For developing a new Tire Manufacturing Cell, the cooperation between the designer of facilities and the designer of system is very important. The purpose of this paper is to develop a simulation model that can be applied to the system design of Tire Manufacturing Cell. The mechanic characteristics of new facilities are obtained from facility design team and the simulation model is developed with SIMPLE++ using those input data. A model for estimating the number of tire drum required is also suggested and it is verified with numerical examples. The results of simulations can be fed back to the facility design team and used for modifying the structure of the facilities.