Vibration response of the tower structure of a 750kW wind turbine (W/T) generator is investigated by measurement and analysis. Acceleration response of the W/T tower under various operation condition is monitored in real time by the vibration monitoring system using LabVIEW. Resonance state of the tower structure is diagnosed in the operating speed range. Resonance frequency range of the test model is investigated with the wind speed data of the test site. To predict the tower resonance frequency, tower is modeled as an equivalent beam with a lumped mass and Rayleigh energy method is applied. Calculated tower bending frequency is in good agreement with the measured value and the result shows that the simplified model can be used in the design stage of the W/T tower.