We investigated the change of the blink rate by wearing soft contact lens(SCL). Eight types of soft contact lenses were worn by twelve asymptomatic contact lens wearers. When wearers were worn SCLs for 15 min, the average blink rate was 20.0 blinks/min, which was a statistically significant increase compared to 13.3 blinks/min, the average blink rate of non-SCL-worn eye. After 8 hr of lens wear, the average blink rate was 24.3 blinks/min, and it was 11 blinks/min more than that of non-SCL-worn eye and 4 blinks/min more than that of 15 min SCL-worn eye. There were a little difference of the blink rate in types of lens, which the blink rate range of all lens after 15 min of lens wear was 18.1~20.9 blinks/min and that after 8 hr of lens wear was 22.9~24.9 blinks/min. When wearing A lens(vifilcon, 0.06 mm) having thin center thickness, wearers showing difference of 10.0~11.9 blinks/min between non-SCL-worn eye and 15 min SCL-worn eye reached 16.7% and it was more than that of relatively thick B lens(0.17 mm) and C lens(0.14 mm). This result suggest that the center thickness was not unique factor of the blink rate change and other factors would have synthetically influence on the blink rate change. In the case of B lens and C lens of hilafilcon material but having different center thickness and water content, wearers increasing more than 4.0 blinks/min after 8 hr of lens wear was 58.3% and 41.7%, respectively. This result have provided information that the lenses of similar materials but different center thickness and water content could cause individually the different change of the blink rate.