- 세파클러의 결정형
- ㆍ 저자명
- 손영택,전임작,Sohn. Young-Taek,Jeon. Im-Jak
- ㆍ 간행물명
- 藥劑學會誌
- ㆍ 권/호정보
- 2000년|30권 3호|pp.201-205 (5 pages)
- ㆍ 발행정보
- 한국약제학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
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Three new polymorphic modifications were prepared by recrystallization under various conditions and characterized by DSC and X-ray crystallography. In pH 4.0 buffer at $37{pm}0.5^{circ}C$, the polymorphic modifications showed significant differences in the dissolution rate. The dissolution rate of Mod. 4, amorphous form, was faster than that of marketed cefaclor (Mod. 1). When all modifications were stored at 52% RH, 95% RH and in silica gel desiccator, any polymorphic transformation was not observed.