Pneumatic vibration isolator has a wide application for ground-vibration isolation of vibration-sensitive equipments. Recent advances In precision machine tools and instruments such as nano-technology or medical devices require a better isolation performance, which can be efficiently done by precise modeling- and design- of the isolation system. This paper will discuss an efficient transmissibility design method for pneumatic vibration isolator by employing the complex stiffness model of dual-chamber pneumatic spring developed in our previous research. Three design parameters of volume ratio between the two pneumatic chambers, the geometry of capillary tube connecting the two pneumatic chambers and finally the stiffness of diaphragm necessarily employed for prevention of air leakage were found to be important factors in transmissibility design. Based on design technique that maximizes damping of dual-chamber pneumatic spring, trade-off among the resonance frequency of transmissibility, peak transmissibility and transmissibility in high frequency range was found, which was not ever stated in previous researches. Furthermore this paper will discuss about negative role of diaphragm in transmissibility design. Then the design method proposed in this paper will be illustrated through experiment at measurements.