- 프탈레이트의 노출 정도 및 인구학적 특성과의 관련요인
- ㆍ 저자명
- 구정완,이강숙,박정일,구현정,이병무
- ㆍ 간행물명
- Journal of toxicology and public health : an official journal of the Korean Society of Toxicology
- ㆍ 권/호정보
- 2003년|19권 4호|pp.297-301 (5 pages)
- ㆍ 발행정보
- 한국독성학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
To investigate biomarker-based exposure to phthalates and related factors with demographics, 100 subjects who had participated in comprehensive health check-up were selected. We collected demographics through questionnaires and analyzed urine samples for 5 phthalates. Statistical likelihoods and regression methods were applied for data analysis using censored data. The highest levels of urine phthalates were 216$mu extrm{g}$/ml in di-isodecyl phthalate, 29.0$mu extrm{g}$/ml in di-butyl phthalate, 5.78$mu extrm{g}$/ml in di-(2-ethylhexyl) phthalate. The median values of di-(2-ethylhexyl) phthalate were 0.2340 $mu extrm{g}$/ml for male smokers, 0.0399 $mu extrm{g}$/ml for male non-smokers and 0.0085 $mu extrm{g}$/ml for female non-smokers, respectively. Di-(2-ethylhexyl) phthalate, benzyl butyl phthalate and di-isodecyl phthalate were higher in males than in females. In addition, mono-2-ethylhexyl phthalate was decreased with age. Our findings suggest that there might be significant demographic variations in exposure and/or metabolism of phthalates, and that health-risk assessment for phthalate exposure in humans should consider different potential risk groups.