In this brief, the design method of robust non-fragile decentralized controllers for uncertain large-scale interconnected systems is proposed. Based on Lyapunov second method, a sufficient condition for asymtotic stability is derived in terms of a linear matrix inequality (LMI), and the measure of non-fragility in controller is presented. The solutions of the LMI can be easily obtained using efficient convex optimization techniques. A numerical example is given to illustrate the proposed method.