- 새로운 10-옥소다우노마이시논 유도체의 합성
- Syntheses of Novel 10-Oxodaunomycinone Derivatives
- ㆍ 저자명
- 노영쇠,김선자,조인호,신홍식
- ㆍ 간행물명
- 약학회지
- ㆍ 권/호정보
- 1999년|43권 1호|pp.11-15 (5 pages)
- ㆍ 발행정보
- 대한약학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
A brief route for regiospecific synthesis of novel 10-Oxodaunomycinone Derivatives (10a, b) is described. Dimethoxy-l-tetralone 4 was converted to acetyl tetralone (5a, b) which was oxidized with oxygen to obtain cis-diol compound (8a, b). The construction of (10a, b) was completed by the condensation of phthaloyl dichloride 9 with cis-diol (8a, b)