Turbulent flow characteristics and heat transfer in a three-dimensional room with a desk-type heat generating obstacle have been investigated numerically by the k-$varepsilon$ two equation turbulence model. The room mole has one supply opening on the ceiling and two exhaust openings on the side walls. Th results of the flow structure and heat transfer have been represented for air for the inlet velocities in the range 0.1-10.0m/s. As the results of the three dimensional simulations, the relationships between mean Nusselt number and Reynolds number are clarified.