Forty three percutaneous bone biopsy(PBB)procedures were performed under fluoroscopic guide at department of diagnostic radiology of Kosin Medical College Pusan Korea. the overall accuracy was 88.4% (38/43)true positive rate was 74%(32cases) true negatice was 14% (6cases) false negative was 12%(5 cases). In cases of suspected metastasis with or without known primary PBB occasionally provided the final tissue diagnosis and was helpful in tumor staging and seeking the primary site. In cases of primary bone tumor the tissue diagnosis obtained by PBB was hekpful for planning future therapy and confirmed the recurrent tumor and residual lesion following treatment. There wan no serious complication related to PBB. In conclusion PBB is simple safe economic and accurate diagnostic tool PBB gave the final tissue diagnosis. It not only provided accurate tumor staging and future therapeutic plan before treatment and also helped in the management of follow-up in patients with recurrent or residual lesion.