- 이온교환수지를 이용한 피라세탐의 in vitro 방출조절
- ㆍ 저자명
- 황영숙,이경태,서성훈,Hwang. Young-Sook,Lee. Kyung-Tae,Seo. Seong-Hoon
- ㆍ 간행물명
- 藥劑學會誌
- ㆍ 권/호정보
- 1999년|29권 2호|pp.105-109 (5 pages)
- ㆍ 발행정보
- 한국약제학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
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The sustained release of piracetam by complexation with ion exchange resin was prepared. The complex was coated with Eudragit RS100 and their releases in vitro were conducted with various different kinds of medium solution. Dissolution rate increased as ionic strength, acidity and drug concentrations increased and reached its maximal plateau concentration within 5 min. Based on these data, The controlled release of piracetam using ion-exchange piracetam complex coated with Eudragit RS100 could be available.