Purpose: This study was conducted to examine the factors related to quality of life in elderly. Methods: This was a descriptive correlation study. The subjects were 356 elderly over 65 years old. Data were analyzed by descriptive statistics, Pearson correlation coefficients, and multiple regression with a SAS statistics. Results: The predictors of quality of life in elderly were depression, life satisfaction, self esteem, economic state, family support, perceived health state, and age. These factors explained 71.9% of the total variance. Conclusion: These findings suggest the need to develop nursing strategy to improve quality of life in elderly. To improve the quality of life in elderly, the above major influencing factors should be considered.