Pharmacokinetics and oral bioavailability of levosulpiride was determined in Korean healthy male volunteers. Thirty subjects received a single oral dose (25 mg) of a tablet in a randomized $2{ imes}2$ cross-over design. The plasma concentrations of levosulpiride were measured by HPLC and compared with those reported in the literature. Pharmacokinetic parameters for $Isomeric^{circledR}$ tablet (levosulpiride 25 mg) were revealed as follows: $AUC_{inf};737.1{pm}176.9;ng{cdot}hr/ml,;C_{max};56.4{pm}20.1;ng/ml,;T_{max};4.2{pm}1.6;hr,;K_a;1.00{pm}1.09;hr^{-1},;K_{el};0.08{pm}0.02;hr^{-1},;and;t_{1/2};8.8{pm}1.9;hr$. The rate constant of the absorption phase was obtained based on the first-order kinetics. In the aspect of bioavailability, $Isomeric^{circledR}$ tablet was bioequivalent to the other product $(Levopride^{circledR};tablet)$ available in the Korea market. Intersubject variations and race differences were show in comparison with the published data in the literature, even though there was a linear relationship between dose ad extent of bioavailability.