyspnea, and menstrual disturbance etc. (Table 4.) There was no clear difference in the incidence of symptoms between toxic diffuse goiter and toxic adenomatous goiter, but there was clear difference between toxic multinodular goiter. 4) Considering of results of $^{125}IT_3$ resin uptake rate and serum $T_4$ level in toxic diffuse goiter, toxic adenomatous goiter and toxic multinodular goiter, $^{125}I;T_3$ resin uptake rate was $49.15{pm}9.94%$ (mean) and serum $T_4;21.29{pm}7.04ug/dl$ (mean) in toxic diffuse goiter. In toxic multinodular goiter, $^{125}I;T_3$ resin uptake rate was $32.47{pm}6.74%$ (mean) and serum $T_4$ level $11.03{pm}5.0ug/dl$, and then there was clear difference in the results of $^{125}I;T_3$ resin uptake rate and serum $T_4$ between toxic diffuse goiter and toxic multinodular goiter. The levels of $^{125}I;T_3$ resin uptake rate and serum $T_4$ in toxic adenomatous goiter were $40.32{pm}13.08%$ (mean), $15.47{pm}8.25ug/dl$ (mean) respectively, so there was no clear difference between toxic diffuse goiter and toxic adenomatous goiter. 5) There was no significant differnece in length and width performed with thyroid scanning in toxic diffuse goiter, toxic adenomatous goiter, and toxic multinodular goiter.