We report a fuel cell power supply unit for mobile phone which operates at room temperature and ambient pressure using liquid methanol and air. The unit consists of a direct methanol fuel cell (DMFC) and a back-up battery connected parallely to the fuel cell. DMFC supplies half of the required power and the back-up battery supplies the other half during talk mode. In standby mode, DMFC covers $100\%$ of the required power and charges the back-up battery as well, Eight unit cells, each having $9 cm^2$ of active area, were connected in series in order to raise the output volotage to $2.5~3.9V$, which is typical for most mobile phones.