The purpose of this paper is to analyze quantitative and qualitative effects through input-output analysis and AHP(Analytic Hierarchy Process) method for checking the effects inducing high value to Jeju region economy by culture industry. In analysis results, Investment to culture industry has a positive effect on Income effect, employment effect, linking the other industry on Jeju region economy. And so, for activation of the Jeju region economy, Culture Industry based on Knowledge should be cultivated.